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Protein

60 kDa chaperonin

Gene

groL

Organism
Elusimicrobium minutum (strain Pei191)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Ordered Locus Names:Emin_0924
OrganismiElusimicrobium minutum (strain Pei191)
Taxonomic identifieri445932 [NCBI]
Taxonomic lineageiBacteriaElusimicrobiaElusimicrobiaElusimicrobialesElusimicrobiaceaeElusimicrobium
Proteomesi
  • UP000001029 Componenti: Chromosome

Subcellular locationi

B2KD81:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001300141 – 54260 kDa chaperoninAdd BLAST542

Proteomic databases

PRIDEiB2KD81.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi445932.Emin_0924.

Structurei

3D structure databases

SMRiB2KD81.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiTDTDKME.
OrthoDBiPOG091H00E7.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.

Sequencei

Sequence statusi: Complete.

B2KD81-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKQIVYGDE ARAKMKAGIE KVAKAVSVTL GPKGRSVVLE KKFGSPLIID
60 70 80 90 100
DGVTIAKDIE LEDKFENMGA QLIREVASKT NDIAGDGTTT ATVLTHAILT
110 120 130 140 150
EGIKNITAGA NPTLVKKGIE MAVETVKEEL KKMQRPVETK EEKAQIATIS
160 170 180 190 200
ANDRMVGELI AEAMEKVGHE GVITVEEGKT ATTELQVVEG MQFDRGYISP
210 220 230 240 250
YFVTDSERME CVLEDCQIIL ADKKVSSMNE LLPLLEGIVK NGRNFLIIAE
260 270 280 290 300
DVDGEALATL VVNRLRGTLK GCAVKAPGFG DRRKEMLEDI AILTGGQVIA
310 320 330 340 350
EERGMKLETA TLDMLGSAKR VVIDKENATI VSGEGDKKKI EARAEQIRKQ
360 370 380 390 400
IENSTSDYDK EKLQERLAKL SGGVAVISVG AATETEMKAK KAKVEDAKNA
410 420 430 440 450
TKAGVEEGLI PGGGVALTRC EGAVGKLKAD NEDVQTGINI VKKALTAPLY
460 470 480 490 500
QIAFNAGLDG SVVVENVRNA KGNQGFDADT GEYVDMIKAG VVDAVKVVRI
510 520 530 540
GLENAASIAA TVLLTEALVA DIPEEKGAAP MGHPGMGGMG MM
Length:542
Mass (Da):57,622
Last modified:June 10, 2008 - v1
Checksum:i35BA619E28FE9870
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001055 Genomic DNA. Translation: ACC98477.1.
RefSeqiWP_012415092.1. NC_010644.1.

Genome annotation databases

EnsemblBacteriaiACC98477; ACC98477; Emin_0924.
KEGGiemi:Emin_0924.

Similar proteinsi

Entry informationi

Entry nameiCH60_ELUMP
AccessioniPrimary (citable) accession number: B2KD81
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 10, 2008
Last modified: October 25, 2017
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families