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B2KD56 (SYR_ELUMP) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Emin_0897
OrganismElusimicrobium minutum (strain Pei191) [Complete proteome] [HAMAP]
Taxonomic identifier445932 [NCBI]
Taxonomic lineageBacteriaElusimicrobiaElusimicrobiaElusimicrobialesElusimicrobiaceaeElusimicrobium

Protein attributes

Sequence length532 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 532532Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000198900

Regions

Motif122 – 13211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
B2KD56 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: E053EF06446F8DDC

FASTA53259,933
        10         20         30         40         50         60 
MLDNLKKDIE TKLFNAEVFE GAVLPPVDLT PAPPHTGADI SLTWAMSAAK TLKKNPLEIA 

        70         80         90        100        110        120 
KAAVKVISEV TFVASASYAA PGFINIILED SFISSSALDR RLKNRKTAGE NKERVLIEFV 

       130        140        150        160        170        180 
SANPTGPLHV ASGRGASLGD SLVRIFNALG IQCDSEYYVN DSGNQAMLLG VSLKARVNGQ 

       190        200        210        220        230        240 
EPPENGYHGS YLIEMADEIR EMSKDWTEEQ FSIYAIEYLI KTHQRDMQAF NVNFTRWFRE 

       250        260        270        280        290        300 
SELYKESLPA KALDFLKEKG LAYEADGAVW FGTTKDNDDK DRVLVRADGR PTYFLADIAY 

       310        320        330        340        350        360 
HKNKYDRGFT TLVDILGADH HGYVPRMKAA VKALGENEES FVPIIHQLVH LIEGGEKVKM 

       370        380        390        400        410        420 
SKRSGRFITL KELTEEVGAD ACRFLFASRT PDAHMNFDID LAKKRTNENP VFYVQYVHAR 

       430        440        450        460        470        480 
AASIARMAEQ KHLQQAENLV DFKLTPQERT LLIKILWFKH ALKNCVRDMS PHHLTTYLIE 

       490        500        510        520        530 
LAGNFHSFYD ACRVVDEDNP QTTAHRLLIC DRVRERIKKG LEFLGVSAPE EM 

« Hide

References

[1]"Genomic analysis of 'Elusimicrobium minutum,' the first cultivated representative of the phylum 'Elusimicrobia' (formerly termite group 1)."
Herlemann D.P.R., Geissinger O., Ikeda-Ohtsubo W., Kunin V., Sun H., Lapidus A., Hugenholtz P., Brune A.
Appl. Environ. Microbiol. 75:2841-2849(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Pei191.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001055 Genomic DNA. Translation: ACC98452.1.
RefSeqYP_001875789.1. NC_010644.1.

3D structure databases

ProteinModelPortalB2KD56.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING445932.Emin_0897.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACC98452; ACC98452; Emin_0897.
GeneID6263872.
KEGGemi:Emin_0897.
PATRIC21849020. VBIEluMin86178_0938.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMARFIMLTR.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycEMIN445932:GHM0-931-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSYR_ELUMP
AccessionPrimary (citable) accession number: B2KD56
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 10, 2008
Last modified: April 16, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries