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Protein

Chitooligosaccharide deacetylase

Gene

chbG

Organism
Yersinia pseudotuberculosis serotype IB (strain PB1/+)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.UniRule annotation

Catalytic activityi

N,N'-diacetylchitobiose + H2O = N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine + acetate.UniRule annotation
Diacetylchitobiose-6-phosphate + H2O = N-monoacetylchitobiose-6-phosphate + acetate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Pathwayi: chitin degradation

This protein is involved in the pathway chitin degradation, which is part of Glycan degradation.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway chitin degradation and in Glycan degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi61Magnesium; via tele nitrogenUniRule annotation1
Metal bindingi126Magnesium; via pros nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Chitin degradation, Polysaccharide degradation

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

UniPathwayiUPA00349.

Names & Taxonomyi

Protein namesi
Recommended name:
Chitooligosaccharide deacetylaseUniRule annotation (EC:3.5.1.105UniRule annotation)
Short name:
CODUniRule annotation
Alternative name(s):
Chitin disaccharide deacetylaseUniRule annotation
Chitobiose deacetylaseUniRule annotation
Chitobiose-6P deacetylaseUniRule annotation
Chitotriose deacetylaseUniRule annotation
Chitotriose-6P deacetylaseUniRule annotation
Gene namesi
Name:chbGUniRule annotation
Ordered Locus Names:YPTS_3043
OrganismiYersinia pseudotuberculosis serotype IB (strain PB1/+)
Taxonomic identifieri502801 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001398401 – 253Chitooligosaccharide deacetylaseAdd BLAST253

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB2KA89.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YdjC deacetylase family. ChbG subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000225034.
KOiK03478.
OMAiEPTHIDS.

Family and domain databases

CDDicd10803. YdjC_EF3048_like. 1 hit.
Gene3Di3.20.20.370. 1 hit.
HAMAPiMF_01246. COD. 1 hit.
InterProiIPR022948. COD_ChbG_bac.
IPR011330. Glyco_hydro/deAcase_b/a-brl.
IPR002509. NODB_dom.
IPR006879. YdjC-like.
[Graphical view]
PfamiPF04794. YdjC. 1 hit.
[Graphical view]
SUPFAMiSSF88713. SSF88713. 1 hit.

Sequencei

Sequence statusi: Complete.

B2KA89-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKLLIVNAD DFGLCKGQNY GIIDAFRNGV VSSTTAMMNS VDINHAAELS
60 70 80 90 100
AQYPALPVGM HFVLTFGRPL TAMPSLTDAN GELGKWLWQR AGAGTLDLNE
110 120 130 140 150
IAQELECQFE RFSAVFGRPP THIDSHHHVH MLPQIYPLVA AFAREKSLPL
160 170 180 190 200
RIDRHEVQQH GLTLDNPRSS EWFNAGFYGE NLSEPSFLQL LEHADQQGVN
210 220 230 240 250
SLEIMCHPAF IDQTLMTSGY CYPRLTELAI LTSPTLKPAI AQRGYRLGSF

LDC
Length:253
Mass (Da):28,171
Last modified:June 10, 2008 - v1
Checksum:iE249B90C5862D0C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001048 Genomic DNA. Translation: ACC90000.1.
RefSeqiWP_002212244.1. NZ_CP009780.1.

Genome annotation databases

EnsemblBacteriaiACC90000; ACC90000; YPTS_3043.
KEGGiypb:YPTS_3043.
PATRICi18654229. VBIYerPse20639_3313.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001048 Genomic DNA. Translation: ACC90000.1.
RefSeqiWP_002212244.1. NZ_CP009780.1.

3D structure databases

ProteinModelPortaliB2KA89.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACC90000; ACC90000; YPTS_3043.
KEGGiypb:YPTS_3043.
PATRICi18654229. VBIYerPse20639_3313.

Phylogenomic databases

HOGENOMiHOG000225034.
KOiK03478.
OMAiEPTHIDS.

Enzyme and pathway databases

UniPathwayiUPA00349.

Family and domain databases

CDDicd10803. YdjC_EF3048_like. 1 hit.
Gene3Di3.20.20.370. 1 hit.
HAMAPiMF_01246. COD. 1 hit.
InterProiIPR022948. COD_ChbG_bac.
IPR011330. Glyco_hydro/deAcase_b/a-brl.
IPR002509. NODB_dom.
IPR006879. YdjC-like.
[Graphical view]
PfamiPF04794. YdjC. 1 hit.
[Graphical view]
SUPFAMiSSF88713. SSF88713. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCHBG_YERPB
AccessioniPrimary (citable) accession number: B2KA89
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 10, 2008
Last modified: November 2, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.