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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Yersinia pseudotuberculosis serotype IB (strain PB1/+)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:YPTS_0654
OrganismiYersinia pseudotuberculosis serotype IB (strain PB1/+)
Taxonomic identifieri502801 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000993421 – 289Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST289

Structurei

3D structure databases

ProteinModelPortaliB2K485.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000251871.
KOiK01525.
OMAiINAFTRM.

Family and domain databases

CDDicd07422. MPP_ApaH. 1 hit.
Gene3Di3.60.21.10. 2 hits.
HAMAPiMF_00199. ApaH. 1 hit.
InterProiIPR004617. ApaH.
IPR004843. Calcineurin-like_PHP_ApaH.
IPR029052. Metallo-depent_PP-like.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFiPIRSF000903. B5n-ttraPtase_sm. 1 hit.
SUPFAMiSSF56300. SSF56300. 1 hit.
TIGRFAMsiTIGR00668. apaH. 1 hit.

Sequencei

Sequence statusi: Complete.

B2K485-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTYLIGDIH GCLDELLALL AQVNFDPQQD TLWLTGDLVA RGPASLDVLR
60 70 80 90 100
YVRSLGPAVR MVLGNHDLHL LAVYAGISRN KPKDRITPLL DAPDADELIN
110 120 130 140 150
WLRRQPVLQV DDQLKLIMAH AGITPQWDIE TAKMCAREVE AVLSSDSYPL
160 170 180 190 200
FLDAMYGDMP NNWSPELTGL ARLRFSTNAL TRMRFCFPNG QLDMICKDTP
210 220 230 240 250
ENAPAPLKPW FDLPRLVDPE YSIIFGHWAS LEGKGVPEGI YGLDTGCCWG
260 270 280
GDLTLLRWED KRYFTQRAFK AEAEINNNNG FAAGEEVQH
Length:289
Mass (Da):32,413
Last modified:June 10, 2008 - v1
Checksum:i74C61EBA4A6A4B5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001048 Genomic DNA. Translation: ACC87638.1.
RefSeqiWP_011191708.1. NZ_CP009780.1.

Genome annotation databases

EnsemblBacteriaiACC87638; ACC87638; YPTS_0654.
KEGGiypb:YPTS_0654.
PATRICi18648916. VBIYerPse20639_0697.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001048 Genomic DNA. Translation: ACC87638.1.
RefSeqiWP_011191708.1. NZ_CP009780.1.

3D structure databases

ProteinModelPortaliB2K485.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACC87638; ACC87638; YPTS_0654.
KEGGiypb:YPTS_0654.
PATRICi18648916. VBIYerPse20639_0697.

Phylogenomic databases

HOGENOMiHOG000251871.
KOiK01525.
OMAiINAFTRM.

Family and domain databases

CDDicd07422. MPP_ApaH. 1 hit.
Gene3Di3.60.21.10. 2 hits.
HAMAPiMF_00199. ApaH. 1 hit.
InterProiIPR004617. ApaH.
IPR004843. Calcineurin-like_PHP_ApaH.
IPR029052. Metallo-depent_PP-like.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFiPIRSF000903. B5n-ttraPtase_sm. 1 hit.
SUPFAMiSSF56300. SSF56300. 1 hit.
TIGRFAMsiTIGR00668. apaH. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiAPAH_YERPB
AccessioniPrimary (citable) accession number: B2K485
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: June 10, 2008
Last modified: November 30, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.