Reviewed, UniProtKB/Swiss-Prot B2JVN8 (F16A2_BURP8)

Names and origin

Protein names

Recommended name:
    Fructose-1,6-bisphosphatase class 1 2
      Short name=FBPase class 1 2
    EC=3.1.3.11
Alternative name(s):
    D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 2

Gene names

Name:	fbp2
Ordered Locus Names:	Bphy_5951

Encoded on

Plasmid pBPHY01

Organism

Burkholderia phymatum (strain DSM 17167 / STM815) [Complete proteome] [HAMAP]

Taxonomic identifier

391038 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length	357 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855
Pathway	Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855
Subunit structure	Homotetramer By similarity.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the FBPase class 1 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome Plasmid
Gene Ontology (GO)
Biological process	carbohydrate biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	fructose 1,6-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 357	357	Fructose-1,6-bisphosphatase class 1 2 HAMAP MF_01855		PRO_0000364496
Sites
	Binding site	205	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	B2JVN8-1 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: BE60F6462CD36F09	FASTA	357	37,985
	10 20 30 40 50 60 MECAQPALSD FLADHLAPRR AQGPGVVHAA DAEGLCAVID EIAGTVKRIA ARIAQGAIGG 70 80 90 100 110 120 ARPAMPGDTA LGIAVQDLLI AMCERSAGIA GLVLPGMAAA RPTSAGRYVL FADSLDGAAN 130 140 150 160 170 180 AESNVALGTV FSIRHAGAAS ADGGCVIAGS RQLAAGYALY GPATIFVITV GRGTHGFTLC 190 200 210 220 230 240 RERGGFVLTH RSMRVPEQGA ELAVNGGNER FWEPPVQRYV SECRDGSAGV RQRDFETRWI 250 260 270 280 290 300 ASLVADTHRT LMRGGLCLLP RESRCAPRAA RQPLLYHAQA LAWLVEQAGG LASTGRARLL 310 320 330 340 350 DAAAGQDTHA RTPMFLGTRC EVERIERYHR EHERGEDLPF TSPLFNERSL FRPEARV

References

[1]

"Complete sequence of plasmid 1 of Burkholderia phymatum STM815." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Bruce D., Goodwin L., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Mikhailova N., Bacher J., Blanchard J., Cohan F., James E., Lawrence J., Lizotte-Waniewski M., Moulin L., Rainey P., Riley M., Souza V., Wertz J., Young P. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001045 Genomic DNA. Translation: ACC75015.1.
RefSeq	YP_001862061.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6247523.
GenomeReviews	Gene locus Bphy_5951 in contig CP001045_GR.
KEGG	bph:Bphy_5951.
Organism-specific databases
CMR	Search...
Family and domain databases
HAMAP	MF_01855. Divergent sequence. [Tree]
InterPro	IPR000146. Fructose_bisphosphatase. IPR020548. Fructose_bisphosphatase_AS. [Graphical view]
PANTHER	PTHR11556. In_FB_phphtase. 1 hit.
Pfam	PF00316. FBPase. 1 hit. [Graphical view]
PRINTS	PR00115. F16BPHPHTASE.
PROSITE	PS00124. FBPASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F16A2_BURP8

Accession

Primary (citable) accession number: B2JVN8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	June 10, 2008
Last modified:	September 22, 2009
This is version 10 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)