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B2JVN8 (F16A2_BURP8) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Fructose-1,6-bisphosphatase class 1 2
Short name=FBPase class 1 2
EC=3.1.3.11
Alternative name(s):
D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 2
Gene names
Name:fbp2
Ordered Locus Names:Bphy_5951
Encoded onPlasmid pBPHY01
OrganismBurkholderia phymatum (strain DSM 17167 / STM815) [Complete proteome] [HAMAP]
Taxonomic identifier391038 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length357 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855

Subunit structure

Homotetramer By similarity. HAMAP MF_01855

Subcellular location

Cytoplasm Potential HAMAP MF_01855.

Sequence similarities

Belongs to the FBPase class 1 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Cellular componentCytoplasm
   Molecular functionHydrolase
   Technical termComplete proteome
Plasmid
Gene Ontology (GO)
   Biological processcarbohydrate metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionfructose 1,6-bisphosphate 1-phosphatase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 357357Fructose-1,6-bisphosphatase class 1 2 HAMAP MF_01855
PRO_0000364496

Sites

Binding site2051Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
B2JVN8 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: BE60F6462CD36F09

FASTA35737,985
        10         20         30         40         50         60 
MECAQPALSD FLADHLAPRR AQGPGVVHAA DAEGLCAVID EIAGTVKRIA ARIAQGAIGG 

        70         80         90        100        110        120 
ARPAMPGDTA LGIAVQDLLI AMCERSAGIA GLVLPGMAAA RPTSAGRYVL FADSLDGAAN 

       130        140        150        160        170        180 
AESNVALGTV FSIRHAGAAS ADGGCVIAGS RQLAAGYALY GPATIFVITV GRGTHGFTLC 

       190        200        210        220        230        240 
RERGGFVLTH RSMRVPEQGA ELAVNGGNER FWEPPVQRYV SECRDGSAGV RQRDFETRWI 

       250        260        270        280        290        300 
ASLVADTHRT LMRGGLCLLP RESRCAPRAA RQPLLYHAQA LAWLVEQAGG LASTGRARLL 

       310        320        330        340        350 
DAAAGQDTHA RTPMFLGTRC EVERIERYHR EHERGEDLPF TSPLFNERSL FRPEARV

« Hide

References

[1]"Complete sequence of plasmid 1 of Burkholderia phymatum STM815."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Bruce D., Goodwin L., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Mikhailova N., Bacher J., Blanchard J., Cohan F., James E., Lawrence J., Lizotte-Waniewski M., Moulin L., Rainey P., Riley M., Souza V., Wertz J., Young P.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 17167 / STM815.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001045 Genomic DNA. Translation: ACC75015.1.
RefSeqYP_001862061.1. NC_010625.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB2JVN8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6247523.
GenomeReviewsGene locus Bphy_5951 in contig CP001045_GR.
KEGGbph:Bphy_5951.
PATRIC19198786. VBIBurPhy25146_6272.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG731261.
OMACEVERIE.

Family and domain databases

HAMAPMF_01855. FBPase_class1. Divergent sequence.
[Tree]
InterProIPR000146. FBPase_class-1/SBPase.
[Graphical view]
KOK03841.
PANTHERPTHR11556. In_FB_phphtase. 1 hit.
PfamPF00316. FBPase. 1 hit.
[Graphical view]
PIRSFPIRSF000904. FBPtase_SBPase. 1 hit.
PRINTSPR00115. F16BPHPHTASE.
PROSITEPS00124. FBPASE. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF16A2_BURP8
AccessionPrimary (citable) accession number: B2JVN8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: June 10, 2008
Last modified: January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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