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B2JQ19 (B2JQ19_BURP8) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable L-aspartate dehydrogenase HAMAP MF_01265
EC=1.4.1.21 HAMAP MF_01265
Gene names
Name:nadX HAMAP MF_01265
Ordered Locus Names:Bphy_4240
OrganismBurkholderia phymatum (strain DSM 17167 / STM815) [Complete proteome] [HAMAP]
Taxonomic identifier391038 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length269 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate By similarity. HAMAP MF_01265

Catalytic activity

L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H. HAMAP MF_01265

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. HAMAP MF_01265

Miscellaneous

The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia By similarity. HAMAP MF_01265

Sequence similarities

Belongs to the L-aspartate dehydrogenase family. HAMAP MF_01265

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2221 By similarity HAMAP MF_01265
Binding site1261NAD; via amide nitrogen By similarity HAMAP MF_01265
Binding site1921NAD By similarity HAMAP MF_01265

Sequences

Sequence LengthMass (Da)Tools
B2JQ19 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: 1358EC8B61EDA11F

FASTA26928,028
        10         20         30         40         50         60 
MNHVPIDIAM IGFGAIGQTV YRAVAADPQV HVSHVIVPEH QADAVREQVG PNVDVVWSVD 

        70         80         90        100        110        120 
ALKSRPQFAL ECAGHGALVS HVVPLLKAGT DCAVASIGAL SDLTLLEALH AAADEGHATV 

       130        140        150        160        170        180 
TLLSGAIGGI DALAAAKLGG LDEVQYIGRK PPTGWLGTPA EQICDLRTLT QARVIFEGSA 

       190        200        210        220        230        240 
REAARLYPKN ANVAATVALA GLGLDQTTVR LIADPAVTRN VHRIVARGAF GEMSLEMSGK 

       250        260 
PLPDNPKTSA LTAFSAIRAL RNRAARCVI

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References

[1]"Complete sequence of chromosome 2 of Burkholderia phymatum STM815."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Bruce D., Goodwin L., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Mikhailova N., Bacher J., Blanchard J., Cohan F., James E., Lawrence J., Lizotte-Waniewski M., Moulin L., Rainey P., Riley M., Souza V., Wertz J., Young P.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001044 Genomic DNA. Translation: ACC73360.1.
RefSeqYP_001860406.1. NC_010623.1.

3D structure databases

ProteinModelPortalB2JQ19.
ModBaseSearch...

Protein-protein interaction databases

STRINGB2JQ19.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6245767.
GenomeReviewsGene locus Bphy_4240 in contig CP001044_GR.
KEGGbph:Bphy_4240.
PATRIC19195179. VBIBurPhy25146_4476.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG649642.
OMAECAGHSA.
ProtClustDBPRK13303.

Family and domain databases

HAMAPMF_01265. NadX.
[Tree]
InterProIPR005106. Asp/hSer_DH_NAD-bd.
IPR002811. Asp_DH.
IPR011182. Asp_DH_NAD_syn.
IPR020626. Asp_DH_NAD_syn_prok.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK06989.
PfamPF01958. DUF108. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
PIRSFPIRSF005227. Asp_dh_NAD_syn. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB2JQ19_BURP8
AccessionPrimary (citable) accession number: B2JQ19
Entry history
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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