Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B2JIE7

- B2JIE7_BURP8

UniProt

B2JIE7 - B2JIE7_BURP8

Protein

Alanine racemase

Gene

Bphy_1359

Organism
Burkholderia phymatum (strain DSM 17167 / STM815)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 50 (01 Oct 2014)
      Sequence version 1 (10 Jun 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei42 – 421Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei137 – 1371SubstrateUniRule annotation
    Active sitei260 – 2601Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei308 – 3081Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciBPHY391038:GI4Z-1390-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Bphy_1359Imported
    OrganismiBurkholderia phymatum (strain DSM 17167 / STM815)Imported
    Taxonomic identifieri391038 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
    ProteomesiUP000001192: Chromosome 1

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei42 – 421N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi391038.Bphy_1359.

    Structurei

    3D structure databases

    ProteinModelPortaliB2JIE7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0787.
    HOGENOMiHOG000031446.
    KOiK01775.
    OMAiSRLGLWH.
    OrthoDBiEOG6PP9NJ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B2JIE7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSLRKYPMPR PVSATIHTAA LANNLAVARR YAPKSKIWAV VKANAYGHGL    50
    ARAFPGLRAT DGFGLLDLEE AVKLRELGWA GPILLLEGFF RPTDIDVIDR 100
    YSLTTALHSD EQLRMLEMAR LSKPVNIQLK MNSGMNRLGY TPEKFRAAWE 150
    RARACQGVGQ ITLMTHFSDA DSERGISHQM EAFERGAQGI AGARSLANSA 200
    ATLWYPEAHF DWVRPGVMLY GASPSGVSSA IKDTGLQPAM TLASELIAVQ 250
    TLAQGQTIGY GSTFTAREGM RIGVVACGYA DGYPRVAPEG TPIIVDGIRT 300
    RIVGRVSMDM ITVDLTPCPQ ANVGSRVELW GAQLPVDDVA QSCGTIGYEL 350
    VCAVAPRVPV RAE 363
    Length:363
    Mass (Da):39,218
    Last modified:June 10, 2008 - v1
    Checksum:i3ACCED0071EA0076
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001043 Genomic DNA. Translation: ACC70541.1.
    RefSeqiYP_001857587.1. NC_010622.1.

    Genome annotation databases

    EnsemblBacteriaiACC70541; ACC70541; Bphy_1359.
    GeneIDi6242850.
    KEGGibph:Bphy_1359.
    PATRICi19189026. VBIBurPhy25146_1445.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001043 Genomic DNA. Translation: ACC70541.1 .
    RefSeqi YP_001857587.1. NC_010622.1.

    3D structure databases

    ProteinModelPortali B2JIE7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 391038.Bphy_1359.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACC70541 ; ACC70541 ; Bphy_1359 .
    GeneIDi 6242850.
    KEGGi bph:Bphy_1359.
    PATRICi 19189026. VBIBurPhy25146_1445.

    Phylogenomic databases

    eggNOGi COG0787.
    HOGENOMi HOG000031446.
    KOi K01775.
    OMAi SRLGLWH.
    OrthoDBi EOG6PP9NJ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci BPHY391038:GI4Z-1390-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 17167 / STM815Imported.

    Entry informationi

    Entry nameiB2JIE7_BURP8
    AccessioniPrimary (citable) accession number: B2JIE7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 10, 2008
    Last sequence update: June 10, 2008
    Last modified: October 1, 2014
    This is version 50 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3