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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815) (Burkholderia phymatum)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei137GTPUniRule annotation1
Binding sitei141GTPUniRule annotation1
Binding sitei185GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi22 – 26GTPUniRule annotation5
Nucleotide bindingi106 – 108GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciBPHY391038:G1GBS-2739-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:Bphy_2668Imported
OrganismiParaburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815) (Burkholderia phymatum)Imported
Taxonomic identifieri391038 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeParaburkholderia
Proteomesi
  • UP000001192 Componenti: Chromosome 1

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi391038.Bphy_2668

Structurei

3D structure databases

ProteinModelPortaliB2JHF5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 203TubulinInterPro annotationAdd BLAST190
Domaini205 – 323Tubulin_CInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI
OrthoDBiPOG091H02KK

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

B2JHF5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEFQMLETET NGTIIKVVGV GGAGGNAVMH MINRGVQGVD FIVMNTDAQA
60 70 80 90 100
LSRSRAPNVI QLGNTGLGAG AKPEMGRAAA EEARERIADA LRGAHMVFIT
110 120 130 140 150
AGMGGGTGTG AAPVVAQIAK EMGILTVGVV SKPFEFEGGK RMRVAEAGSQ
160 170 180 190 200
QLEDHVDSLI VVLNDKLFEV MGDDAEMDKC FQCADDVLNN AVAGIAEIIN
210 220 230 240 250
VDGLVNVDFE DVKTVMGEQG KAMMGTATVA GVDRARLAAE QAVASPLLEG
260 270 280 290 300
VDLSGARGVL VNITSSRSLR LSETREVMNT IKSYAADDAT VIFGAVYDDA
310 320 330 340 350
MGDALRVTVV ATGLGRAAKK QQQTPMTLLR TGTDNQPVGA MQHVYTPQHA
360 370 380 390
ATADYGSLDT PAVWRTSRDT AASHVQALQE KGVDTYDIPA FLRKQAD
Length:397
Mass (Da):41,711
Last modified:June 10, 2008 - v1
Checksum:iD0FFCAE61E86FCC2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001043 Genomic DNA Translation: ACC71840.1
RefSeqiWP_012402040.1, NC_010622.1

Genome annotation databases

EnsemblBacteriaiACC71840; ACC71840; Bphy_2668
GeneIDi27742353
KEGGibph:Bphy_2668

Similar proteinsi

Entry informationi

Entry nameiB2JHF5_PARP8
AccessioniPrimary (citable) accession number: B2JHF5
Entry historyiIntegrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: March 28, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health