B2JHB5 (B2JHB5_BURP8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Beta-lactamase EMBL ACC70353.1
EC=3.5.2.6 EMBL ACC70353.1

Gene names

Ordered Locus Names:

Bphy_1164

Organism

Burkholderia phymatum (strain DSM 17167 / STM815) [Complete proteome] [HAMAP]

Taxonomic identifier

391038 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length	300 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

A beta-lactam + H2O = a substituted beta-amino acid. SAAS SAAS012338

Ontologies

Keywords
Biological process	Antibiotic resistance SAAS SAAS012338
Domain	Signal EMBL ACC70353.1
Molecular function	Hydrolase SAAS SAAS012338 EMBL ACC70353.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	beta-lactam antibiotic catabolic process Inferred from electronic annotation. Source: InterPro response to antibiotic Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	beta-lactamase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 32	32	Potential EMBL ACC70353.1
	Chain	33 – 300	268	Potential EMBL ACC70353.1		PRO_5000344303

Sequences

	Sequence		Length	Mass (Da)
	B2JHB5 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: 14949FB88EDE44B2	FASTA	300	31,215
	10 20 30 40 50 60 MVTRRAFTIA LGGGLAGIAV QAFGTAAAAS AQGRAAHGGA LDKRFAQIEA ETGGRLGVAI 70 80 90 100 110 120 LDTANGQLQG WRARERFPMC STFKFLLASA VLMRKDQGKE QLGRRIVYAK DAVVANSPVS 130 140 150 160 170 180 GPRAGGDGMT VSELCEAALT RSDNTAANLL LESIGGPPAL TVFARGIGDG VTRLDRNEPT 190 200 210 220 230 240 LNEAIEGDPR DTTTPAAMIA DMRAMLLGEH LSAASRQHLT VWLVANKTGD TRLRAGLPPD 250 260 270 280 290 300 WRVGDKTGTG ERGTSNDIAI VWPAGRPPVL VAVYLTGATQ TSAAQRDAAI AKVGALVAHL

References

[1]

"Complete sequence of chromosome 1 of Burkholderia phymatum STM815." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Bruce D., Goodwin L., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Mikhailova N., Bacher J., Blanchard J., Cohan F., James E., Lawrence J., Lizotte-Waniewski M., Moulin L., Rainey P., Riley M., Souza V., Wertz J., Young P. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001043 Genomic DNA. Translation: ACC70353.1.
RefSeq	YP_001857399.1. NC_010622.1.
3D structure databases
ProteinModelPortal	B2JHB5.
ModBase	Search...
Protein-protein interaction databases
STRING	B2JHB5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6242662.
GenomeReviews	Gene locus Bphy_1164 in contig CP001043_GR.
KEGG	bph:Bphy_1164.
PATRIC	19188593. VBIBurPhy25146_1234.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG535713.
OMA	ATYDNQL.
ProtClustDB	CLSK2801664.
Family and domain databases
InterPro	IPR001466. Beta-lactam-related. IPR012338. Beta-lactam/transpept-like. IPR000871. Beta-lactam_class-A/D. [Graphical view]
Gene3D	G3DSA:3.40.710.10. G3DSA:3.40.710.10. 1 hit.
KO	K01467.
Pfam	PF00144. Beta-lactamase. 1 hit. [Graphical view]
PRINTS	PR00118. BLACTAMASEA.
SUPFAM	SSF56601. PBP_transp_fold. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B2JHB5_BURP8

Accession

Primary (citable) accession number: B2JHB5

Entry history

Integrated into UniProtKB/TrEMBL:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)