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B2JGE9 (PPNK_BURP8) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable inorganic polyphosphate/ATP-NAD kinase
Short name=Poly(P)/ATP NAD kinase
EC=2.7.1.23
Gene names
Name:ppnK
Ordered Locus Names:Bphy_2504
OrganismBurkholderia phymatum (strain DSM 17167 / STM815) [Complete proteome] [HAMAP]
Taxonomic identifier391038 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length300 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP MF_00361

Cofactor

Divalent metal ions By similarity. HAMAP MF_00361

Subcellular location

Cytoplasm By similarity HAMAP MF_00361.

Sequence similarities

Belongs to the NAD kinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
NAD
NADP
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

NAD+ kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 300300Probable inorganic polyphosphate/ATP-NAD kinase HAMAP MF_00361
PRO_1000120836

Sequences

Sequence LengthMass (Da)Tools
B2JGE9 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: 18F48BC00512A61E

FASTA30032,939
        10         20         30         40         50         60 
MQANSQFKTV ALVGRSNTPG IGEPLTALAT CIEKLGFEIA FEAETAQEIG VSRWPALQPA 

        70         80         90        100        110        120 
EIGARADVAI VLGGDGTMLG IGRQLAPYKT PLIGINHGRL GFITDIPFSD MREIIPQMLS 

       130        140        150        160        170        180 
GSFEREERSL LESRIMRDGQ PIYHALAFND VVVNRSGFSG MAELRVSVDG RFMYNQRSDG 

       190        200        210        220        230        240 
LIVATPTGST AYALSSQGPI LHPQLQGLVL VPIAPHALSN RPIVIPDDSK VSIQIISGRD 

       250        260        270        280        290        300 
VNVNFDMQSF TALELNDTID VRRSRHTVPF LHPVGYSYYA TLRKKLHWNE YPSHEDDPDD

« Hide

References

[1]"Complete sequence of chromosome 1 of Burkholderia phymatum STM815."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Bruce D., Goodwin L., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Mikhailova N., Bacher J., Blanchard J., Cohan F., James E., Lawrence J., Lizotte-Waniewski M., Moulin L., Rainey P., Riley M., Souza V., Wertz J., Young P.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 17167 / STM815.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001043 Genomic DNA. Translation: ACC71677.1.
RefSeqYP_001858723.1. NC_010622.1.

3D structure databases

ProteinModelPortalB2JGE9.
ModBaseSearch...

Protein-protein interaction databases

STRINGB2JGE9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6243988.
GenomeReviewsGene locus Bphy_2504 in contig CP001043_GR.
KEGGbph:Bphy_2504.
PATRIC19191495. VBIBurPhy25146_2658.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG713904.
OMALLHLKNY.
ProtClustDBPRK02155.

Family and domain databases

HAMAPMF_00361. NAD_kinase.
[Tree]
InterProIPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017438. ATP-NAD_kinase_PpnK-typ_a/b.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. polyP/ATP_NADK_prd.
[Graphical view]
Gene3DG3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
KOK00858.
PANTHERPTHR20275. ATP_NADK. 1 hit.
PfamPF01513. NAD_kinase. 1 hit.
[Graphical view]
SUPFAMSSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPNK_BURP8
AccessionPrimary (citable) accession number: B2JGE9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 10, 2008
Last modified: January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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