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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Burkholderia phymatum (strain DSM 17167 / STM815)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei239 – 2391UniRule annotation
Active sitei681 – 6811UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciBPHY391038:GI4Z-2230-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Bphy_2180Imported
OrganismiBurkholderia phymatum (strain DSM 17167 / STM815)Imported
Taxonomic identifieri391038 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000001192 Componenti: Chromosome 1

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi391038.Bphy_2180.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2JEP0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSSGSARPA RRTTASPDAA PASAASTAKA TKAEKARKAT QALDSRKTGK
60 70 80 90 100
STKTKAIKAK APVNGASRRI KADVKPSKAI RHDAPASAVK DDGRTREDKD
110 120 130 140 150
QPLFEDIRYL GRLLGDVVRE QEGDEVFDVV ETIRQTAVRF RREDDSVAAQ
160 170 180 190 200
ALDKKLRALS PEQTVSVVRA FSYFSHLANI AEDRHRNRRH RIHDLAGSTS
210 220 230 240 250
QPGTIAHALD RLVEANAAAT PVLQQFFNDA LIVPVLTAHP TEVQRKSILD
260 270 280 290 300
AQHDIARLLA ERDQPLTARE HLQNDSLLRA RVTSLWQTRM LRDSRLTVAD
310 320 330 340 350
EIENALSYYR ATFLEEIPQL YADIEEALVE HGLDARLPPF FQMGSWIGGD
360 370 380 390 400
RDGNPNVTGE TLENAITRQA AVIFEHYLEQ VHKLGAELSV SNLLAGASDE
410 420 430 440 450
LKALAQASPD HSPHRTDEPY RRALIGMYTR LAASARVRLG EGVVPVRSAG
460 470 480 490 500
PGIPPIRAVP YGDSSEFVRD LHVLIDSLAE HHGASLATPR LSPLTRAAEV
510 520 530 540 550
FGFHLASIDL RQSSDIHEAV IAELFKRAGV ESDYAALSEA EKLRVLLAEL
560 570 580 590 600
AQPRLLRSPY VDYSNLVKSE LGVLEQARVT REKFGARAVR NYIISHTETV
610 620 630 640 650
SDLVEVMLLQ KEAGLLQGTL GSATHPARAG LMVIPLFETI PDLRNAPHIM
660 670 680 690 700
RDLLALPGID AIIENQGNEQ EVMLGYSDSN KDGGFLTSNW ELYRAELALV
710 720 730 740 750
SLFNERGITM RLFHGRGGTV GRGGGPTYQA ILSQPPGTVD GQIRLTEQGE
760 770 780 790 800
VIASKFGNPD IGRRNLETVV AATLEASLLP HGSAPKSQLP EFEETMQVLS
810 820 830 840 850
DAAMASYRAL VYETPGFTDY FFSSTPIAEI AELNIGSRPA SRKLQDPKQR
860 870 880 890 900
KIEDLRAIPW GFSWGQCRLL LTGWYGFGSA VAGWLDAAGA NMERERRLNQ
910 920 930 940 950
LRKMHKVWPF FSNLLSNMDM VLAKTDLAVA SRYAALVTDK KLRKHVFERI
960 970 980 990 1000
VAEWERTSNV LSEITGQKER LSDNPLLARS IKNRFPYLDP LNHLQVELLK
1010 1020 1030
RHRAGDTNVR VRRGIHLTIN GIAAGLRNTG
Length:1,030
Mass (Da):113,693
Last modified:June 10, 2008 - v1
Checksum:iC8418134C221BD0C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001043 Genomic DNA. Translation: ACC71355.1.
RefSeqiWP_012401561.1. NC_010622.1.
YP_001858401.1. NC_010622.1.

Genome annotation databases

EnsemblBacteriaiACC71355; ACC71355; Bphy_2180.
KEGGibph:Bphy_2180.
PATRICi19190821. VBIBurPhy25146_2321.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001043 Genomic DNA. Translation: ACC71355.1.
RefSeqiWP_012401561.1. NC_010622.1.
YP_001858401.1. NC_010622.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi391038.Bphy_2180.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACC71355; ACC71355; Bphy_2180.
KEGGibph:Bphy_2180.
PATRICi19190821. VBIBurPhy25146_2321.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciBPHY391038:GI4Z-2230-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 17167 / STM815Imported.

Entry informationi

Entry nameiB2JEP0_BURP8
AccessioniPrimary (citable) accession number: B2JEP0
Entry historyi
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: May 27, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.