ID   B2JAQ5_NOSP7            Unreviewed;      1043 AA.
AC   B2JAQ5;
DT   10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT   10-JUN-2008, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(S) {ECO:0000313|EMBL:ACC85009.1};
GN   OrderedLocusNames=Npun_AR143 {ECO:0000313|EMBL:ACC85009.1};
OS   Nostoc punctiforme (strain ATCC 29133 / PCC 73102).
OG   Plasmid pNPUN01 {ECO:0000313|EMBL:ACC85009.1,
OG   ECO:0000313|Proteomes:UP000001191}.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=63737 {ECO:0000313|EMBL:ACC85009.1, ECO:0000313|Proteomes:UP000001191};
RN   [1] {ECO:0000313|Proteomes:UP000001191}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29133 / PCC 73102 {ECO:0000313|Proteomes:UP000001191};
RC   PLASMID=Plasmid pNPUN01 {ECO:0000313|Proteomes:UP000001191};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Meeks J.C., Elhai J.,
RA   Campbell E.L., Thiel T., Longmire J., Potts M., Atlas R.;
RT   "Complete sequence of plasmid 1 of Nostoc punctiforme ATCC 29133.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001038; ACC85009.1; -; Genomic_DNA.
DR   RefSeq; WP_012413027.1; NC_010631.1.
DR   AlphaFoldDB; B2JAQ5; -.
DR   EnsemblBacteria; ACC85009; ACC85009; Npun_AR143.
DR   KEGG; npu:Npun_AR143; -.
DR   HOGENOM; CLU_000445_70_20_3; -.
DR   PhylomeDB; B2JAQ5; -.
DR   Proteomes; UP000001191; Plasmid pNPUN01.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 3.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 3.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 3.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 4.
DR   SMART; SM00091; PAS; 3.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 3.
DR   PROSITE; PS50112; PAS; 3.
PE   4: Predicted;
KW   Plasmid {ECO:0000313|EMBL:ACC85009.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001191}.
FT   DOMAIN          226..299
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          300..354
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          355..409
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          427..479
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          480..553
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          555..607
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          640..773
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          782..1038
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   1043 AA;  118077 MW;  A6DB5636A31BAAAD CRC64;
     MYQNQQTQNN LTEKSIFLNE EYLTGCNYPN RNSLPKVKEL DNQPKIDWQQ ILYSLTELSP
     FPIGIVCLES QQVLFKNELL ASFLEIEPSQ RFDKIIPSFY DQPTLWAKLV NNLKSGNLIK
     NCAVEVKKAN GDIFKAEISA KVVKYEDKLA ALFIFMNSTE HLNEHLKTQH EDFSLTAAVQ
     EIADPIDFTY SRCNLVDVNL SIVSTTNNPN VQSVEKISPL QEPEVDLHLM ERAIAASSNG
     IILTDPNQPD NPIIYVNPAF ELITGYCASE VIGRNCRFLQ GNDLEQVALQ ELRSAIQEQR
     ECHVILRNYR KDNFLFWNEL YLAPVFDNSG YLTNFIGIQT DITHHLQALE ALGKQEEQYR
     RIVQTATEGI WLLDKDNCTT FVNQQMATML GYTIEEMLGA TLFSFMDSEG LEIANSCLSR
     RYQGIQEAHD FKFRCQDGSD LWAIISCAPL LDDQGNYAGA LGMVTNITDR KLAEAALQES
     KQRLDGILCS LEDVIWSISA DTFETLYLNP AALKVYGYSV SEFFENSNLW FEVIHPEDQQ
     QVHAAIQPLF LTEKQELEYR IVRPDGQVRW LLNRSHLIYN ASGLPIRIDG IATDITERKL
     LEEKLVHNAF YDALTGLPNR ILFIDRLEQA IAQMKHNPDD LFAVLFLDLD RFKVVNDSLG
     HLVGDQLLVT LAQRLQQCLQ PDDTVARLGG DEFTILLSHI QTIEDATDIA KHIHQALKPP
     FNLCGYEVFM TASIGIALGT NKYVQPADLL RDADTALYRA KEQSQAGHIV FDTTMYDRAV
     ELLQLETDLR WAVERQELCI FYQPIICIKT GKITGFEALV RWQHPERGLI SPTEFIPVAE
     ETGLIIPIGQ WVLTESCKQL RQWQLQFPAI KPLTLNVNLS GKQFSQPHLI EQISQILQDT
     GLSSSNLKLE ITETAIIASP QKATSILKQL KAFGLQLCID DFGTGYSSLA YLHNFPIDVL
     KIDRSFVNRI DSDTEQFAIV RAIVTLADNL GMSVVAEGVE TINQLAQLQL LQCQQAQGYL
     FSKPLDQEQA RNLLASGQSF LRI
//