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B2J8Y3 (B2J8Y3_NOSP7) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrA 3 HAMAP MF_01401

Short name=Protein-methionine-S-oxide reductase 3 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401
Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 3 HAMAP MF_01401
Gene names
Name:msrA3 HAMAP MF_01401
Ordered Locus Names:Npun_R4246
OrganismNostoc punctiforme (strain ATCC 29133 / PCC 73102) [Complete proteome] [HAMAP]
Taxonomic identifier63737 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaNostocalesNostocaceaeNostoc

Protein attributes

Sequence length222 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401

Catalytic activity

L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
   Molecular functionOxidoreductase HAMAP MF_01401
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processprotein modification process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionpeptide-methionine-(S)-S-oxide reductase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site561 By similarity HAMAP MF_01401

Sequences

Sequence LengthMass (Da)Tools
B2J8Y3 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: A163DF219A1CEE51

FASTA22224,341
        10         20         30         40         50         60 
MALFGFGKKQ VMPTPEEALS GRAQSMSVPA AHYVNKNPLK APYPDGLEKA IFGLGCFWGA 

        70         80         90        100        110        120 
ERKFWQLKGV YTTAVGYAAG FTPNPTYEEV CSGRTGHNEV VLVVFDPKVI SYSELLKVFW 

       130        140        150        160        170        180 
ESHNPTQGMR QGNDAGTQYR SGIYVYSESQ KQLAEASREA YQQALNDAGY GKITTEILDA 

       190        200        210        220 
PEFYYAEAYH QQYLAKNPNG YCGLGGTNVS CPVGVVESQV SS 

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References

[1]"Complete sequence of chromosome of Nostoc punctiforme ATCC 29133."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Meeks J.C. expand/collapse author list , Elhai J., Campbell E.L., Thiel T., Longmire J., Potts M., Atlas R.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29133 / PCC 73102.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001037 Genomic DNA. Translation: ACC82621.1.
RefSeqYP_001867564.1. NC_010628.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB2J8Y3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6253590.
GenomeReviewsGene locus Npun_R4246 in contig CP001037_GR.
KEGGnpu:Npun_R4246.
PATRIC22761658. VBINosPun48114_4988.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG748152.
OMAQETSFEQ.
PhylomeDBB2J8Y3.
ProtClustDBPRK00058.

Family and domain databases

HAMAPMF_01401. MsrA.
[Tree]
InterProIPR002569. Peptide_Met_Sox_Rdtase_MsrA.
[Graphical view]
Gene3DG3DSA:3.30.1060.10. MsrA. 1 hit.
KOK07304.
PfamPF01625. PMSR. 1 hit.
[Graphical view]
SUPFAMSSF55068. MsrA. 1 hit.
TIGRFAMsTIGR00401. MsrA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB2J8Y3_NOSP7
AccessionPrimary (citable) accession number: B2J8Y3
Entry history
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)