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B2J7X1

- B2J7X1_NOSP7

UniProt

B2J7X1 - B2J7X1_NOSP7

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Protein

Alanine racemase

Gene
Npun_F5633
Organism
Nostoc punctiforme (strain ATCC 29133 / PCC 73102)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei57 – 571Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei158 – 1581Substrate By similarityUniRule annotation
Active sitei287 – 2871Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei335 – 3351Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciNPUN63737:GJNP-5497-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Npun_F5633Imported
OrganismiNostoc punctiforme (strain ATCC 29133 / PCC 73102)Imported
Taxonomic identifieri63737 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
ProteomesiUP000001191: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei57 – 571N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi63737.Npun_F5633.

Structurei

3D structure databases

ProteinModelPortaliB2J7X1.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OMAiIYSHLAL.
OrthoDBiEOG6PP9NJ.
PhylomeDBiB2J7X1.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2J7X1-1 [UniParc]FASTAAdd to Basket

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MLSRKEIPGV VPNQQCDTYA WFSQRAWVEI DLGALSYNVQ QLVQFLSPRT    50
QLMAVVKADA YGHGALTVAQ TVIQSGASWL GVATVPEAIQ LREGGIEAPI 100
LILGATHTPE QIHAIAQWNL QPTLCSPKQA LVFSNILESM NHGSPVPVHI 150
KLDTGMSRLG TNWQQAGEFV QLVQRLPHLS IASIYSHLAT ADDPDTTAME 200
EQHRRFEEAI AQIKAMEIEA PCLHLANSAA ALTDPALHYD IVRVGLAVYG 250
LYPAPHLQNA IDLKPVLQLK ARVTQVKTIA AGTAVSYGHK FIAPRELRLA 300
VVGIGYADGV PRSLSNKMQA LIHGQRVSQI GTITMDQLML DVSAIPNIQE 350
GEVVTLLGKQ GKEQISADDW AEQLNTISWE ILCGFKHRLP RVAVM 395
Length:395
Mass (Da):43,133
Last modified:June 10, 2008 - v1
Checksum:iCEA8A2F0B359BC94
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001037 Genomic DNA. Translation: ACC83936.1.
RefSeqiYP_001868879.1. NC_010628.1.

Genome annotation databases

EnsemblBacteriaiACC83936; ACC83936; Npun_F5633.
GeneIDi6254974.
KEGGinpu:Npun_F5633.
PATRICi22764876. VBINosPun48114_6572.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001037 Genomic DNA. Translation: ACC83936.1 .
RefSeqi YP_001868879.1. NC_010628.1.

3D structure databases

ProteinModelPortali B2J7X1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 63737.Npun_F5633.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACC83936 ; ACC83936 ; Npun_F5633 .
GeneIDi 6254974.
KEGGi npu:Npun_F5633.
PATRICi 22764876. VBINosPun48114_6572.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031444.
KOi K01775.
OMAi IYSHLAL.
OrthoDBi EOG6PP9NJ.
PhylomeDBi B2J7X1.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci NPUN63737:GJNP-5497-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29133 / PCC 73102.

Entry informationi

Entry nameiB2J7X1_NOSP7
AccessioniPrimary (citable) accession number: B2J7X1
Entry historyi
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: July 9, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi