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B2J7X1

- B2J7X1_NOSP7

UniProt

B2J7X1 - B2J7X1_NOSP7

Protein

Alanine racemase

Gene

Npun_F5633

Organism
Nostoc punctiforme (strain ATCC 29133 / PCC 73102)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (10 Jun 2008)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei57 – 571Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei158 – 1581SubstrateUniRule annotation
    Active sitei287 – 2871Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei335 – 3351Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciNPUN63737:GJNP-5497-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Npun_F5633Imported
    OrganismiNostoc punctiforme (strain ATCC 29133 / PCC 73102)Imported
    Taxonomic identifieri63737 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
    ProteomesiUP000001191: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei57 – 571N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi63737.Npun_F5633.

    Structurei

    3D structure databases

    ProteinModelPortaliB2J7X1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0787.
    HOGENOMiHOG000031444.
    KOiK01775.
    OMAiIYSHLAL.
    OrthoDBiEOG6PP9NJ.
    PhylomeDBiB2J7X1.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B2J7X1-1 [UniParc]FASTAAdd to Basket

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    MLSRKEIPGV VPNQQCDTYA WFSQRAWVEI DLGALSYNVQ QLVQFLSPRT    50
    QLMAVVKADA YGHGALTVAQ TVIQSGASWL GVATVPEAIQ LREGGIEAPI 100
    LILGATHTPE QIHAIAQWNL QPTLCSPKQA LVFSNILESM NHGSPVPVHI 150
    KLDTGMSRLG TNWQQAGEFV QLVQRLPHLS IASIYSHLAT ADDPDTTAME 200
    EQHRRFEEAI AQIKAMEIEA PCLHLANSAA ALTDPALHYD IVRVGLAVYG 250
    LYPAPHLQNA IDLKPVLQLK ARVTQVKTIA AGTAVSYGHK FIAPRELRLA 300
    VVGIGYADGV PRSLSNKMQA LIHGQRVSQI GTITMDQLML DVSAIPNIQE 350
    GEVVTLLGKQ GKEQISADDW AEQLNTISWE ILCGFKHRLP RVAVM 395
    Length:395
    Mass (Da):43,133
    Last modified:June 10, 2008 - v1
    Checksum:iCEA8A2F0B359BC94
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001037 Genomic DNA. Translation: ACC83936.1.
    RefSeqiYP_001868879.1. NC_010628.1.

    Genome annotation databases

    EnsemblBacteriaiACC83936; ACC83936; Npun_F5633.
    GeneIDi6254974.
    KEGGinpu:Npun_F5633.
    PATRICi22764876. VBINosPun48114_6572.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001037 Genomic DNA. Translation: ACC83936.1 .
    RefSeqi YP_001868879.1. NC_010628.1.

    3D structure databases

    ProteinModelPortali B2J7X1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 63737.Npun_F5633.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACC83936 ; ACC83936 ; Npun_F5633 .
    GeneIDi 6254974.
    KEGGi npu:Npun_F5633.
    PATRICi 22764876. VBINosPun48114_6572.

    Phylogenomic databases

    eggNOGi COG0787.
    HOGENOMi HOG000031444.
    KOi K01775.
    OMAi IYSHLAL.
    OrthoDBi EOG6PP9NJ.
    PhylomeDBi B2J7X1.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci NPUN63737:GJNP-5497-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 29133 / PCC 73102Imported.

    Entry informationi

    Entry nameiB2J7X1_NOSP7
    AccessioniPrimary (citable) accession number: B2J7X1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 10, 2008
    Last sequence update: June 10, 2008
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3