B2J6S7 (NU3C_NOSP7) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
NAD(P)H-quinone oxidoreductase subunit 3
EC=1.6.5.-

Alternative name(s):
NAD(P)H dehydrogenase subunit 3
NADH-plastoquinone oxidoreductase subunit 3
NDH-1 subunit 3
Short name=NDH-C

Gene names

Name:	ndhC
Ordered Locus Names:	Npun_R5548

Organism

Nostoc punctiforme (strain ATCC 29133 / PCC 73102) [Complete proteome] [HAMAP]

Taxonomic identifier

63737 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length	120 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration By similarity. HAMAP MF_01394
Catalytic activity	NAD(P)H + plastoquinone = NAD(P)+ + plastoquinol. HAMAP MF_01394
Subunit structure	NDH-1 can be composed of about 15 different subunits; different subcomplexes with different compositions have been identified which probably have different functions By similarity.
Subcellular location	Cellular thylakoid membrane; Multi-pass membrane protein By similarity HAMAP MF_01394.
Sequence similarities	Belongs to the complex I subunit 3 family.

Ontologies

Keywords
Biological process	Transport
Cellular component	Membrane Thylakoid
Domain	Transmembrane Transmembrane helix
Ligand	NAD NADP Plastoquinone
Molecular function	Oxidoreductase
PTM	Quinone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW thylakoid membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	NADH dehydrogenase (ubiquinone) activity Inferred from electronic annotation. Source: InterPro quinone binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 120	120	NAD(P)H-quinone oxidoreductase subunit 3 HAMAP MF_01394		PRO_0000362709
Regions
	Transmembrane	1 – 21	21	Helical; Potential
	Transmembrane	64 – 84	21	Helical; Potential
	Transmembrane	89 – 109	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	B2J6S7 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: 1EC40A0214D25CFB	FASTA	120	13,644
	10 20 30 40 50 60 MFVLSGYEYL LGFFIICSLV PALALSASKL LRPSGYAPER RTTYESGMEP IGGAWIQFNI 70 80 90 100 110 120 RYYMFALVFV VFDVETVFLY PWAVAFHRLG LLAFIEALVF IAILVVALVY AWRKGALEWS

References

[1]

"Complete sequence of chromosome of Nostoc punctiforme ATCC 29133." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Meeks J.C. , Elhai J., Campbell E.L., Thiel T., Longmire J., Potts M., Atlas R. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29133 / PCC 73102.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001037 Genomic DNA. Translation: ACC83853.1.
RefSeq	YP_001868796.1. NC_010628.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B2J6S7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6254889.
GenomeReviews	Gene locus Npun_R5548 in contig CP001037_GR.
KEGG	npu:Npun_R5548.
PATRIC	22764664. VBINosPun48114_6467.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG605540.
OMA	GERELTY.
PhylomeDB	B2J6S7.
ProtClustDB	PRK06602.
Family and domain databases
HAMAP	MF_01394. NDH1_NuoA. [Tree]
InterPro	IPR023043. NAD(P)H_OxRDtase_bac/plastid. IPR000440. NADH_UbQ/plastoQ_OxRdtase_su3. [Graphical view]
KO	K05574.
PANTHER	PTHR11058. Oxidored_q4. 1 hit.
Pfam	PF00507. Oxidored_q4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NU3C_NOSP7

Accession

Primary (citable) accession number: B2J6S7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	June 10, 2008
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program