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B2J4Z5

- B2J4Z5_NOSP7

UniProt

B2J4Z5 - B2J4Z5_NOSP7

Protein
Submitted name:

Uncharacterized protein

Gene

Npun_R2028

Organism
Nostoc punctiforme (strain ATCC 29133 / PCC 73102)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (10 Jun 2008)
      Previous versions | rss
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    Functioni

    Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.SAAS annotation

    Catalytic activityi

    1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 = 3-(methylthio)propanoate + formate + CO.SAAS annotation

    Cofactori

    Binds 1 iron ion per monomer.SAAS annotation
    Binds 1 nickel ion per monomer.SAAS annotation

    GO - Molecular functioni

    1. acireductone dioxygenase [iron(II)-requiring] activity Source: InterPro
    2. metal ion binding Source: UniProtKB-KW

    Keywords - Ligandi

    IronSAAS annotation, Metal-bindingSAAS annotation, NickelSAAS annotation

    Enzyme and pathway databases

    BioCyciNPUN63737:GJNP-1972-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Ordered Locus Names:Npun_R2028Imported
    OrganismiNostoc punctiforme (strain ATCC 29133 / PCC 73102)Imported
    Taxonomic identifieri63737 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
    ProteomesiUP000001191: Chromosome

    Interactioni

    Subunit structurei

    Monomer.SAAS annotation

    Protein-protein interaction databases

    STRINGi63737.Npun_R2028.

    Structurei

    3D structure databases

    ProteinModelPortaliB2J4Z5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG1791.
    HOGENOMiHOG000201072.
    KOiK08967.
    OMAiYGRYHTH.
    OrthoDBiEOG6ZPT06.
    PhylomeDBiB2J4Z5.

    Family and domain databases

    Gene3Di2.60.120.10. 1 hit.
    InterProiIPR004313. Acireductn_dOase_family.
    IPR014710. RmlC-like_jellyroll.
    IPR011051. RmlC_Cupin.
    [Graphical view]
    PfamiPF03079. ARD. 1 hit.
    [Graphical view]
    SUPFAMiSSF51182. SSF51182. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B2J4Z5-1 [UniParc]FASTAAdd to Basket

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    MANLLLDDGT IESDLGEIAR ELAPFGIQLR HYNPGTSLLF PNLLSQDVLT    50
    ESEKHYCVEL HNSVFEFLQQ ENGAIWCDLL NVHPGSFNLH HLIATYGRYH 100
    THPAPEPLYV LAGEMIYGFV RPDGSQVQLL VQAQDYLYIP ADVEHWCSPT 150
    ASLNFKAVRY FAIAEGWVPN YTGTQVSDSL NKPG 184
    Length:184
    Mass (Da):20,645
    Last modified:June 10, 2008 - v1
    Checksum:iF9A2C2586A41DAF0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001037 Genomic DNA. Translation: ACC80655.1.
    RefSeqiYP_001865598.1. NC_010628.1.

    Genome annotation databases

    EnsemblBacteriaiACC80655; ACC80655; Npun_R2028.
    GeneIDi6251448.
    KEGGinpu:Npun_R2028.
    PATRICi22756282. VBINosPun48114_2333.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001037 Genomic DNA. Translation: ACC80655.1 .
    RefSeqi YP_001865598.1. NC_010628.1.

    3D structure databases

    ProteinModelPortali B2J4Z5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 63737.Npun_R2028.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACC80655 ; ACC80655 ; Npun_R2028 .
    GeneIDi 6251448.
    KEGGi npu:Npun_R2028.
    PATRICi 22756282. VBINosPun48114_2333.

    Phylogenomic databases

    eggNOGi COG1791.
    HOGENOMi HOG000201072.
    KOi K08967.
    OMAi YGRYHTH.
    OrthoDBi EOG6ZPT06.
    PhylomeDBi B2J4Z5.

    Enzyme and pathway databases

    BioCyci NPUN63737:GJNP-1972-MONOMER.

    Family and domain databases

    Gene3Di 2.60.120.10. 1 hit.
    InterProi IPR004313. Acireductn_dOase_family.
    IPR014710. RmlC-like_jellyroll.
    IPR011051. RmlC_Cupin.
    [Graphical view ]
    Pfami PF03079. ARD. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51182. SSF51182. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 29133 / PCC 73102Imported.

    Entry informationi

    Entry nameiB2J4Z5_NOSP7
    AccessioniPrimary (citable) accession number: B2J4Z5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 10, 2008
    Last sequence update: June 10, 2008
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3