ID   B2J4I4_NOSP7            Unreviewed;       611 AA.
AC   B2J4I4;
DT   10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT   10-JUN-2008, sequence version 1.
DT   27-MAR-2024, entry version 80.
DE   SubName: Full=Response regulator receiver modulated diguanylate cyclase/phosphodiesterase {ECO:0000313|EMBL:ACC83674.1};
DE            EC=3.1.1.61 {ECO:0000313|EMBL:ACC83674.1};
GN   OrderedLocusNames=Npun_F5361 {ECO:0000313|EMBL:ACC83674.1};
OS   Nostoc punctiforme (strain ATCC 29133 / PCC 73102).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=63737 {ECO:0000313|EMBL:ACC83674.1, ECO:0000313|Proteomes:UP000001191};
RN   [1] {ECO:0000313|Proteomes:UP000001191}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29133 / PCC 73102 {ECO:0000313|Proteomes:UP000001191};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Meeks J.C., Elhai J.,
RA   Campbell E.L., Thiel T., Longmire J., Potts M., Atlas R.;
RT   "Complete sequence of chromosome of Nostoc punctiforme ATCC 29133.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ACC83674.1, ECO:0000313|Proteomes:UP000001191}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29133 / PCC 73102 {ECO:0000313|Proteomes:UP000001191};
RX   PubMed=23463784; DOI=10.1104/pp.112.213116;
RA   Ekman M., Picossi S., Campbell E.L., Meeks J.C., Flores E.;
RT   "A Nostoc punctiforme Sugar Transporter Necessary to Establish a
RT   Cyanobacterium-Plant Symbiosis.";
RL   Plant Physiol. 161:1984-1992(2013).
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DR   EMBL; CP001037; ACC83674.1; -; Genomic_DNA.
DR   RefSeq; WP_012411624.1; NC_010628.1.
DR   AlphaFoldDB; B2J4I4; -.
DR   STRING; 63737.Npun_F5361; -.
DR   EnsemblBacteria; ACC83674; ACC83674; Npun_F5361.
DR   KEGG; npu:Npun_F5361; -.
DR   eggNOG; COG2200; Bacteria.
DR   eggNOG; COG3706; Bacteria.
DR   HOGENOM; CLU_000445_70_50_3; -.
DR   OrthoDB; 9787983at2; -.
DR   PhylomeDB; B2J4I4; -.
DR   Proteomes; UP000001191; Chromosome.
DR   GO; GO:0008984; F:protein-glutamate methylesterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd19920; REC_PA4781-like; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrolase {ECO:0000313|EMBL:ACC83674.1};
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001191}.
FT   DOMAIN          12..128
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   DOMAIN          211..344
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          353..609
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
FT   COILED          141..175
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   MOD_RES         61
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   611 AA;  69722 MW;  E897350100EF2417 CRC64;
     MNYEHLDPNK KDILIVDDMA DNLRVLSSIL AREGYNVRKA LNWQMALTAT QTVLPDLILL
     DIMMPEVDGY EICQAFKAWE LTADIPVIFI SALDDVFDKV KAFRVGGVDY ITKPFEFQEV
     LVRVKNQLAL RSARLEILKL NVELEHRVTQ RTEELEKALQ KLQKEINSRQ KLQSKLLDIA
     LHDSLTGLPN RVLFMRRLDN ALNRAKQESS YQFAVLFLDC DRFKVVNDSL GHLVGDELLI
     SIARRLQACL IPIDTLARLG GDEFGILLEK ITDINIAIQV ADRILQQLSL AFKLSRYEVF
     MNASIGISWG NKDYDRPEYL LRDADTAMYR AKAQGRAKYH VFNPAMHQEA IQLLELENDL
     RRAVERQEFL VYYQPIVSLI TGKISGFEAL VRWQHPTRGL VSPTEFIPVA EETGLINAIN
     TWVLQSACHQ LSIWQHQPVT PEPLTISVNL SARLFLQPNF VEQIDRIIYE TKINPTYLEL
     EITESVIMEN TNAIKIIFQQ LKQRSIKLVM DDFGTGYSSL SYLHSFPLNA LKIDKSFVKR
     MQDNKENMGL VPAMIGIANS MGMSAIAEGV ETEEQLAQLR SLNCNFAQGF LFSEPIEQQL
     VIKLLAVAPQ W
//