ID   B2J4B3_NOSP7            Unreviewed;       570 AA.
AC   B2J4B3;
DT   10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT   10-JUN-2008, sequence version 1.
DT   27-MAR-2024, entry version 67.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase {ECO:0000313|EMBL:ACC83603.1};
GN   OrderedLocusNames=Npun_R5282 {ECO:0000313|EMBL:ACC83603.1};
OS   Nostoc punctiforme (strain ATCC 29133 / PCC 73102).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=63737 {ECO:0000313|EMBL:ACC83603.1, ECO:0000313|Proteomes:UP000001191};
RN   [1] {ECO:0000313|Proteomes:UP000001191}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29133 / PCC 73102 {ECO:0000313|Proteomes:UP000001191};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Meeks J.C., Elhai J.,
RA   Campbell E.L., Thiel T., Longmire J., Potts M., Atlas R.;
RT   "Complete sequence of chromosome of Nostoc punctiforme ATCC 29133.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ACC83603.1, ECO:0000313|Proteomes:UP000001191}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29133 / PCC 73102 {ECO:0000313|Proteomes:UP000001191};
RX   PubMed=23463784; DOI=10.1104/pp.112.213116;
RA   Ekman M., Picossi S., Campbell E.L., Meeks J.C., Flores E.;
RT   "A Nostoc punctiforme Sugar Transporter Necessary to Establish a
RT   Cyanobacterium-Plant Symbiosis.";
RL   Plant Physiol. 161:1984-1992(2013).
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DR   EMBL; CP001037; ACC83603.1; -; Genomic_DNA.
DR   RefSeq; WP_012411554.1; NC_010628.1.
DR   AlphaFoldDB; B2J4B3; -.
DR   STRING; 63737.Npun_R5282; -.
DR   EnsemblBacteria; ACC83603; ACC83603; Npun_R5282.
DR   KEGG; npu:Npun_R5282; -.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_50_3; -.
DR   OrthoDB; 9787983at2; -.
DR   PhylomeDB; B2J4B3; -.
DR   Proteomes; UP000001191; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001191};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        27..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        60..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          165..299
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          308..562
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   570 AA;  63598 MW;  330EC01E048233C0 CRC64;
     MNFNQNLYLY SFLANFGWLK KSYTAKIMLV AFLGTHVPLL TLLLSFVISN SYSFGMAARV
     IIIALLATLA GTAVTLYALN HLLKPVILTS GALQNYLNTK TLPKLPTEFA DEAGTLMADT
     SQTLHKLDEL IHQITNYDDL TGLPNRDLFR DRLHQILSQP ENNQRLVAVF LLSIDDFTGM
     SHGLDHQTTN LLLRAVAKRL LDCTAQTDVL AYLKGDEFAL ARMDIHSLES VIKLSQVLLS
     NLSKPFSVEG NLIHITVSIG ITLNNLTDPN SVAQLLQQAH IALYQAKQQG RSQYQFYSPE
     INAQLQERLT LENELHGALE RGEMLVYYQP LIDLHSGQVI AMEALIRWQH PTLGLVSPVK
     FIPIAEANGA IVPIGEWVLR TACAQTRAWQ LAGFTPIRIS VNLSSRQFEQ PYLVEIVNQI
     LEETGLQASS LELEVTKSFL MADIDRSVKT LKQLRELGIC LALDDFGTGY SSLNYLKRFP
     VNMLKIDKSF VQDVMSNPDS AAVTNAIIAL AKSLRLKITA EGVETQEQLE YLKMRGCDEG
     QGFYFSRPVP ADIIAPMLQK SSQQMEISTR
//