ID   B2J301_NOSP7            Unreviewed;       824 AA.
AC   B2J301;
DT   10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT   10-JUN-2008, sequence version 1.
DT   27-MAR-2024, entry version 84.
DE   SubName: Full=Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:ACC82068.1};
GN   OrderedLocusNames=Npun_F3678 {ECO:0000313|EMBL:ACC82068.1};
OS   Nostoc punctiforme (strain ATCC 29133 / PCC 73102).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=63737 {ECO:0000313|EMBL:ACC82068.1, ECO:0000313|Proteomes:UP000001191};
RN   [1] {ECO:0000313|Proteomes:UP000001191}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29133 / PCC 73102 {ECO:0000313|Proteomes:UP000001191};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Meeks J.C., Elhai J.,
RA   Campbell E.L., Thiel T., Longmire J., Potts M., Atlas R.;
RT   "Complete sequence of chromosome of Nostoc punctiforme ATCC 29133.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ACC82068.1, ECO:0000313|Proteomes:UP000001191}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29133 / PCC 73102 {ECO:0000313|Proteomes:UP000001191};
RX   PubMed=23463784; DOI=10.1104/pp.112.213116;
RA   Ekman M., Picossi S., Campbell E.L., Meeks J.C., Flores E.;
RT   "A Nostoc punctiforme Sugar Transporter Necessary to Establish a
RT   Cyanobacterium-Plant Symbiosis.";
RL   Plant Physiol. 161:1984-1992(2013).
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DR   EMBL; CP001037; ACC82068.1; -; Genomic_DNA.
DR   AlphaFoldDB; B2J301; -.
DR   STRING; 63737.Npun_F3678; -.
DR   EnsemblBacteria; ACC82068; ACC82068; Npun_F3678.
DR   KEGG; npu:Npun_F3678; -.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_20_3; -.
DR   OrthoDB; 9787983at2; -.
DR   PhylomeDB; B2J301; -.
DR   Proteomes; UP000001191; Chromosome.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 2.
DR   CDD; cd17534; REC_DC-like; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 2.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 2.
DR   SMART; SM00091; PAS; 2.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 2.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001191}.
FT   DOMAIN          5..120
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   DOMAIN          132..205
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          210..262
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          263..318
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          421..554
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          563..819
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
FT   MOD_RES         55
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   824 AA;  92446 MW;  CF201D3AAE671AEA CRC64;
     MNPVNILVVE DEIIVAMDIQ SRLSKFGYTV LGLADSGEEA IKKAADDSLD LVLMDIHLKG
     KMDGVEAAQI IHNIFNVPII YLTANADEST LARAKVTEPF GYILKPFKEK ELKFTIEITL
     SKHRTEKKIK QNEQWLTTVL KSIGDAVITS DASGTVTFMN PIAEELTGWN YSDAFGKEAT
     EVFNIAHEET RIIIESPITQ VLQSGITVGL PEQTILITKN GAEIPIDDSI AAIKDDNGNI
     TGAVLVFQDI TERKQILAAL ARRQQEFKAL VENAPDIISR FNTQLRYVYV NPAIEKVTGI
     SAETFIGKTN AELNLPEEFC RMCDRKLGQV FQTKQETEFE CTLAIAAQTR HYHTRLVPEL
     ASDESVYFVL SISRNITALK LAEAQLIHDA FHDILTSLPN RALFMERLER ALMLAKRRAD
     YTFAVLFLDL DRFKVVNDSL GHMIGDQLLT ALARRLENCV RAGDTVARLG GDEFTILLDD
     INNINDAIGV VERIHEALTS AFTLSGYEVF TTVSIGIVVS KGSYNLPEQI LRDADIAMYR
     AKALGKARHE IFDSTMYTQI TKLLELEMDL RRAVERQEFQ VYYQPIVLLE TCKIIGFEAL
     VRWQHPQHGL VPPESFIPIA EETGLIIPLG YWVLGEACRQ MRAWQIQFPT DPPLTISVNL
     STKQFLQPDL IEQINQIMQE TALEASNLKL EITESVLMEN IQSATFMLLQ LQQMNIQLHL
     DDFGIGYSSL SYLHRFPSHA LKIDRSFITK IGANGENLEI VQAIITLAES LNIDVIAEGI
     ETVEQLSQLR AMKCKYAQGY FFSQPLDSKS IETLIVSGIQ PRQG
//