ID   B2J1V8_NOSP7            Unreviewed;       720 AA.
AC   B2J1V8;
DT   10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT   10-JUN-2008, sequence version 1.
DT   27-MAR-2024, entry version 81.
DE   SubName: Full=Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:ACC81960.1};
GN   OrderedLocusNames=Npun_R3564 {ECO:0000313|EMBL:ACC81960.1};
OS   Nostoc punctiforme (strain ATCC 29133 / PCC 73102).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=63737 {ECO:0000313|EMBL:ACC81960.1, ECO:0000313|Proteomes:UP000001191};
RN   [1] {ECO:0000313|Proteomes:UP000001191}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29133 / PCC 73102 {ECO:0000313|Proteomes:UP000001191};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Meeks J.C., Elhai J.,
RA   Campbell E.L., Thiel T., Longmire J., Potts M., Atlas R.;
RT   "Complete sequence of chromosome of Nostoc punctiforme ATCC 29133.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ACC81960.1, ECO:0000313|Proteomes:UP000001191}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29133 / PCC 73102 {ECO:0000313|Proteomes:UP000001191};
RX   PubMed=23463784; DOI=10.1104/pp.112.213116;
RA   Ekman M., Picossi S., Campbell E.L., Meeks J.C., Flores E.;
RT   "A Nostoc punctiforme Sugar Transporter Necessary to Establish a
RT   Cyanobacterium-Plant Symbiosis.";
RL   Plant Physiol. 161:1984-1992(2013).
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DR   EMBL; CP001037; ACC81960.1; -; Genomic_DNA.
DR   RefSeq; WP_012409932.1; NC_010628.1.
DR   AlphaFoldDB; B2J1V8; -.
DR   STRING; 63737.Npun_R3564; -.
DR   EnsemblBacteria; ACC81960; ACC81960; Npun_R3564.
DR   KEGG; npu:Npun_R3564; -.
DR   eggNOG; COG2204; Bacteria.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_50_3; -.
DR   OrthoDB; 9787983at2; -.
DR   PhylomeDB; B2J1V8; -.
DR   Proteomes; UP000001191; Chromosome.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   CDD; cd00156; REC; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   PANTHER; PTHR33121:SF85; CYCLIC DI-GMP PHOSPHODIESTERASE PDEK-RELATED; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001191}.
FT   DOMAIN          6..122
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   DOMAIN          212..263
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          310..443
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          452..714
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
FT   MOD_RES         57
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   720 AA;  81773 MW;  4651018C96D4359A CRC64;
     MNEPLNILIV EDSEEDAMLV IHELCRGGFN PNWQRVQTDK ELQIALNSQT WDVMISDYRL
     PGFNASAALE IAKQSQKDIP FILVSGTIGE VLAVEMMKAG ANDYVMKDNL NRLPEAVRRE
     LRDAQVRAER KQAQKLLQTL ASNIPGMIYS FVQYSDGSIA FDYISFGCLD LLELTPDQIL
     ENASLCFAQI HPDDYPGCYA AANESAQTLK PFSYEWRLVT PSGKLKWVQA SARPECRENG
     DIVWYGVLLD VNERQVALRE QQAALRERKQ AQELIIHNSL HDPLTDLPNR TLLIERLELA
     INRAKRLETY RYAVLFLDLD RFKVINDSLG HLAGDQLLKN IAHKLKTHLR EVDLVARIGG
     DEFVILLEDI SDIEKAIQIT ERMLIDFQTP LMLNDAEVVI STSIGIVLGT NEYSQASDLL
     RDADIAMYKA KAQRRNSYKI FDVKMHTQAV NRLTIETDIR KAIEREEFVI YYQPIVDILG
     DGQSKAGRLI GFEALLRWQH PTRGLVLPKE FVSIAEETGL IVQIDRWMLY KACQHLADWK
     VKFATHFPIK VNINLSVQDI RQGNLIEYID QILAQIGLEG DCITLEITES MLIENISQTI
     DLLSQLKSRK IKISIDDFGT GYSSLNYLHR LPADNLKIDR SFVSQMQQGN RNYQVVSTII
     ALSNQLGLAV VAEGIETPQQ LQWLQELGCE FGQGYLFSKP LSHQTVEALL TTSKILHYIL
//