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B2IYE4 (AROA_NOSP7) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:Npun_F1315
OrganismNostoc punctiforme (strain ATCC 29133 / PCC 73102) [Complete proteome] [HAMAP]
Taxonomic identifier63737 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length426 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4264263-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000099734

Sequences

Sequence LengthMass (Da)Tools
B2IYE4 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: FEAB29F3C1B86767

FASTA42646,733
        10         20         30         40         50         60 
MDTIEIPALN RPVDATVEIP GSKSLTNRAL LVAALAQGDS ILENALFSED SEYFAKCLEQ 

        70         80         90        100        110        120 
LGIPITLNPH LAQIQLAGRG GEIPAKQADL FVGLSGTTAR FISALVALGN GEYRLDGVPR 

       130        140        150        160        170        180 
MRERPMGDML TVLETGGATV NFEGNSGFMP YTVYSQGFAG GNFCLKANQT SQQLSALLMI 

       190        200        210        220        230        240 
APYAQQDTIF EVEGTLVSLS YIKMTCRLMA DFGVEVIQIG DNQFQIKAGQ RYQAQHYTVE 

       250        260        270        280        290        300 
PDASNASYFF AAAAVTGGRV RVKHLTKQSC QGDILWLNVL EQMGCQIKDS DDYTEVTGPK 

       310        320        330        340        350        360 
QLQGIDIDMN DISDLVQTLA AIAPFASSPI TIRNVEHIRY KETDRIKAVV TELRRLGVQV 

       370        380        390        400        410        420 
EEFPDRLKIE PGPITPAEIE TYHDHRMAMA FAVTGLKVPG IVIKDPGCTA KTFPDYFTRF 


FQMLEQ

« Hide

References

[1]"Complete sequence of chromosome of Nostoc punctiforme ATCC 29133."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Meeks J.C. expand/collapse author list , Elhai J., Campbell E.L., Thiel T., Longmire J., Potts M., Atlas R.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29133 / PCC 73102.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001037 Genomic DNA. Translation: ACC80031.1.
RefSeqYP_001864974.1. NC_010628.1.

3D structure databases

ProteinModelPortalB2IYE4.
ModBaseSearch...

Protein-protein interaction databases

STRINGB2IYE4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6250769.
GenomeReviewsGene locus Npun_F1315 in contig CP001037_GR.
KEGGnpu:Npun_F1315.
PATRIC22754599. VBINosPun48114_1502.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646626.
OMAGADIEWG.
PhylomeDBB2IYE4.
ProtClustDBPRK02427.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_NOSP7
AccessionPrimary (citable) accession number: B2IYE4
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: June 10, 2008
Last modified: January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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