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B2IYB6 (B2IYB6_NOSP7) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 2 HAMAP MF_01840

Short name=Mg-protoporphyrin IX monomethyl ester oxidative cyclase 2 HAMAP MF_01840
EC=1.14.13.81 HAMAP MF_01840
Gene names
Name:acsF2 HAMAP MF_01840
Ordered Locus Names:Npun_F6446
OrganismNostoc punctiforme (strain ATCC 29133 / PCC 73102) [Complete proteome] [HAMAP]
Taxonomic identifier63737 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaNostocalesNostocaceaeNostoc

Protein attributes

Sequence length358 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) By similarity. HAMAP MF_01840

Catalytic activity

131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O. HAMAP MF_01840

131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = divinylprotochlorophyllide + NADP+ + 2 H2O. HAMAP MF_01840

Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O. HAMAP MF_01840

Cofactor

Iron By similarity. HAMAP MF_01840

Pathway

Porphyrin biosynthesis; chlorophyll biosynthesis (light-independent). HAMAP MF_01840

Sequence similarities

Belongs to the AcsF family. HAMAP MF_01840

Sequences

Sequence LengthMass (Da)Tools
B2IYB6 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: 5603A146673F0710

FASTA35842,419
        10         20         30         40         50         60 
MVDSLKKPGF EEIRPGIKVP AKETLLTPRF YTTDFDEMAR MDISVNEDEL QAILEEFRTD 

        70         80         90        100        110        120 
YNRHHFVRDA EFEQSWDHID GETRKLFVEF LERSCTAEFS GFLLYKELGR RLKGKSPVLA 

       130        140        150        160        170        180 
ECFNLMSRDE ARHAGFLNKA LSDFNLSLDL GFLTKSRNYT FFKPKFIFYA TYLSEKIGYW 

       190        200        210        220        230        240 
RYITIYRHLE AHPEDRVYPI FRFFENWCQD ENRHGDFFDA IMKSQPQILN DWKARLWSRF 

       250        260        270        280        290        300 
FLLSVFATMY LNDIQRKDFY ATLGLDAREY DIHVIQKTNE NAGRVFPLML DVENPEFYQR 

       310        320        330        340        350 
LDTCISNNEK LGAIANSNTP KFLQLFQKLP LYISNGWQLL RLYLMKPIDT VSAQGAVR 

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References

[1]"Complete sequence of chromosome of Nostoc punctiforme ATCC 29133."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Meeks J.C. expand/collapse author list , Elhai J., Campbell E.L., Thiel T., Longmire J., Potts M., Atlas R.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29133 / PCC 73102.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001037 Genomic DNA. Translation: ACC84715.1.
RefSeqYP_001869658.1. NC_010628.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB2IYB6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6255789.
GenomeReviewsGene locus Npun_F6446 in contig CP001037_GR.
KEGGnpu:Npun_F6446.
PATRIC22766879. VBINosPun48114_7560.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG284843.
OMAHGDFFDA.
PhylomeDBB2IYB6.
ProtClustDBPRK13654.

Family and domain databases

HAMAPMF_01840. AcsF.
[Tree]
InterProIPR008434. AcsF.
IPR009078. Ferritin/RR-like.
IPR003251. Rubrerythrin.
[Graphical view]
KOK04035.
PfamPF02915. Rubrerythrin. 1 hit.
[Graphical view]
SUPFAMSSF47240. Ferritin/RR_like. 1 hit.
TIGRFAMsTIGR02029. AcsF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB2IYB6_NOSP7
AccessionPrimary (citable) accession number: B2IYB6
Entry history
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)