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Protein

16S rRNA (cytosine(967)-C(5))-methyltransferase

Gene

Npun_F4644

Organism
Nostoc punctiforme (strain ATCC 29133 / PCC 73102)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.SAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei323S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei350S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei367S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei420NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotation, RNA-bindingPROSITE-ProRule annotationSAAS annotation, Transferase
Biological processrRNA processingSAAS annotation
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
16S rRNA (cytosine(967)-C(5))-methyltransferaseSAAS annotation (EC:2.1.1.176SAAS annotation)
Gene namesi
Ordered Locus Names:Npun_F4644Imported
OrganismiNostoc punctiforme (strain ATCC 29133 / PCC 73102)Imported
Taxonomic identifieri63737 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
Proteomesi
  • UP000001191 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi63737.Npun_F4644

Structurei

3D structure databases

ProteinModelPortaliB2IXU2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini208 – 483SAM_MT_RSMB_NOPInterPro annotationAdd BLAST276

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni299 – 305S-adenosyl-L-methionine bindingPROSITE-ProRule annotation7

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili322 – 342Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105CYJ Bacteria
COG0144 LUCA
HOGENOMiHOG000037300
KOiK03500
OMAiLRVNRQH
OrthoDBiPOG091H02E2
PhylomeDBiB2IXU2

Family and domain databases

Gene3Di1.10.940.10, 1 hit
InterProiView protein in InterPro
IPR001678 MeTrfase_RsmB/NOP2
IPR035926 NusB-like_sf
IPR006027 NusB_RsmB_TIM44
IPR023267 RCMT
IPR004573 rRNA_ssu_MeTfrase_B
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF01189 Methyltr_RsmB-F, 1 hit
PF01029 NusB, 1 hit
PRINTSiPR02008 RCMTFAMILY
SUPFAMiSSF48013 SSF48013, 1 hit
SSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR00563 rsmB, 1 hit
PROSITEiView protein in PROSITE
PS51686 SAM_MT_RSMB_NOP, 1 hit

Sequencei

Sequence statusi: Complete.

B2IXU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTNPRQLAFI ALRDVHKGAY ADVALDRVLQ KVNLPDRDRR LVTELVYGSV
60 70 80 90 100
RRQRTLDTLI DQFAKNKSHQ QPQDLRTILH LGFYQLRYQE RIPASAAVNT
110 120 130 140 150
TVQLAKENGF SGLTGFVNGL LRQYLRKAGE QGGRGAGGQR SRGAEEKDSL
160 170 180 190 200
LVPVPQPPVP STQAPVLNFD PLQLPENPVE RLGILHSFPD WIIQVWLEQL
210 220 230 240 250
GLTETEQLCE WMNQSPTIDL RINPLCTSIE EVEAALQSVG LLVRRIPDLP
260 270 280 290 300
QALRFMGNTG SIQKLPGFKE GWWTVQDASA QLVSHLLDPQ PGEVVIDVCA
310 320 330 340 350
APGGKTTHIA ELMADSGKIW ACDRTASRLR KLQENSQRLN LQSIQIYTGD
360 370 380 390 400
SRHSNQFQNT ADRVLLDAPC SGLGTMHRHA DARWRQTPES VRELSVLQKE
410 420 430 440 450
LLTHTSTFVK AGGVLVYATC TLHPAENEEV ISAFLAESPH WQIEPPRGIE
460 470 480
LAASAYSTPQ GWFKVWPHRQ DMDGFLMVRL RKTNNSE
Length:487
Mass (Da):54,522
Last modified:June 10, 2008 - v1
Checksum:i9853DC301C93D405
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001037 Genomic DNA Translation: ACC83001.1

Genome annotation databases

EnsemblBacteriaiACC83001; ACC83001; Npun_F4644
KEGGinpu:Npun_F4644

Similar proteinsi

Entry informationi

Entry nameiB2IXU2_NOSP7
AccessioniPrimary (citable) accession number: B2IXU2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: May 23, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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