ID   B2IU72_NOSP7            Unreviewed;       409 AA.
AC   B2IU72;
DT   10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT   10-JUN-2008, sequence version 1.
DT   27-MAR-2024, entry version 75.
DE   SubName: Full=Response regulator receiver modulated metal dependent phosphohydrolase {ECO:0000313|EMBL:ACC79643.1};
DE            EC=3.1.1.61 {ECO:0000313|EMBL:ACC79643.1};
GN   OrderedLocusNames=Npun_F0906 {ECO:0000313|EMBL:ACC79643.1};
OS   Nostoc punctiforme (strain ATCC 29133 / PCC 73102).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=63737 {ECO:0000313|EMBL:ACC79643.1, ECO:0000313|Proteomes:UP000001191};
RN   [1] {ECO:0000313|Proteomes:UP000001191}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29133 / PCC 73102 {ECO:0000313|Proteomes:UP000001191};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Meeks J.C., Elhai J.,
RA   Campbell E.L., Thiel T., Longmire J., Potts M., Atlas R.;
RT   "Complete sequence of chromosome of Nostoc punctiforme ATCC 29133.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ACC79643.1, ECO:0000313|Proteomes:UP000001191}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29133 / PCC 73102 {ECO:0000313|Proteomes:UP000001191};
RX   PubMed=23463784; DOI=10.1104/pp.112.213116;
RA   Ekman M., Picossi S., Campbell E.L., Meeks J.C., Flores E.;
RT   "A Nostoc punctiforme Sugar Transporter Necessary to Establish a
RT   Cyanobacterium-Plant Symbiosis.";
RL   Plant Physiol. 161:1984-1992(2013).
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DR   EMBL; CP001037; ACC79643.1; -; Genomic_DNA.
DR   RefSeq; WP_012407665.1; NC_010628.1.
DR   AlphaFoldDB; B2IU72; -.
DR   STRING; 63737.Npun_F0906; -.
DR   EnsemblBacteria; ACC79643; ACC79643; Npun_F0906.
DR   KEGG; npu:Npun_F0906; -.
DR   eggNOG; COG3437; Bacteria.
DR   HOGENOM; CLU_000445_92_10_3; -.
DR   OrthoDB; 9804747at2; -.
DR   PhylomeDB; B2IU72; -.
DR   Proteomes; UP000001191; Chromosome.
DR   GO; GO:0008984; F:protein-glutamate methylesterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   CDD; cd00077; HDc; 1.
DR   CDD; cd17538; REC_D1_PleD-like; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR037522; HD_GYP_dom.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   PANTHER; PTHR45228:SF1; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186; 1.
DR   PANTHER; PTHR45228; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186-RELATED; 1.
DR   Pfam; PF13487; HD_5; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00471; HDc; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR   PROSITE; PS51832; HD_GYP; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ACC79643.1};
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001191}.
FT   DOMAIN          96..212
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   DOMAIN          220..409
FT                   /note="HD-GYP"
FT                   /evidence="ECO:0000259|PROSITE:PS51832"
FT   MOD_RES         145
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   409 AA;  46241 MW;  B1531CC1D6FB7D53 CRC64;
     MIQWKSNHTG FTEQIVSESN PISTVKSIGS NHVVESQNNV EAYSLGLSQE DLMLENRQAV
     SSWIKSDINC GDDSLVSRTL QAKGSKVNRF DLDPPKVLVV DDHAASRMTA VALLGMEGYE
     VIEADRGSTV VGLVTQKQPD LILLDVMMPG MDGFEVCQLL KQDEQTRLIP VIFITALNDR
     RSRIRGIEVG ADDFLTKPFD RVELAARVKS LVRQKRLNED LDHAEQVLFS IAMSIESRDP
     NTGNHCERLV KLGQLFGEYL NLSRYQIRDL MWGGYLHDIG KVGIPDAVLL KKEQLTAKDW
     EVMKQHVLIG EKICQPLRSM RGVIPIIRHH HERWDGSGYP DALKGDDIPY LAQVFQLIDI
     YDALSSERPY KIAFTTEEAL SVMLEEANSG WRNPKLMQQF AEFIPYCQE
//