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Protein
Submitted name:

rRNA methyltransferase RsmB

Gene

sunL

Organism
Streptococcus pneumoniae (strain CGSP14)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.SAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei277S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei305S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei324S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei377NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotationImported, RNA-bindingPROSITE-ProRule annotationSAAS annotation, Transferase
Biological processrRNA processingSAAS annotation
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
rRNA methyltransferase RsmBImported
Gene namesi
Name:sunLImported
Ordered Locus Names:SPCG_1707Imported
OrganismiStreptococcus pneumoniae (strain CGSP14)Imported
Taxonomic identifieri516950 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000001682 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliB2IS84.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini159 – 436SAM_MT_RSMB_NOPInterPro annotationAdd BLAST278

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000037300.
KOiK03500.
OMAiLRVNRQH.

Family and domain databases

Gene3Di1.10.940.10. 1 hit.
3.40.50.150. 1 hit.
InterProiView protein in InterPro
IPR018314. Fmu/NOL1/Nop2p_CS.
IPR001678. MeTrfase_RsmB/NOP2.
IPR006027. NusB_RsmB_TIM44.
IPR023267. RCMT.
IPR004573. rRNA_ssu_MeTfrase_B.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF01189. Methyltr_RsmB-F. 1 hit.
PF01029. NusB. 1 hit.
PRINTSiPR02008. RCMTFAMILY.
SUPFAMiSSF48013. SSF48013. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00563. rsmB. 1 hit.
PROSITEiView protein in PROSITE
PS01153. NOL1_NOP2_SUN. 1 hit.
PS51686. SAM_MT_RSMB_NOP. 1 hit.

Sequencei

Sequence statusi: Complete.

B2IS84-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTKVETARS LALAVLEDVF VNQAYSNIAL NKHLKGSQLS AADKGLVTEL
60 70 80 90 100
VYGTVARKLT LEWYLSHFIE DRDQLDSWLY VLLLMSVYQL RYLDKIPDHA
110 120 130 140 150
VVNEAVELAK LRKKGSEKLV NAVLRRILRE GWPDIANIKR KNKRDSIAYS
160 170 180 190 200
LPVWLVTKLK EEYGEERAKA IFESLLVRNK ASIRVTDLSR KEEIQALLEA
210 220 230 240 250
NSSLLATTGL VKEQGHFAGH NLFADGAITI QDESSQLVAP TLDLQGDERV
260 270 280 290 300
LDACAAPGGK TAHIASYLTT GQVTALDLYD HKLDLIQENA QRLGVADRVQ
310 320 330 340 350
TQKLDARKVH EFFDQDSFDK ILVDAPCSGI GLLRRKPDIK YNKETADFAS
360 370 380 390 400
LQEIQLEILG SVCQILGKGG IITYSTCTIV SEENFQVVKA FLESHPEFEQ
410 420 430
VKLEHECKDI MKDGCILITP ELYGSDGFFI SQFRKISD
Length:438
Mass (Da):49,098
Last modified:June 10, 2008 - v1
Checksum:iE3E4FB62D586E37B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001033 Genomic DNA. Translation: ACB90959.1.

Genome annotation databases

EnsemblBacteriaiACB90959; ACB90959; SPCG_1707.
KEGGispw:SPCG_1707.
PATRICi19679738. VBIStrPne123335_1826.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001033 Genomic DNA. Translation: ACB90959.1.

3D structure databases

ProteinModelPortaliB2IS84.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACB90959; ACB90959; SPCG_1707.
KEGGispw:SPCG_1707.
PATRICi19679738. VBIStrPne123335_1826.

Phylogenomic databases

HOGENOMiHOG000037300.
KOiK03500.
OMAiLRVNRQH.

Family and domain databases

Gene3Di1.10.940.10. 1 hit.
3.40.50.150. 1 hit.
InterProiView protein in InterPro
IPR018314. Fmu/NOL1/Nop2p_CS.
IPR001678. MeTrfase_RsmB/NOP2.
IPR006027. NusB_RsmB_TIM44.
IPR023267. RCMT.
IPR004573. rRNA_ssu_MeTfrase_B.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF01189. Methyltr_RsmB-F. 1 hit.
PF01029. NusB. 1 hit.
PRINTSiPR02008. RCMTFAMILY.
SUPFAMiSSF48013. SSF48013. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00563. rsmB. 1 hit.
PROSITEiView protein in PROSITE
PS01153. NOL1_NOP2_SUN. 1 hit.
PS51686. SAM_MT_RSMB_NOP. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB2IS84_STRPS
AccessioniPrimary (citable) accession number: B2IS84
Entry historyiIntegrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: February 15, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.