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B2IRV3 (B2IRV3_STRPS) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length374 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site471Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2701Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1431Substrate By similarity HAMAP-Rule MF_01201
Binding site3171Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue471N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
B2IRV3 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: 71B255666051B88F

FASTA37440,908
        10         20         30         40         50         60 
MSFWRKIMKA SPHRPTKALI HLGAIRQNIQ QMGAHIPQGT LKWAVVKANA YGHGAVAVAK 

        70         80         90        100        110        120 
AIQDDVDGFC VSNIDEAIEL RQAGLSKPIL ILGVSEIEAV ALAKEYDFTL TVAGLEWIQA 

       130        140        150        160        170        180 
LLDKEVDLTG LTVHLKIDSG MGRIGFREVS EVEQAQDLLQ KHGVCVEGIF THFATADEES 

       190        200        210        220        230        240 
DDYFNAQLER FKTILASMKE VPELVHASNS ATTLWHVETI FNAVRMGDAM YGLNPSGAVL 

       250        260        270        280        290        300 
DLPYDLIPAL TLESALVHVK TVPAGACMGY GATYQADSEQ VIATVPIGYA DGWTRDMQNF 

       310        320        330        340        350        360 
SVLVDGQACP IVGRVSMDQI TIRLPKLYPL GTKVTLIGSN GDKEITATQV ATYRVTINYE 

       370 
VVCLLSDRIP REYY 

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References

[1]"Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14."
Ding F., Tang P., Hsu M.H., Cui P., Hu S., Yu J., Chiu C.H.
BMC Genomics 10:158-158(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CGSP14 EMBL ACB90922.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001033 Genomic DNA. Translation: ACB90922.1.
RefSeqYP_001836387.1. NC_010582.1.

3D structure databases

ProteinModelPortalB2IRV3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING516950.SPCG_1670.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACB90922; ACB90922; SPCG_1670.
GeneID6217624.
KEGGspw:SPCG_1670.
PATRIC19679658. VBIStrPne123335_1786.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMAITMDQLM.
OrthoDBEOG6PP9NJ.
ProtClustDBPRK00053.

Enzyme and pathway databases

BioCycSPNE516950:GI38-1683-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB2IRV3_STRPS
AccessionPrimary (citable) accession number: B2IRV3
Entry history
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: April 16, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)