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B2IRU8

- B2IRU8_STRPS

UniProt

B2IRU8 - B2IRU8_STRPS

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Protein
Submitted name:

Sialidase A (Neuraminidase A)

Gene
nanA, SPCG_1665
Organism
Streptococcus pneumoniae (strain CGSP14)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. exo-alpha-sialidase activity Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciSPNE516950:GI38-1678-MONOMER.

Protein family/group databases

CAZyiCBM40. Carbohydrate-Binding Module Family 40.
GH33. Glycoside Hydrolase Family 33.

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase A (Neuraminidase A)Imported
Gene namesi
Name:nanAImported
Ordered Locus Names:SPCG_1665Imported
OrganismiStreptococcus pneumoniae (strain CGSP14)Imported
Taxonomic identifieri516950 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000001682: Chromosome

Subcellular locationi

Secretedcell wall; Peptidoglycan-anchor By similarity SAAS annotations

GO - Cellular componenti

  1. cell wall Source: UniProtKB-SubCell
  2. extracellular region Source: UniProtKB-KW
  3. membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotations

Interactioni

Protein-protein interaction databases

STRINGi516950.SPCG_1665.

Structurei

3D structure databases

ProteinModelPortaliB2IRU8.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG4409.
HOGENOMiHOG000284737.
KOiK01186.
OMAiGGPKREN.
OrthoDBiEOG61CM2G.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProiIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR005877. YSIRK_signal_dom.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF02973. Sialidase. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view]
SMARTiSM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2IRU8-1 [UniParc]FASTAAdd to Basket

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MSYFRNRDID IERISMNRSV QERKCRYSIR KLSVGAVSMI VGAVVFGTSP    50
VLAQEGASEQ PLANETQLSG ESSTLTDTEK SQPSSETELS GNKQEQERKD 100
KQEEKIPRDY YARDLENVET VIEKEDVETN ASNGQRVDLS SELDKLKKLE 150
NATVHMEFKP DAKAPAFYNL FSVSSATKKD EYFTMAVYNN TATLEGRGSD 200
GQQFYGNYND APLKVKPGQW NSVTFTVEKP TAELPKGRVR LYVNGVLSRT 250
SLKSGNFIKD MPDVTHVQIG ATKRANNTVW GSNLQIQNLT VYNRALTPEE 300
VQKRSQLFKR SDLEKKLPEG AVLTEKTDIF ESGRNGKPNK DGIKSYRIPA 350
LLKTDKGTLI AGADERRLHS SDWGDIGMVI RRSEDNGKTW GDKVVISNLR 400
DNPEAKDPAA PSPLNIDMVL VQDPTTKRIF SIYDMFPEGR AVFGMPKTPE 450
KAYEKIGDKT YQILYKQGES GHYTVRENGE VYNAQNQKTD YRVVVNPTEP 500
GYRDKGNLYK GQELIGNIYF AHSTKNPFRV ANTSYLWMSY SDDDGKTWSA 550
PRDITPGLRK DWMKFLGTGP GTGIVLRNGP HKGRILIPVY TTNNVSHLNG 600
SQSSRVIYSD DHGKTWHAGE AVNDNRQVDG QKIHSSTMNN ERAQNTESTV 650
VQLNNGDVKL FMRGLTGDLQ VATSKDGGVT WEKDIKRYPQ VKDVYVQMSA 700
IHTMHEGKEY IILSNAGGPK RENGMVHLAR VEENGELTWL KHNPIQKGEF 750
AYNSLQELGN GEYGILYEHT EKGQNAYTLS FRKFNWDFLS KDLISPTEAK 800
VKRTREMGKG EMGKGVIGLE FDSEVLVNKA PTLQLANGKT ATFLTQYDSK 850
TLLFAVDKED IGQEIIGIAK GSIESMHNLP VNLAGARVPG GVNGSKAAVH 900
EVPEFTGGVN GTEPAVHEIA EYKGSDSLVT LTTKEDYTYK APLAQQALPE 950
TGNKESDLLA SLGLTAFFLG LFTLGKKREQ 980
Length:980
Mass (Da):109,129
Last modified:June 10, 2008 - v1
Checksum:i1EB4EDCC0FD82273
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001033 Genomic DNA. Translation: ACB90917.1.
RefSeqiWP_012386848.1. NC_010582.1.
YP_001836382.1. NC_010582.1.

Genome annotation databases

EnsemblBacteriaiACB90917; ACB90917; SPCG_1665.
GeneIDi6217600.
KEGGispw:SPCG_1665.
PATRICi19679644. VBIStrPne123335_1779.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001033 Genomic DNA. Translation: ACB90917.1 .
RefSeqi WP_012386848.1. NC_010582.1.
YP_001836382.1. NC_010582.1.

3D structure databases

ProteinModelPortali B2IRU8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 516950.SPCG_1665.

Protein family/group databases

CAZyi CBM40. Carbohydrate-Binding Module Family 40.
GH33. Glycoside Hydrolase Family 33.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACB90917 ; ACB90917 ; SPCG_1665 .
GeneIDi 6217600.
KEGGi spw:SPCG_1665.
PATRICi 19679644. VBIStrPne123335_1779.

Phylogenomic databases

eggNOGi COG4409.
HOGENOMi HOG000284737.
KOi K01186.
OMAi GGPKREN.
OrthoDBi EOG61CM2G.

Enzyme and pathway databases

BioCyci SPNE516950:GI38-1678-MONOMER.

Family and domain databases

Gene3Di 2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProi IPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR005877. YSIRK_signal_dom.
[Graphical view ]
PANTHERi PTHR10628. PTHR10628. 1 hit.
Pfami PF02973. Sialidase. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view ]
SMARTi SM00282. LamG. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
TIGRFAMsi TIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEi PS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14."
    Ding F., Tang P., Hsu M.H., Cui P., Hu S., Yu J., Chiu C.H.
    BMC Genomics 10:158-158(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CGSP14Imported.

Entry informationi

Entry nameiB2IRU8_STRPS
AccessioniPrimary (citable) accession number: B2IRU8
Entry historyi
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: September 3, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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