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B2IRU8

- B2IRU8_STRPS

UniProt

B2IRU8 - B2IRU8_STRPS

Protein
Submitted name:

Sialidase A (Neuraminidase A)

Gene

nanA

Organism
Streptococcus pneumoniae (strain CGSP14)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (10 Jun 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. exo-alpha-sialidase activity Source: InterPro

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro

    Enzyme and pathway databases

    BioCyciSPNE516950:GI38-1678-MONOMER.

    Protein family/group databases

    CAZyiCBM40. Carbohydrate-Binding Module Family 40.
    GH33. Glycoside Hydrolase Family 33.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Sialidase A (Neuraminidase A)Imported
    Gene namesi
    Name:nanAImported
    Ordered Locus Names:SPCG_1665Imported
    OrganismiStreptococcus pneumoniae (strain CGSP14)Imported
    Taxonomic identifieri516950 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000001682: Chromosome

    Subcellular locationi

    Secretedcell wall SAAS annotation; Peptidoglycan-anchor SAAS annotation

    GO - Cellular componenti

    1. cell wall Source: UniProtKB-SubCell
    2. extracellular region Source: UniProtKB-KW
    3. membrane Source: InterPro

    Keywords - Cellular componenti

    SecretedSAAS annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi516950.SPCG_1665.

    Structurei

    3D structure databases

    ProteinModelPortaliB2IRU8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG4409.
    HOGENOMiHOG000284737.
    KOiK01186.
    OMAiGGPKREN.
    OrthoDBiEOG61CM2G.

    Family and domain databases

    Gene3Di2.120.10.10. 2 hits.
    2.60.120.200. 1 hit.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR004124. Glyco_hydro_33_N.
    IPR001791. Laminin_G.
    IPR019931. LPXTG_anchor.
    IPR026856. Sialidase_fam.
    IPR011040. Sialidases.
    IPR005877. YSIRK_signal_dom.
    [Graphical view]
    PANTHERiPTHR10628. PTHR10628. 1 hit.
    PfamiPF02973. Sialidase. 1 hit.
    PF04650. YSIRK_signal. 1 hit.
    [Graphical view]
    SMARTiSM00282. LamG. 1 hit.
    [Graphical view]
    SUPFAMiSSF49899. SSF49899. 1 hit.
    SSF50939. SSF50939. 2 hits.
    TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
    TIGR01168. YSIRK_signal. 1 hit.
    PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B2IRU8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSYFRNRDID IERISMNRSV QERKCRYSIR KLSVGAVSMI VGAVVFGTSP    50
    VLAQEGASEQ PLANETQLSG ESSTLTDTEK SQPSSETELS GNKQEQERKD 100
    KQEEKIPRDY YARDLENVET VIEKEDVETN ASNGQRVDLS SELDKLKKLE 150
    NATVHMEFKP DAKAPAFYNL FSVSSATKKD EYFTMAVYNN TATLEGRGSD 200
    GQQFYGNYND APLKVKPGQW NSVTFTVEKP TAELPKGRVR LYVNGVLSRT 250
    SLKSGNFIKD MPDVTHVQIG ATKRANNTVW GSNLQIQNLT VYNRALTPEE 300
    VQKRSQLFKR SDLEKKLPEG AVLTEKTDIF ESGRNGKPNK DGIKSYRIPA 350
    LLKTDKGTLI AGADERRLHS SDWGDIGMVI RRSEDNGKTW GDKVVISNLR 400
    DNPEAKDPAA PSPLNIDMVL VQDPTTKRIF SIYDMFPEGR AVFGMPKTPE 450
    KAYEKIGDKT YQILYKQGES GHYTVRENGE VYNAQNQKTD YRVVVNPTEP 500
    GYRDKGNLYK GQELIGNIYF AHSTKNPFRV ANTSYLWMSY SDDDGKTWSA 550
    PRDITPGLRK DWMKFLGTGP GTGIVLRNGP HKGRILIPVY TTNNVSHLNG 600
    SQSSRVIYSD DHGKTWHAGE AVNDNRQVDG QKIHSSTMNN ERAQNTESTV 650
    VQLNNGDVKL FMRGLTGDLQ VATSKDGGVT WEKDIKRYPQ VKDVYVQMSA 700
    IHTMHEGKEY IILSNAGGPK RENGMVHLAR VEENGELTWL KHNPIQKGEF 750
    AYNSLQELGN GEYGILYEHT EKGQNAYTLS FRKFNWDFLS KDLISPTEAK 800
    VKRTREMGKG EMGKGVIGLE FDSEVLVNKA PTLQLANGKT ATFLTQYDSK 850
    TLLFAVDKED IGQEIIGIAK GSIESMHNLP VNLAGARVPG GVNGSKAAVH 900
    EVPEFTGGVN GTEPAVHEIA EYKGSDSLVT LTTKEDYTYK APLAQQALPE 950
    TGNKESDLLA SLGLTAFFLG LFTLGKKREQ 980
    Length:980
    Mass (Da):109,129
    Last modified:June 10, 2008 - v1
    Checksum:i1EB4EDCC0FD82273
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001033 Genomic DNA. Translation: ACB90917.1.
    RefSeqiWP_012386848.1. NC_010582.1.
    YP_001836382.1. NC_010582.1.

    Genome annotation databases

    EnsemblBacteriaiACB90917; ACB90917; SPCG_1665.
    GeneIDi6217600.
    KEGGispw:SPCG_1665.
    PATRICi19679644. VBIStrPne123335_1779.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001033 Genomic DNA. Translation: ACB90917.1 .
    RefSeqi WP_012386848.1. NC_010582.1.
    YP_001836382.1. NC_010582.1.

    3D structure databases

    ProteinModelPortali B2IRU8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 516950.SPCG_1665.

    Protein family/group databases

    CAZyi CBM40. Carbohydrate-Binding Module Family 40.
    GH33. Glycoside Hydrolase Family 33.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACB90917 ; ACB90917 ; SPCG_1665 .
    GeneIDi 6217600.
    KEGGi spw:SPCG_1665.
    PATRICi 19679644. VBIStrPne123335_1779.

    Phylogenomic databases

    eggNOGi COG4409.
    HOGENOMi HOG000284737.
    KOi K01186.
    OMAi GGPKREN.
    OrthoDBi EOG61CM2G.

    Enzyme and pathway databases

    BioCyci SPNE516950:GI38-1678-MONOMER.

    Family and domain databases

    Gene3Di 2.120.10.10. 2 hits.
    2.60.120.200. 1 hit.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR004124. Glyco_hydro_33_N.
    IPR001791. Laminin_G.
    IPR019931. LPXTG_anchor.
    IPR026856. Sialidase_fam.
    IPR011040. Sialidases.
    IPR005877. YSIRK_signal_dom.
    [Graphical view ]
    PANTHERi PTHR10628. PTHR10628. 1 hit.
    Pfami PF02973. Sialidase. 1 hit.
    PF04650. YSIRK_signal. 1 hit.
    [Graphical view ]
    SMARTi SM00282. LamG. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49899. SSF49899. 1 hit.
    SSF50939. SSF50939. 2 hits.
    TIGRFAMsi TIGR01167. LPXTG_anchor. 1 hit.
    TIGR01168. YSIRK_signal. 1 hit.
    PROSITEi PS50847. GRAM_POS_ANCHORING. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14."
      Ding F., Tang P., Hsu M.-H., Cui P., Hu S., Yu J., Chiu C.-H.
      BMC Genomics 10:158-158(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CGSP14Imported.

    Entry informationi

    Entry nameiB2IRU8_STRPS
    AccessioniPrimary (citable) accession number: B2IRU8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 10, 2008
    Last sequence update: June 10, 2008
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3