B2IRU8 (B2IRU8_STRPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Sialidase A (Neuraminidase A) EMBL ACB90917.1

Gene names

Name:	nanA EMBL ACB90917.1
Ordered Locus Names:	SPCG_1665

Organism

Streptococcus pneumoniae (strain CGSP14) [Complete proteome] [HAMAP] EMBL ACB90917.1

Taxonomic identifier

516950 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus › Streptococcus pneumoniae

Protein attributes

Sequence length	980 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Cellular component	Secreted SAAS SAAS005877
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-KW membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	exo-alpha-sialidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2IRU8 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: 1EB4EDCC0FD82273	FASTA	980	109,129
	10 20 30 40 50 60 MSYFRNRDID IERISMNRSV QERKCRYSIR KLSVGAVSMI VGAVVFGTSP VLAQEGASEQ 70 80 90 100 110 120 PLANETQLSG ESSTLTDTEK SQPSSETELS GNKQEQERKD KQEEKIPRDY YARDLENVET 130 140 150 160 170 180 VIEKEDVETN ASNGQRVDLS SELDKLKKLE NATVHMEFKP DAKAPAFYNL FSVSSATKKD 190 200 210 220 230 240 EYFTMAVYNN TATLEGRGSD GQQFYGNYND APLKVKPGQW NSVTFTVEKP TAELPKGRVR 250 260 270 280 290 300 LYVNGVLSRT SLKSGNFIKD MPDVTHVQIG ATKRANNTVW GSNLQIQNLT VYNRALTPEE 310 320 330 340 350 360 VQKRSQLFKR SDLEKKLPEG AVLTEKTDIF ESGRNGKPNK DGIKSYRIPA LLKTDKGTLI 370 380 390 400 410 420 AGADERRLHS SDWGDIGMVI RRSEDNGKTW GDKVVISNLR DNPEAKDPAA PSPLNIDMVL 430 440 450 460 470 480 VQDPTTKRIF SIYDMFPEGR AVFGMPKTPE KAYEKIGDKT YQILYKQGES GHYTVRENGE 490 500 510 520 530 540 VYNAQNQKTD YRVVVNPTEP GYRDKGNLYK GQELIGNIYF AHSTKNPFRV ANTSYLWMSY 550 560 570 580 590 600 SDDDGKTWSA PRDITPGLRK DWMKFLGTGP GTGIVLRNGP HKGRILIPVY TTNNVSHLNG 610 620 630 640 650 660 SQSSRVIYSD DHGKTWHAGE AVNDNRQVDG QKIHSSTMNN ERAQNTESTV VQLNNGDVKL 670 680 690 700 710 720 FMRGLTGDLQ VATSKDGGVT WEKDIKRYPQ VKDVYVQMSA IHTMHEGKEY IILSNAGGPK 730 740 750 760 770 780 RENGMVHLAR VEENGELTWL KHNPIQKGEF AYNSLQELGN GEYGILYEHT EKGQNAYTLS 790 800 810 820 830 840 FRKFNWDFLS KDLISPTEAK VKRTREMGKG EMGKGVIGLE FDSEVLVNKA PTLQLANGKT 850 860 870 880 890 900 ATFLTQYDSK TLLFAVDKED IGQEIIGIAK GSIESMHNLP VNLAGARVPG GVNGSKAAVH 910 920 930 940 950 960 EVPEFTGGVN GTEPAVHEIA EYKGSDSLVT LTTKEDYTYK APLAQQALPE TGNKESDLLA 970 980 SLGLTAFFLG LFTLGKKREQ

References

[1]

"Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14." Ding F., Tang P., Hsu M.-H., Cui P., Hu S., Yu J., Chiu C.-H. BMC Genomics 10:158-158(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CGSP14.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001033 Genomic DNA. Translation: ACB90917.1.
RefSeq	YP_001836382.1. NC_010582.1.
3D structure databases
ProteinModelPortal	B2IRU8.
ModBase	Search...
Protein-protein interaction databases
STRING	516950.SPCG_1665.
Protein family/group databases
CAZy	CBM40. Carbohydrate-Binding Module Family 40. GH33. Glycoside Hydrolase Family 33.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACB90917; ACB90917; SPCG_1665.
GeneID	6217600.
KEGG	spw:SPCG_1665.
PATRIC	19679644. VBIStrPne123335_1779.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG4409.
HOGENOM	HOG000284737.
KO	K01186.
OMA	PLANETQ.
ProtClustDB	CLSK560471.
Family and domain databases
Gene3D	2.120.10.10. 2 hits. 2.60.120.200. 1 hit.
InterPro	IPR008985. ConA-like_lec_gl_sf. IPR013320. ConA-like_subgrp. IPR004124. Glyco_hydro_33_N. IPR005877. Gpos_YSIRK. IPR001791. Laminin_G. IPR019931. LPXTG-motif_cell_wall_anchor. IPR026856. Sialidase_fam. IPR011040. Sialidases. [Graphical view]
PANTHER	PTHR10628. PTHR10628. 1 hit.
Pfam	PF02973. Sialidase. 1 hit. PF04650. YSIRK_signal. 1 hit. [Graphical view]
SMART	SM00282. LamG. 1 hit. [Graphical view]
SUPFAM	SSF49899. ConA_like_lec_gl. 1 hit. SSF50939. Sialidase. 1 hit.
TIGRFAMs	TIGR01167. LPXTG_anchor. 1 hit. TIGR01168. YSIRK_signal. 1 hit.
PROSITE	PS50847. GRAM_POS_ANCHORING. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2IRU8_STRPS

Accession

Primary (citable) accession number: B2IRU8

Entry history

Integrated into UniProtKB/TrEMBL:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	May 1, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)