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Protein
Submitted name:

Neuraminidase B

Gene

nanB

Organism
Streptococcus pneumoniae (strain CGSP14)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-sialidase activity Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciSPNE516950:GI38-1673-MONOMER.

Protein family/group databases

CAZyiCBM40. Carbohydrate-Binding Module Family 40.
GH33. Glycoside Hydrolase Family 33.

Names & Taxonomyi

Protein namesi
Submitted name:
Neuraminidase BImported
Gene namesi
Name:nanBImported
Ordered Locus Names:SPCG_1660Imported
OrganismiStreptococcus pneumoniae (strain CGSP14)Imported
Taxonomic identifieri516950 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000001682: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi516950.SPCG_1660.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG4409.
HOGENOMiHOG000285031.
KOiK01186.
OMAiWRYHYDI.
OrthoDBiEOG61CM2G.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.40.220.10. 1 hit.
2.60.120.200. 1 hit.
InterProiIPR002860. BNR_rpt.
IPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR011040. Sialidases.
IPR023364. Trans_sialidase_dom3.
[Graphical view]
PfamiPF02012. BNR. 1 hit.
PF02973. Sialidase. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.

Sequencei

Sequence statusi: Complete.

B2IRU3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKRGLYSKL GISVVGISLL MGVPTLIHAN ELNYGQLSIS PIFQGGSYQL
60 70 80 90 100
NNKSIDISSL LLDKLSGESQ TVVMKFKADK PNSLQALFGL SNSKAGFKNN
110 120 130 140 150
YFSIFMRDSG EIGVEIRDAQ KGINYLFSRP ASLWGKHKGQ AVENTLVFVS
160 170 180 190 200
DSKDKTYTMY VNGIEVFSET VDTFLPISNI NGIDKATLGA VNREGKEHYL
210 220 230 240 250
AKGSIDEISL FNKAISDQEV SNIPLSNPFQ LIFQSGDSTQ ANYFRIPTLY
260 270 280 290 300
TLSSGRVLSS IDARYGGTHD SKSKINIATS YSDDNGKTWS EPIFAMKFND
310 320 330 340 350
YEEQLVYWPR DNKLKNSQIS GSASFIDSSI VEDKKSGKTI LLADVMPAGI
360 370 380 390 400
GNNNANKADS GFKEINGHYY LKLKKNGDND FRYTVRENGV VYDETTNKPT
410 420 430 440 450
NYTINDKYEV LEGGKSLTVE QYSVDFDSGS LREKHNGKQV PMNVFYKDSL
460 470 480 490 500
FKVTPTNYIA MTTSQNRGES WEQFKLLPPF LGEKHNGTYL CPGQGLALKS
510 520 530 540 550
SNRLIFATYT SGELTYLISD DSGQTWKKSS ASIPFKNATA EAQMVELRDG
560 570 580 590 600
VIRTFFRTTT GKIAYMTSRD SGETWSEVSY IDGIQQTSYG TQVSAIKYSQ
610 620 630 640 650
LIDGKEAVIL STPNSRSGRK GGQLVVGLVN KEDDSIDWKY HYDIDLPSYG
660 670 680 690
YAYSAITELP NHHIGVLFEK YDSWSRNELH LSNVVQYIDL EINDLTK
Length:697
Mass (Da):77,682
Last modified:June 10, 2008 - v1
Checksum:i28C580B60BE117B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001033 Genomic DNA. Translation: ACB90912.1.
RefSeqiWP_001042170.1. NC_010582.1.
YP_001836377.1. NC_010582.1.

Genome annotation databases

EnsemblBacteriaiACB90912; ACB90912; SPCG_1660.
GeneIDi6217694.
KEGGispw:SPCG_1660.
PATRICi19679632. VBIStrPne123335_1773.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001033 Genomic DNA. Translation: ACB90912.1.
RefSeqiWP_001042170.1. NC_010582.1.
YP_001836377.1. NC_010582.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi516950.SPCG_1660.

Protein family/group databases

CAZyiCBM40. Carbohydrate-Binding Module Family 40.
GH33. Glycoside Hydrolase Family 33.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACB90912; ACB90912; SPCG_1660.
GeneIDi6217694.
KEGGispw:SPCG_1660.
PATRICi19679632. VBIStrPne123335_1773.

Phylogenomic databases

eggNOGiCOG4409.
HOGENOMiHOG000285031.
KOiK01186.
OMAiWRYHYDI.
OrthoDBiEOG61CM2G.

Enzyme and pathway databases

BioCyciSPNE516950:GI38-1673-MONOMER.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.40.220.10. 1 hit.
2.60.120.200. 1 hit.
InterProiIPR002860. BNR_rpt.
IPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR011040. Sialidases.
IPR023364. Trans_sialidase_dom3.
[Graphical view]
PfamiPF02012. BNR. 1 hit.
PF02973. Sialidase. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. "Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14."
    Ding F., Tang P., Hsu M.-H., Cui P., Hu S., Yu J., Chiu C.-H.
    BMC Genomics 10:158-158(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CGSP14Imported.

Entry informationi

Entry nameiB2IRU3_STRPS
AccessioniPrimary (citable) accession number: B2IRU3
Entry historyi
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: February 4, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.