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B2IRE8

- B2IRE8_STRPS

UniProt

B2IRE8 - B2IRE8_STRPS

Protein

Aldose 1-epimerase

Gene

galM

Organism
Streptococcus pneumoniae (strain CGSP14)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (10 Jun 2008)
      Previous versions | rss
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    Functioni

    Converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose.UniRule annotation

    Catalytic activityi

    Alpha-D-glucose = beta-D-glucose.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. aldose 1-epimerase activity Source: UniProtKB-EC
    2. carbohydrate binding Source: InterPro

    GO - Biological processi

    1. hexose metabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotation

    Keywords - Biological processi

    Carbohydrate metabolismUniRule annotation

    Enzyme and pathway databases

    BioCyciSPNE516950:GI38-73-MONOMER.
    UniPathwayiUPA00242.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
    Alternative name(s):
    Galactose mutarotaseUniRule annotation
    Gene namesi
    Name:galMImported
    Ordered Locus Names:SPCG_0067Imported
    OrganismiStreptococcus pneumoniae (strain CGSP14)Imported
    Taxonomic identifieri516950 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000001682: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi516950.SPCG_0067.

    Structurei

    3D structure databases

    ProteinModelPortaliB2IRE8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the aldose epimerase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2017.
    HOGENOMiHOG000072798.
    KOiK01785.
    OMAiAVNIAHF.
    OrthoDBiEOG69WFM5.

    Family and domain databases

    Gene3Di2.70.98.10. 1 hit.
    InterProiIPR018052. Ald1_epimerase_CS.
    IPR015443. Aldose_1-epimerase.
    IPR008183. Aldose_1/G6P_1-epimerase.
    IPR011013. Gal_mutarotase_SF_dom.
    IPR014718. Glyco_hydro-type_carb-bd_sub.
    [Graphical view]
    PfamiPF01263. Aldose_epim. 1 hit.
    [Graphical view]
    PIRSFiPIRSF005096. GALM. 1 hit.
    SUPFAMiSSF74650. SSF74650. 1 hit.
    PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B2IRE8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKAYTERVFG NVEGEDVLAY RFETDGGYQL EVMTYGATIL RYVAPDKAGN    50
    FANVILGFDD FDSYVGNSPK HGASVGPVAG RIAGATFELN GKTYDLEVNN 100
    ASNCNHSGST GWDSSLFEVE EVSDHGLTLY TERTDGTGGF PGNLKIWISY 150
    HLEETGAYEI SYKVTTDQDT LVNPTNHSYF NLSGDFTQTI DRHVFQLNTE 200
    GIYSIAPDGV PAKTPEANRD VVKHIYNGAL LKDIFAEEDE QIQLASGLDH 250
    PFALPAGHDN AGFLYDQNSG RFLLFKTEAP CFVVYTANFV DESVIIGGQP 300
    MLQHNGIALE AQALPDAIHS DLKGQVILKA GQTFTSKTRY ELVVK 345
    Length:345
    Mass (Da):37,766
    Last modified:June 10, 2008 - v1
    Checksum:i4C4D93A872C9F2BA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001033 Genomic DNA. Translation: ACB89319.1.
    RefSeqiYP_001834784.1. NC_010582.1.

    Genome annotation databases

    EnsemblBacteriaiACB89319; ACB89319; SPCG_0067.
    GeneIDi6218128.
    KEGGispw:SPCG_0067.
    PATRICi19676231. VBIStrPne123335_0074.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001033 Genomic DNA. Translation: ACB89319.1 .
    RefSeqi YP_001834784.1. NC_010582.1.

    3D structure databases

    ProteinModelPortali B2IRE8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 516950.SPCG_0067.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACB89319 ; ACB89319 ; SPCG_0067 .
    GeneIDi 6218128.
    KEGGi spw:SPCG_0067.
    PATRICi 19676231. VBIStrPne123335_0074.

    Phylogenomic databases

    eggNOGi COG2017.
    HOGENOMi HOG000072798.
    KOi K01785.
    OMAi AVNIAHF.
    OrthoDBi EOG69WFM5.

    Enzyme and pathway databases

    UniPathwayi UPA00242 .
    BioCyci SPNE516950:GI38-73-MONOMER.

    Family and domain databases

    Gene3Di 2.70.98.10. 1 hit.
    InterProi IPR018052. Ald1_epimerase_CS.
    IPR015443. Aldose_1-epimerase.
    IPR008183. Aldose_1/G6P_1-epimerase.
    IPR011013. Gal_mutarotase_SF_dom.
    IPR014718. Glyco_hydro-type_carb-bd_sub.
    [Graphical view ]
    Pfami PF01263. Aldose_epim. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF005096. GALM. 1 hit.
    SUPFAMi SSF74650. SSF74650. 1 hit.
    PROSITEi PS00545. ALDOSE_1_EPIMERASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14."
      Ding F., Tang P., Hsu M.-H., Cui P., Hu S., Yu J., Chiu C.-H.
      BMC Genomics 10:158-158(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CGSP14Imported.

    Entry informationi

    Entry nameiB2IRE8_STRPS
    AccessioniPrimary (citable) accession number: B2IRE8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 10, 2008
    Last sequence update: June 10, 2008
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3