B2IRE8 (B2IRE8_STRPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aldose 1-epimerase PIRNR PIRNR005096
EC=5.1.3.3 PIRNR PIRNR005096

Alternative name(s):
Galactose mutarotase PIRNR PIRNR005096

Gene names

Name:	galM EMBL ACB89319.1
Ordered Locus Names:	SPCG_0067

Organism

Streptococcus pneumoniae (strain CGSP14) [Complete proteome] [HAMAP] EMBL ACB89319.1

Taxonomic identifier

516950 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus › Streptococcus pneumoniae

Protein attributes

Sequence length	345 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose By similarity. PIRNR PIRNR005096
Catalytic activity	Alpha-D-glucose = beta-D-glucose. PIRNR PIRNR005096
Pathway	Carbohydrate metabolism; hexose metabolism. PIRNR PIRNR005096
Sequence similarities	Belongs to the aldose epimerase family. PIRNR PIRNR005096

Ontologies

Keywords
Biological process	Carbohydrate metabolism PIRNR PIRNR005096
Molecular function	Isomerase PIRNR PIRNR005096
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	hexose metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	carbohydrate binding Inferred from electronic annotation. Source: InterPro isomerase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2IRE8 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: 4C4D93A872C9F2BA	FASTA	345	37,766
	10 20 30 40 50 60 MKAYTERVFG NVEGEDVLAY RFETDGGYQL EVMTYGATIL RYVAPDKAGN FANVILGFDD 70 80 90 100 110 120 FDSYVGNSPK HGASVGPVAG RIAGATFELN GKTYDLEVNN ASNCNHSGST GWDSSLFEVE 130 140 150 160 170 180 EVSDHGLTLY TERTDGTGGF PGNLKIWISY HLEETGAYEI SYKVTTDQDT LVNPTNHSYF 190 200 210 220 230 240 NLSGDFTQTI DRHVFQLNTE GIYSIAPDGV PAKTPEANRD VVKHIYNGAL LKDIFAEEDE 250 260 270 280 290 300 QIQLASGLDH PFALPAGHDN AGFLYDQNSG RFLLFKTEAP CFVVYTANFV DESVIIGGQP 310 320 330 340 MLQHNGIALE AQALPDAIHS DLKGQVILKA GQTFTSKTRY ELVVK

References

[1]

"Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14." Ding F., Tang P., Hsu M.-H., Cui P., Hu S., Yu J., Chiu C.-H. BMC Genomics 10:158-158(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CGSP14.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001033 Genomic DNA. Translation: ACB89319.1.
RefSeq	YP_001834784.1. NC_010582.1.
3D structure databases
ProteinModelPortal	B2IRE8.
ModBase	Search...
Protein-protein interaction databases
STRING	516950.SPCG_0067.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACB89319; ACB89319; SPCG_0067.
GeneID	6218128.
KEGG	spw:SPCG_0067.
PATRIC	19676231. VBIStrPne123335_0074.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2017.
HOGENOM	HOG000072798.
KO	K01785.
OMA	YPGNLKL.
ProtClustDB	CLSK883903.
Enzyme and pathway databases
UniPathway	UPA00242.
Family and domain databases
Gene3D	2.70.98.10. 1 hit.
InterPro	IPR018052. Ald1_epimerase_CS. IPR015443. Aldose_1-epimerase. IPR008183. Aldose_1/G6P_1-epimerase. IPR011013. Gal_mutarotase_SF_dom. IPR014718. Glyco_hydro-type_carb-bd_sub. [Graphical view]
PANTHER	PTHR10091. PTHR10091. 1 hit.
Pfam	PF01263. Aldose_epim. 1 hit. [Graphical view]
PIRSF	PIRSF005096. GALM. 1 hit.
SUPFAM	SSF74650. Gal_mut_like. 1 hit.
PROSITE	PS00545. ALDOSE_1_EPIMERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2IRE8_STRPS

Accession

Primary (citable) accession number: B2IRE8

Entry history

Integrated into UniProtKB/TrEMBL:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	May 1, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)