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B2IRE8

- B2IRE8_STRPS

UniProt

B2IRE8 - B2IRE8_STRPS

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Protein

Aldose 1-epimerase

Gene
galM, SPCG_0067
Organism
Streptococcus pneumoniae (strain CGSP14)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose By similarity.UniRule annotation

Catalytic activityi

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. aldose 1-epimerase activity Source: UniProtKB-EC
  2. carbohydrate binding Source: InterPro

GO - Biological processi

  1. hexose metabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

BioCyciSPNE516950:GI38-73-MONOMER.
UniPathwayiUPA00242.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
Alternative name(s):
Galactose mutarotase
Gene namesi
Name:galMImported
Ordered Locus Names:SPCG_0067Imported
OrganismiStreptococcus pneumoniae (strain CGSP14)Imported
Taxonomic identifieri516950 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000001682: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi516950.SPCG_0067.

Structurei

3D structure databases

ProteinModelPortaliB2IRE8.

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2017.
HOGENOMiHOG000072798.
KOiK01785.
OMAiAVNIAHF.
OrthoDBiEOG69WFM5.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2IRE8-1 [UniParc]FASTAAdd to Basket

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MKAYTERVFG NVEGEDVLAY RFETDGGYQL EVMTYGATIL RYVAPDKAGN    50
FANVILGFDD FDSYVGNSPK HGASVGPVAG RIAGATFELN GKTYDLEVNN 100
ASNCNHSGST GWDSSLFEVE EVSDHGLTLY TERTDGTGGF PGNLKIWISY 150
HLEETGAYEI SYKVTTDQDT LVNPTNHSYF NLSGDFTQTI DRHVFQLNTE 200
GIYSIAPDGV PAKTPEANRD VVKHIYNGAL LKDIFAEEDE QIQLASGLDH 250
PFALPAGHDN AGFLYDQNSG RFLLFKTEAP CFVVYTANFV DESVIIGGQP 300
MLQHNGIALE AQALPDAIHS DLKGQVILKA GQTFTSKTRY ELVVK 345
Length:345
Mass (Da):37,766
Last modified:June 10, 2008 - v1
Checksum:i4C4D93A872C9F2BA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001033 Genomic DNA. Translation: ACB89319.1.
RefSeqiYP_001834784.1. NC_010582.1.

Genome annotation databases

EnsemblBacteriaiACB89319; ACB89319; SPCG_0067.
GeneIDi6218128.
KEGGispw:SPCG_0067.
PATRICi19676231. VBIStrPne123335_0074.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001033 Genomic DNA. Translation: ACB89319.1 .
RefSeqi YP_001834784.1. NC_010582.1.

3D structure databases

ProteinModelPortali B2IRE8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 516950.SPCG_0067.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACB89319 ; ACB89319 ; SPCG_0067 .
GeneIDi 6218128.
KEGGi spw:SPCG_0067.
PATRICi 19676231. VBIStrPne123335_0074.

Phylogenomic databases

eggNOGi COG2017.
HOGENOMi HOG000072798.
KOi K01785.
OMAi AVNIAHF.
OrthoDBi EOG69WFM5.

Enzyme and pathway databases

UniPathwayi UPA00242 .
BioCyci SPNE516950:GI38-73-MONOMER.

Family and domain databases

Gene3Di 2.70.98.10. 1 hit.
InterProi IPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view ]
Pfami PF01263. Aldose_epim. 1 hit.
[Graphical view ]
PIRSFi PIRSF005096. GALM. 1 hit.
SUPFAMi SSF74650. SSF74650. 1 hit.
PROSITEi PS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14."
    Ding F., Tang P., Hsu M.H., Cui P., Hu S., Yu J., Chiu C.H.
    BMC Genomics 10:158-158(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CGSP14Imported.

Entry informationi

Entry nameiB2IRE8_STRPS
AccessioniPrimary (citable) accession number: B2IRE8
Entry historyi
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: June 11, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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