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B2IR82

- WHIA_STRPS

UniProt

B2IR82 - WHIA_STRPS

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Protein
Putative sporulation transcription regulator WhiA
Gene
whiA, SPCG_1549
Organism
Streptococcus pneumoniae (strain CGSP14)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

May be required for sporulation By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi272 – 30332H-T-H motif Reviewed prediction
Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. endonuclease activity Source: InterPro

GO - Biological processi

  1. regulation of sporulation Source: UniProtKB-HAMAP
  2. regulation of transcription, DNA-templated Source: UniProtKB-KW
  3. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciSPNE516950:GI38-1561-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative sporulation transcription regulator WhiA
Gene namesi
Name:whiA
Ordered Locus Names:SPCG_1549
OrganismiStreptococcus pneumoniae (strain CGSP14)
Taxonomic identifieri516950 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000001682: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 303303Putative sporulation transcription regulator WhiAUniRule annotation
PRO_0000376579Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi516950.SPCG_1549.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1481.
HOGENOMiHOG000040187.
KOiK09762.
OMAiHKFMLDA.
OrthoDBiEOG68WR87.

Family and domain databases

Gene3Di3.10.28.10. 1 hit.
HAMAPiMF_01420. HTH_type_WhiA.
InterProiIPR027434. Homing_endonucl.
IPR018478. Sporu_reg_WhiA_N_dom.
IPR003802. Sporulation_regulator_WhiA.
IPR023054. Sporulation_regulator_WhiA_C.
[Graphical view]
PfamiPF02650. HTH_WhiA. 1 hit.
PF10298. WhiA_N. 1 hit.
[Graphical view]
SUPFAMiSSF55608. SSF55608. 1 hit.
TIGRFAMsiTIGR00647. MG103. 1 hit.

Sequencei

Sequence statusi: Complete.

B2IR82-1 [UniParc]FASTAAdd to Basket

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MSFTVAVKEE ILGQHHLSRH ELSAIIKMSG SIGLSTSGLT LSVVTENAKL    50
ARHLYESFLH FYEIKSEIRH HQRSNLRKNR VYTVFTDEKV QDLLSDLHLA 100
DSFFGLETGI DEAILSDEEA GRAYLCGAFL ANGSIRDPES GKYQLEISSV 150
YLDHAQGIAS LLQQFLLDAK VLERKKGAVT YLQRAEDIMD FLIVIGAMQA 200
RDDFERVKIL RETRNDLNRA NNAETANIAR TVSASMKTIN NISKIKDIMG 250
LENLPVDLQE VAQLRIQHPD YSIQQLADSL STPLTKSGVN HRLRKINKIA 300
DEL 303
Length:303
Mass (Da):34,062
Last modified:June 10, 2008 - v1
Checksum:iAC20DED7D3138041
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001033 Genomic DNA. Translation: ACB90801.1.
RefSeqiYP_001836266.1. NC_010582.1.

Genome annotation databases

EnsemblBacteriaiACB90801; ACB90801; SPCG_1549.
GeneIDi6217597.
KEGGispw:SPCG_1549.
PATRICi19679400. VBIStrPne123335_1657.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001033 Genomic DNA. Translation: ACB90801.1 .
RefSeqi YP_001836266.1. NC_010582.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 516950.SPCG_1549.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACB90801 ; ACB90801 ; SPCG_1549 .
GeneIDi 6217597.
KEGGi spw:SPCG_1549.
PATRICi 19679400. VBIStrPne123335_1657.

Phylogenomic databases

eggNOGi COG1481.
HOGENOMi HOG000040187.
KOi K09762.
OMAi HKFMLDA.
OrthoDBi EOG68WR87.

Enzyme and pathway databases

BioCyci SPNE516950:GI38-1561-MONOMER.

Family and domain databases

Gene3Di 3.10.28.10. 1 hit.
HAMAPi MF_01420. HTH_type_WhiA.
InterProi IPR027434. Homing_endonucl.
IPR018478. Sporu_reg_WhiA_N_dom.
IPR003802. Sporulation_regulator_WhiA.
IPR023054. Sporulation_regulator_WhiA_C.
[Graphical view ]
Pfami PF02650. HTH_WhiA. 1 hit.
PF10298. WhiA_N. 1 hit.
[Graphical view ]
SUPFAMi SSF55608. SSF55608. 1 hit.
TIGRFAMsi TIGR00647. MG103. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14."
    Ding F., Tang P., Hsu M.-H., Cui P., Hu S., Yu J., Chiu C.-H.
    BMC Genomics 10:158-158(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CGSP14.

Entry informationi

Entry nameiWHIA_STRPS
AccessioniPrimary (citable) accession number: B2IR82
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 26, 2009
Last sequence update: June 10, 2008
Last modified: September 3, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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