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B2IR82

- WHIA_STRPS

UniProt

B2IR82 - WHIA_STRPS

Protein

Putative sporulation transcription regulator WhiA

Gene

whiA

Organism
Streptococcus pneumoniae (strain CGSP14)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (10 Jun 2008)
      Previous versions | rss
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    Functioni

    May be required for sporulation.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi272 – 30332H-T-H motifUniRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. endonuclease activity Source: InterPro

    GO - Biological processi

    1. regulation of sporulation Source: UniProtKB-HAMAP
    2. regulation of transcription, DNA-templated Source: UniProtKB-KW
    3. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Enzyme and pathway databases

    BioCyciSPNE516950:GI38-1561-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative sporulation transcription regulator WhiAUniRule annotation
    Gene namesi
    Name:whiAUniRule annotation
    Ordered Locus Names:SPCG_1549
    OrganismiStreptococcus pneumoniae (strain CGSP14)
    Taxonomic identifieri516950 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000001682: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 303303Putative sporulation transcription regulator WhiAPRO_0000376579Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi516950.SPCG_1549.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the WhiA transcriptional regulatory family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1481.
    HOGENOMiHOG000040187.
    KOiK09762.
    OMAiHKFMLDA.
    OrthoDBiEOG68WR87.

    Family and domain databases

    Gene3Di3.10.28.10. 1 hit.
    HAMAPiMF_01420. HTH_type_WhiA.
    InterProiIPR027434. Homing_endonucl.
    IPR018478. Sporu_reg_WhiA_N_dom.
    IPR003802. Sporulation_regulator_WhiA.
    IPR023054. Sporulation_regulator_WhiA_C.
    [Graphical view]
    PfamiPF02650. HTH_WhiA. 1 hit.
    PF10298. WhiA_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF55608. SSF55608. 1 hit.
    TIGRFAMsiTIGR00647. MG103. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B2IR82-1 [UniParc]FASTAAdd to Basket

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    MSFTVAVKEE ILGQHHLSRH ELSAIIKMSG SIGLSTSGLT LSVVTENAKL    50
    ARHLYESFLH FYEIKSEIRH HQRSNLRKNR VYTVFTDEKV QDLLSDLHLA 100
    DSFFGLETGI DEAILSDEEA GRAYLCGAFL ANGSIRDPES GKYQLEISSV 150
    YLDHAQGIAS LLQQFLLDAK VLERKKGAVT YLQRAEDIMD FLIVIGAMQA 200
    RDDFERVKIL RETRNDLNRA NNAETANIAR TVSASMKTIN NISKIKDIMG 250
    LENLPVDLQE VAQLRIQHPD YSIQQLADSL STPLTKSGVN HRLRKINKIA 300
    DEL 303
    Length:303
    Mass (Da):34,062
    Last modified:June 10, 2008 - v1
    Checksum:iAC20DED7D3138041
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001033 Genomic DNA. Translation: ACB90801.1.
    RefSeqiYP_001836266.1. NC_010582.1.

    Genome annotation databases

    EnsemblBacteriaiACB90801; ACB90801; SPCG_1549.
    GeneIDi6217597.
    KEGGispw:SPCG_1549.
    PATRICi19679400. VBIStrPne123335_1657.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001033 Genomic DNA. Translation: ACB90801.1 .
    RefSeqi YP_001836266.1. NC_010582.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 516950.SPCG_1549.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACB90801 ; ACB90801 ; SPCG_1549 .
    GeneIDi 6217597.
    KEGGi spw:SPCG_1549.
    PATRICi 19679400. VBIStrPne123335_1657.

    Phylogenomic databases

    eggNOGi COG1481.
    HOGENOMi HOG000040187.
    KOi K09762.
    OMAi HKFMLDA.
    OrthoDBi EOG68WR87.

    Enzyme and pathway databases

    BioCyci SPNE516950:GI38-1561-MONOMER.

    Family and domain databases

    Gene3Di 3.10.28.10. 1 hit.
    HAMAPi MF_01420. HTH_type_WhiA.
    InterProi IPR027434. Homing_endonucl.
    IPR018478. Sporu_reg_WhiA_N_dom.
    IPR003802. Sporulation_regulator_WhiA.
    IPR023054. Sporulation_regulator_WhiA_C.
    [Graphical view ]
    Pfami PF02650. HTH_WhiA. 1 hit.
    PF10298. WhiA_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55608. SSF55608. 1 hit.
    TIGRFAMsi TIGR00647. MG103. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14."
      Ding F., Tang P., Hsu M.-H., Cui P., Hu S., Yu J., Chiu C.-H.
      BMC Genomics 10:158-158(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CGSP14.

    Entry informationi

    Entry nameiWHIA_STRPS
    AccessioniPrimary (citable) accession number: B2IR82
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 26, 2009
    Last sequence update: June 10, 2008
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3