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B2IPY4

- GLGA_STRPS

UniProt

B2IPY4 - GLGA_STRPS

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Protein

Glycogen synthase

Gene

glgA

Organism
Streptococcus pneumoniae (strain CGSP14)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

  1. starch synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciSPNE516950:GI38-1167-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:SPCG_1156
OrganismiStreptococcus pneumoniae (strain CGSP14)
Taxonomic identifieri516950 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000001682: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 477477Glycogen synthasePRO_1000126106Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi516950.SPCG_1156.

Structurei

3D structure databases

ProteinModelPortaliB2IPY4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiPYHDESQ.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

B2IPY4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKILFVAAEG APFSKTGGLG DVIGALPKSL VKAGHEVAVI LPYYDMVEAK
60 70 80 90 100
FGNQIEDVLH FEVSVGWRRQ YCGIKKTVLN GVTFYFIDNQ YYFFRGHVYG
110 120 130 140 150
DFDDGERFAF FQLAAIEAME RIDFIPDLLH VHDYHTAMIP FLLKEKYRWI
160 170 180 190 200
QAYEDIETVL TIHNLEFQGQ FSEGMLGDLF GVGFERYADG TLRWNNCLNW
210 220 230 240 250
MKAGILYANR VSTVSPSYAH EIMTSQFGCN LDQILKMESG KVSGIVNGID
260 270 280 290 300
ADLYNPQTDA LLDYHFNQED LSGKAKNKAK LQERVGLPVR ADVPLVGIVS
310 320 330 340 350
RLTRQKGFDV VVESLHHILQ EDVQIVLLGT GDPAFEGAFS WFAQIYPDKL
360 370 380 390 400
STNITFDVKL AQEIYAACDL FLMPSRFEPC GLSQMMAMRY GTLPLVHEVG
410 420 430 440 450
GLRDTVRAFN PIEGSGTGFS FDNLSPYWLN WTFQTALDLY RNHPDIWRNL
460 470
QKQAMESDFS WDTACKSYLD LYHSLVN
Length:477
Mass (Da):54,159
Last modified:June 10, 2008 - v1
Checksum:i08C2D4911FCEA94F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001033 Genomic DNA. Translation: ACB90408.1.
RefSeqiYP_001835873.1. NC_010582.1.

Genome annotation databases

EnsemblBacteriaiACB90408; ACB90408; SPCG_1156.
GeneIDi6217708.
KEGGispw:SPCG_1156.
PATRICi19678568. VBIStrPne123335_1240.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001033 Genomic DNA. Translation: ACB90408.1 .
RefSeqi YP_001835873.1. NC_010582.1.

3D structure databases

ProteinModelPortali B2IPY4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 516950.SPCG_1156.

Protein family/group databases

CAZyi GT5. Glycosyltransferase Family 5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACB90408 ; ACB90408 ; SPCG_1156 .
GeneIDi 6217708.
KEGGi spw:SPCG_1156.
PATRICi 19678568. VBIStrPne123335_1240.

Phylogenomic databases

eggNOGi COG0297.
HOGENOMi HOG000294940.
KOi K00703.
OMAi PYHDESQ.
OrthoDBi EOG6JTC6Z.

Enzyme and pathway databases

UniPathwayi UPA00164 .
BioCyci SPNE516950:GI38-1167-MONOMER.

Family and domain databases

HAMAPi MF_00484. Glycogen_synth.
InterProi IPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view ]
Pfami PF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR02095. glgA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14."
    Ding F., Tang P., Hsu M.-H., Cui P., Hu S., Yu J., Chiu C.-H.
    BMC Genomics 10:158-158(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CGSP14.

Entry informationi

Entry nameiGLGA_STRPS
AccessioniPrimary (citable) accession number: B2IPY4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 10, 2008
Last modified: October 1, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3