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B2IPY4

- GLGA_STRPS

UniProt

B2IPY4 - GLGA_STRPS

Protein

Glycogen synthase

Gene

glgA

Organism
Streptococcus pneumoniae (strain CGSP14)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 1 (10 Jun 2008)
      Previous versions | rss
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    Functioni

    Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

    Catalytic activityi

    ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei15 – 151ADP-glucoseUniRule annotation

    GO - Molecular functioni

    1. starch synthase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycogen biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Glycogen biosynthesis

    Enzyme and pathway databases

    BioCyciSPNE516950:GI38-1167-MONOMER.
    UniPathwayiUPA00164.

    Protein family/group databases

    CAZyiGT5. Glycosyltransferase Family 5.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
    Alternative name(s):
    Starch [bacterial glycogen] synthaseUniRule annotation
    Gene namesi
    Name:glgAUniRule annotation
    Ordered Locus Names:SPCG_1156
    OrganismiStreptococcus pneumoniae (strain CGSP14)
    Taxonomic identifieri516950 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000001682: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 477477Glycogen synthasePRO_1000126106Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi516950.SPCG_1156.

    Structurei

    3D structure databases

    ProteinModelPortaliB2IPY4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0297.
    HOGENOMiHOG000294940.
    KOiK00703.
    OMAiPYHDESQ.
    OrthoDBiEOG6JTC6Z.

    Family and domain databases

    HAMAPiMF_00484. Glycogen_synth.
    InterProiIPR001296. Glyco_trans_1.
    IPR011835. Glycogen/starch_synth.
    IPR013534. Starch_synth_cat_dom.
    [Graphical view]
    PfamiPF08323. Glyco_transf_5. 1 hit.
    PF00534. Glycos_transf_1. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR02095. glgA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B2IPY4-1 [UniParc]FASTAAdd to Basket

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    MKILFVAAEG APFSKTGGLG DVIGALPKSL VKAGHEVAVI LPYYDMVEAK    50
    FGNQIEDVLH FEVSVGWRRQ YCGIKKTVLN GVTFYFIDNQ YYFFRGHVYG 100
    DFDDGERFAF FQLAAIEAME RIDFIPDLLH VHDYHTAMIP FLLKEKYRWI 150
    QAYEDIETVL TIHNLEFQGQ FSEGMLGDLF GVGFERYADG TLRWNNCLNW 200
    MKAGILYANR VSTVSPSYAH EIMTSQFGCN LDQILKMESG KVSGIVNGID 250
    ADLYNPQTDA LLDYHFNQED LSGKAKNKAK LQERVGLPVR ADVPLVGIVS 300
    RLTRQKGFDV VVESLHHILQ EDVQIVLLGT GDPAFEGAFS WFAQIYPDKL 350
    STNITFDVKL AQEIYAACDL FLMPSRFEPC GLSQMMAMRY GTLPLVHEVG 400
    GLRDTVRAFN PIEGSGTGFS FDNLSPYWLN WTFQTALDLY RNHPDIWRNL 450
    QKQAMESDFS WDTACKSYLD LYHSLVN 477
    Length:477
    Mass (Da):54,159
    Last modified:June 10, 2008 - v1
    Checksum:i08C2D4911FCEA94F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001033 Genomic DNA. Translation: ACB90408.1.
    RefSeqiYP_001835873.1. NC_010582.1.

    Genome annotation databases

    EnsemblBacteriaiACB90408; ACB90408; SPCG_1156.
    GeneIDi6217708.
    KEGGispw:SPCG_1156.
    PATRICi19678568. VBIStrPne123335_1240.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001033 Genomic DNA. Translation: ACB90408.1 .
    RefSeqi YP_001835873.1. NC_010582.1.

    3D structure databases

    ProteinModelPortali B2IPY4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 516950.SPCG_1156.

    Protein family/group databases

    CAZyi GT5. Glycosyltransferase Family 5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACB90408 ; ACB90408 ; SPCG_1156 .
    GeneIDi 6217708.
    KEGGi spw:SPCG_1156.
    PATRICi 19678568. VBIStrPne123335_1240.

    Phylogenomic databases

    eggNOGi COG0297.
    HOGENOMi HOG000294940.
    KOi K00703.
    OMAi PYHDESQ.
    OrthoDBi EOG6JTC6Z.

    Enzyme and pathway databases

    UniPathwayi UPA00164 .
    BioCyci SPNE516950:GI38-1167-MONOMER.

    Family and domain databases

    HAMAPi MF_00484. Glycogen_synth.
    InterProi IPR001296. Glyco_trans_1.
    IPR011835. Glycogen/starch_synth.
    IPR013534. Starch_synth_cat_dom.
    [Graphical view ]
    Pfami PF08323. Glyco_transf_5. 1 hit.
    PF00534. Glycos_transf_1. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR02095. glgA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14."
      Ding F., Tang P., Hsu M.-H., Cui P., Hu S., Yu J., Chiu C.-H.
      BMC Genomics 10:158-158(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CGSP14.

    Entry informationi

    Entry nameiGLGA_STRPS
    AccessioniPrimary (citable) accession number: B2IPY4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: June 10, 2008
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3