B2IJT2 (G6PI_BEII9) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glucose-6-phosphate isomerase
Short name=GPI
EC=5.3.1.9

Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI

Gene names

Name:	pgi
Ordered Locus Names:	Bind_2735

Organism

Beijerinckia indica subsp. indica (strain ATCC 9039 / DSM 1715 / NCIB 8712) [Complete proteome] [HAMAP]

Taxonomic identifier

395963 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Beijerinckiaceae › Beijerinckia

Protein attributes

Sequence length	547 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473
Pathway	Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_00473 Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473
Subcellular location	Cytoplasm By similarity HAMAP MF_00473.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: UniProtKB-KW glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 547	547	Glucose-6-phosphate isomerase HAMAP MF_00473		PRO_1000206359
Sites
	Active site	382	1	By similarity
	Active site	510	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	B2IJT2 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: C3CA1174BA02F1A6	FASTA	547	60,150
	10 20 30 40 50 60 MNRDEVAKTF AALKAHREAS QETIADLFRV DPNRFENFHI KLDDVLFDYS KHRVTRTTLD 70 80 90 100 110 120 LLFALARAAG VEDRRSQLFD GAAVNITEHR PALHMALRKL DGAPVLAEGK DVMPEVLAER 130 140 150 160 170 180 QKIFTFAEAI RKGTIKAANG ERFTDIVNIG IGGSDLGPRM VVTALAPFVA DHLTMHFVSN 190 200 210 220 230 240 VDGADLGDTL KKLPLATTLF IVCSKTFTTL ETMTNAQTAR EAVAEKLGEA AVADHFCAVS 250 260 270 280 290 300 TQLDKIAAFG IKSDRVFGFW DWVGGRYSVW SAIGLSVVIA IGAEKFEKFL LGGQDIDQHF 310 320 330 340 350 360 QTAPLESNVP VIMALLEIWY RDLWDYATRA VIPYDERMHR FSAYLQQLEM ESNGKSVQLS 370 380 390 400 410 420 GAPVTESTSP VVWGEPGTNG QHAFFQMLHQ GTEIVPIDFL VAAQPSGADA KHHQLLVANC 430 440 450 460 470 480 LAQSQALMQG RSLEDVKTLL TAQGLDTAAV NTLAPHKVFP GNRPSSTFLY KRLSPRVLGQ 490 500 510 520 530 540 LIALYEHKVF VEGVIWNVDS FDQWGVELGK ELANKLTPII RDSEASLEGL DGSTAGLIGE IRKHKKG

References

[1]

"Complete sequence of chromosome of Beijerinckia indica subsp. indica ATCC 9039." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., LaButti K., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Dunfield P.F., Dedysh S.N. , Liesack W., Saw J.H., Alam M., Chen Y., Murrell J.C., Richardson P. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 9039 / DSM 1715 / NCIB 8712.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001016 Genomic DNA. Translation: ACB96307.1.
RefSeq	YP_001833796.1. NC_010581.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B2IJT2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6201335.
GenomeReviews	Gene locus Bind_2735 in contig CP001016_GR.
KEGG	bid:Bind_2735.
PATRIC	21088435. VBIBeiInd21058_3137.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG352954.
OMA	NSLPAWT.
ProtClustDB	CLSK2405765.
Family and domain databases
HAMAP	MF_00473. G6P_isomerase. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR023096. G6P_Isomerase_C. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
Gene3D	G3DSA:1.10.1390.10. G6P_Isomerase_C. 1 hit.
KO	K01810.
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI_BEII9

Accession

Primary (citable) accession number: B2IJT2

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	June 10, 2008
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program