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Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Beijerinckia indica subsp. indica (strain ATCC 9039 / DSM 1715 / NCIB 8712)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi489MagnesiumUniRule annotation1
Metal bindingi495MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, RNA-binding, Transferase
LigandMagnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotation
Ordered Locus Names:Bind_3192
OrganismiBeijerinckia indica subsp. indica (strain ATCC 9039 / DSM 1715 / NCIB 8712)
Taxonomic identifieri395963 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBeijerinckiaceaeBeijerinckia
Proteomesi
  • UP000001695 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003818661 – 715Polyribonucleotide nucleotidyltransferaseAdd BLAST715

Proteomic databases

PRIDEiB2ICY4

Interactioni

Protein-protein interaction databases

STRINGi395963.Bind_3192

Structurei

3D structure databases

ProteinModelPortaliB2ICY4
SMRiB2ICY4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini556 – 615KHUniRule annotationAdd BLAST60
Domaini625 – 693S1 motifUniRule annotationAdd BLAST69

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C62 Bacteria
COG1185 LUCA
HOGENOMiHOG000218327
KOiK00962
OMAiRYMHNYN
OrthoDBiPOG091H00M0

Family and domain databases

Gene3Di3.30.1370.10, 1 hit
3.30.230.70, 2 hits
HAMAPiMF_01595 PNPase, 1 hit
InterProiView protein in InterPro
IPR001247 ExoRNase_PH_dom1
IPR015847 ExoRNase_PH_dom2
IPR036345 ExoRNase_PH_dom2_sf
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
IPR012340 NA-bd_OB-fold
IPR012162 PNPase
IPR027408 PNPase/RNase_PH_dom_sf
IPR015848 PNPase_PH_RNA-bd_bac/org-type
IPR020568 Ribosomal_S5_D2-typ_fold
IPR022967 S1_dom
IPR003029 S1_domain
PANTHERiPTHR11252 PTHR11252, 1 hit
PfamiView protein in Pfam
PF00013 KH_1, 1 hit
PF03726 PNPase, 1 hit
PF01138 RNase_PH, 2 hits
PF03725 RNase_PH_C, 1 hit
PF00575 S1, 1 hit
PIRSFiPIRSF005499 PNPase, 1 hit
SMARTiView protein in SMART
SM00322 KH, 1 hit
SM00316 S1, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
SSF54211 SSF54211, 2 hits
SSF54791 SSF54791, 1 hit
SSF55666 SSF55666, 2 hits
TIGRFAMsiTIGR03591 polynuc_phos, 1 hit
PROSITEiView protein in PROSITE
PS50084 KH_TYPE_1, 1 hit
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

B2ICY4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHMFEIHREE IEWAGRKLVL ETGKIARQAD GAIFATYGET TVLATVVSAK
60 70 80 90 100
SVKPGVDFFP LTVNYQEKAF AAGRIPGGYF KREGRPSERE TLVSRLIDRP
110 120 130 140 150
IRPLFPEGYR NETQVIVTVL AHDLENDPDI LSMVASSAAL TLSGVPFMGP
160 170 180 190 200
VGAARVAYVN GQYKINPTLD EVKDTALDLV VAGTSDAVLM VESEAKELSE
210 220 230 240 250
DVMLGAVMAG HSSFQPVIDA IIRLAEKAAK EPRDLILPDK TEVEVAVLAI
260 270 280 290 300
AENDLREAYK ITSKQDRYAA VDAVKAKVFG DLLPAEGEAK FPKDLVAEVF
310 320 330 340 350
HDLQAKVVRW NILDNGIRID GRDVKTVRPI LAEVGILPRA HGSALFTRGE
360 370 380 390 400
TQALVVATLG TGEDEQLIDN LEGTYRERFL LHYNFPPYSV GEAGRMGSPG
410 420 430 440 450
RREIGHGKLA WRAIHPMLPT PAEFPYTIRV VSEITESNGS SSMATVCGSS
460 470 480 490 500
LALMDAGVPL KRPTAGIAMG LILEGERYAV LSDILGDEDH LGDMDFKVAG
510 520 530 540 550
TEEGITSLQM DIKITGINEE IMRVALGQAK EGRLHILGEM AKAITGARAE
560 570 580 590 600
LGEFAPRIET LRIPTEKIRE VIGTGGKVIR EICEKTGAKI NIEDDGTVKV
610 620 630 640 650
ASSDGNSIKA AINWIKSIAT DPEVGHIYDG TVVKVVDFGA FVNFFGSKDG
660 670 680 690 700
LVHISQLAKG RVAKTSDVVK EGDKVKVKLL GFDDRGKVRL SMRLVDQETG
710
EDLEGKEPPQ AEAGE
Length:715
Mass (Da):77,499
Last modified:June 10, 2008 - v1
Checksum:i5E5E86D4AB815143
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001016 Genomic DNA Translation: ACB96752.1

Genome annotation databases

EnsemblBacteriaiACB96752; ACB96752; Bind_3192
KEGGibid:Bind_3192

Similar proteinsi

Entry informationi

Entry nameiPNP_BEII9
AccessioniPrimary (citable) accession number: B2ICY4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 1, 2009
Last sequence update: June 10, 2008
Last modified: May 23, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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