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Protein

Elongation factor Tu

Gene

tuf

Organism
Xylella fastidiosa (strain M23)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi81 – 855GTPUniRule annotation
Nucleotide bindingi136 – 1394GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotationImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciXFAS405441:GJJI-2146-MONOMER.
XFAS405441:GJJI-2160-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Ordered Locus Names:XfasM23_2101Imported, XfasM23_2114Imported
OrganismiXylella fastidiosa (strain M23)Imported
Taxonomic identifieri405441 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXylella
ProteomesiUP000001698: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi405441.XfasM23_2114.

Structurei

3D structure databases

ProteinModelPortaliB2IA63.
SMRiB2IA63. Positions 2-395.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0050.
HOGENOMiHOG000229290.
KOiK02358.
OMAiIKMTGEL.
OrthoDBiEOG6R5C6X.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2IA63-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQDKFKRTK LHVNVGTIGH VDHGKTTLTA ALTKVGAERF GGEFKAYDAI
60 70 80 90 100
DAAPEEKARG ITISTAHVEY ETEVRHYAHV DCPGHADYVK NMITGAAQMD
110 120 130 140 150
GAILVCSAAD GPMPQTREHI LLARQVGVPY IVVFLNKADM VDDAELLELV
160 170 180 190 200
EMEVRELLSK YDFPGDDTPI VRGSALKALE GDQSEIGVPA IIRLAEALDT
210 220 230 240 250
HIPNPERAID RPFLMPVEDV FSISGRGTVV TGRIECGVIK VGDEVEIVGI
260 270 280 290 300
RPTSKTIVTG VEMFRKLLDQ GQAGDNAGLL LRGTKRDEVE RGQVLAKPGC
310 320 330 340 350
IKAHKEFEAE VYVLSKEEGG RHTPFFNGYT PQFYMRTTDI TGKVCLPEGV
360 370 380 390
EMVMPGDNVK VTVSLINPVA MGEGQRFAIR EGGRTVGAGV VSKVIG
Length:396
Mass (Da):42,906
Last modified:June 10, 2008 - v1
Checksum:i8ACF62D38F337276
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001011 Genomic DNA. Translation: ACB93499.1.
CP001011 Genomic DNA. Translation: ACB93512.1.
RefSeqiYP_001830773.1. NC_010577.1.
YP_001830786.1. NC_010577.1.

Genome annotation databases

EnsemblBacteriaiACB93499; ACB93499; XfasM23_2101.
ACB93512; ACB93512; XfasM23_2114.
GeneIDi6202653.
6203576.
KEGGixfn:XfasM23_2101.
xfn:XfasM23_2114.
PATRICi24146917. VBIXylFas85937_2616.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001011 Genomic DNA. Translation: ACB93499.1.
CP001011 Genomic DNA. Translation: ACB93512.1.
RefSeqiYP_001830773.1. NC_010577.1.
YP_001830786.1. NC_010577.1.

3D structure databases

ProteinModelPortaliB2IA63.
SMRiB2IA63. Positions 2-395.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi405441.XfasM23_2114.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACB93499; ACB93499; XfasM23_2101.
ACB93512; ACB93512; XfasM23_2114.
GeneIDi6202653.
6203576.
KEGGixfn:XfasM23_2101.
xfn:XfasM23_2114.
PATRICi24146917. VBIXylFas85937_2616.

Phylogenomic databases

eggNOGiCOG0050.
HOGENOMiHOG000229290.
KOiK02358.
OMAiIKMTGEL.
OrthoDBiEOG6R5C6X.

Enzyme and pathway databases

BioCyciXFAS405441:GJJI-2146-MONOMER.
XFAS405441:GJJI-2160-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Whole genome sequences of two Xylella fastidiosa strains (M12 and M23) causing almond leaf scorch disease in California."
    Chen J., Xie G., Han S., Chertkov O., Sims D., Civerolo E.L.
    J. Bacteriol. 192:4534-4534(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: M23Imported.

Entry informationi

Entry nameiB2IA63_XYLF2
AccessioniPrimary (citable) accession number: B2IA63
Entry historyi
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: March 4, 2015
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.