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B2I9G0 (AROB_XYLF2) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:XfasM23_0610
OrganismXylella fastidiosa (strain M23) [Complete proteome] [HAMAP]
Taxonomic identifier405441 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xylella

Protein attributes

Sequence length370 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm By similarity HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3703703-dehydroquinate synthase HAMAP MF_00110
PRO_1000094656

Sequences

Sequence LengthMass (Da)Tools
B2I9G0 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: B31F8371A34063A9

FASTA37039,408
        10         20         30         40         50         60 
MTTPTPLRSV TVNTPPPYTI AIGPGLLHDP PRLAATIRGR HALILSDSEV APRYAAQLHE 

        70         80         90        100        110        120 
TLLRARPDLH LNVFTLPAGE TSKSLENFGA AIAQLATLGA TRDACLFALG GGVIGDLAGF 

       130        140        150        160        170        180 
TAACWMRGID YVQVPTTLLA MVDSSVGGKT AVDIPQGKNM VGAFHPPRAV IADTDTLATL 

       190        200        210        220        230        240 
PLRELRAGLS EVIKYGAIRD PVFFHWLQTT REALLARDPA ALAQAIARSC EHKADIVGRD 

       250        260        270        280        290        300 
PLEKGERVLL NLGHTFGHAI ETTQGYSTPG SNNLNHGEAV AVGMVLAARL SNTLGLAPAE 

       310        320        330        340        350        360 
DTETLKNLLD AYGLPTVLPS GLTPEMLLER MRLDKKNIAG RLRLVLWRGI GHAEAVPDVD 

       370 
EAAVRQILAN

« Hide

References

[1]"Whole genome sequences of two Xylella fastidiosa strains (M12 and M23) causing almond leaf scorch disease in California."
Chen J., Xie G., Han S., Chertkov O., Sims D., Civerolo E.L.
J. Bacteriol. 192:4534-4534(2010) [PubMed: 20601474] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: M23.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001011 Genomic DNA. Translation: ACB92054.1.
RefSeqYP_001829328.1. NC_010577.1.

3D structure databases

ProteinModelPortalB2I9G0.
ModBaseSearch...

Protein-protein interaction databases

STRINGB2I9G0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6203946.
GenomeReviewsGene locus XfasM23_0610 in contig CP001011_GR.
KEGGxfn:XfasM23_0610.
PATRIC24143201. VBIXylFas85937_0779.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG632303.
OMAVMALEMS.
ProtClustDBPRK00002.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_XYLF2
AccessionPrimary (citable) accession number: B2I9G0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: June 10, 2008
Last modified: January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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