B2I9E4 (DCD_XYLF2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	XfasM23_2000

Organism

Xylella fastidiosa (strain M23) [Complete proteome] [HAMAP]

Taxonomic identifier

405441 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xylella › Xylella fastidiosa

Protein attributes

Sequence length	191 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 191	191	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000096462

Sequences

	Sequence		Length	Mass (Da)
	B2I9E4 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: D10EFC38BAFC7F4E	FASTA	191	21,543
	10 20 30 40 50 60 MSIKSDRWIR HMAKQHGMIA PFEPGQIKQN TTGQRIVSYG TSSYGYDVRC SHEFKIFTNI 70 80 90 100 110 120 NSTIVDPKQF DNGSFIDVES DVCIIPPNSF ALARTIEYFR IPRNVLVICL GKSTYARCGI 130 140 150 160 170 180 IVNVTPLEPE WEGHVTLEFS NTTPLPARIY ANEGVAQMLF LQADPDDVCE TSYRDRNGKY 190 QGQTGVTLPR T

References

[1]

"Whole genome sequences of two Xylella fastidiosa strains (M12 and M23) causing almond leaf scorch disease in California." Chen J., Xie G., Han S., Chertkov O., Sims D., Civerolo E.L. J. Bacteriol. 192:4534-4534(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: M23.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001011 Genomic DNA. Translation: ACB93399.1.
RefSeq	YP_001830673.1. NC_010577.1.
3D structure databases
ProteinModelPortal	B2I9E4.
ModBase	Search...
Protein-protein interaction databases
STRING	405441.XfasM23_2000.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACB93399; ACB93399; XfasM23_2000.
GeneID	6203354.
KEGG	xfn:XfasM23_2000.
PATRIC	24146646. VBIXylFas85937_2483.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228600.
KO	K01494.
OMA	RSVLTVC.
ProtClustDB	PRK00416.
Enzyme and pathway databases
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_XYLF2

Accession

Primary (citable) accession number: B2I9E4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	June 10, 2008
Last modified:	May 1, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program