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Protein

Glycerol-3-phosphate acyltransferase

Gene

plsB

Organism
Xylella fastidiosa (strain M23)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate.UniRule annotation

Pathwayi: CDP-diacylglycerol biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate.UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Glycerol-3-phosphate acyltransferase (plsB)
  2. no protein annotated in this organism
  3. Phosphatidate cytidylyltransferase (XfasM23_0325)
This subpathway is part of the pathway CDP-diacylglycerol biosynthesis, which is itself part of Phospholipid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate, the pathway CDP-diacylglycerol biosynthesis and in Phospholipid metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

BioCyciXFAS405441:GJJI-328-MONOMER.
UniPathwayiUPA00557; UER00612.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate acyltransferaseUniRule annotation (EC:2.3.1.15UniRule annotation)
Short name:
GPATUniRule annotation
Gene namesi
Name:plsBUniRule annotation
Ordered Locus Names:XfasM23_0310
OrganismiXylella fastidiosa (strain M23)
Taxonomic identifieri405441 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXylella
Proteomesi
  • UP000001698 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation; Cytoplasmic side UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 863863Glycerol-3-phosphate acyltransferasePRO_1000123101Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliB2I7N1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi343 – 3486HXXXXD motif

Domaini

The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.UniRule annotation

Sequence similaritiesi

Belongs to the GPAT/DAPAT family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000218231.
KOiK00631.
OMAiEVIYVPC.

Family and domain databases

HAMAPiMF_00393. Glyc3P_acyltrans. 1 hit.
InterProiIPR022284. GPAT/DHAPAT.
IPR028354. GPAT_PlsB.
IPR002123. Plipid/glycerol_acylTrfase.
[Graphical view]
PANTHERiPTHR12563. PTHR12563. 2 hits.
PfamiPF01553. Acyltransferase. 1 hit.
[Graphical view]
PIRSFiPIRSF500064. GPAT. 1 hit.
PIRSF000437. GPAT_DHAPAT. 1 hit.
SMARTiSM00563. PlsC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03703. plsB. 1 hit.

Sequencei

Sequence statusi: Complete.

B2I7N1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKKNSPLLP KETTTTQSSV DTSGSSNLTW PVSEHTIRRP LWARLLGQIL
60 70 80 90 100
DPWLDLSIEP EHSVQYNDGR PIIYVLEDYG LCNTLILDKA CRKTKLPSPL
110 120 130 140 150
IPLSGNPLQR KRAYLALSRR SSSNSLIPNQ RGGKTHSDSL ANLLQAHRIR
160 170 180 190 200
DTLDVHLVPV SIFIGRTPDR QSGWFAVLFS ENWALVGRFR RILAILLNGR
210 220 230 240 250
NTIVCFAPPI SVRQTLNEGL PPERTLRKLQ RVLRTHFRRI RETVIGPDLS
260 270 280 290 300
TRRLLVDNVL ATEAVREAIG AQAKRDGTDL SETWRKAQAY AWEIAADYSS
310 320 330 340 350
PVIRSADFLF SHVWNRIYAG VLVHHVDSFK EISPGHEIVY VPSHRSHMDY
360 370 380 390 400
LLLSYCLYKC SIGLPHIVAG INLNLPVVGT LLRKCGAFFI RRSIKGNMLY
410 420 430 440 450
SVVLSEYVAQ LVAGGYSLEY FIEGGRSRTG RLLQPKGGMI MMTVQAFLRQ
460 470 480 490 500
PRRPVLFQPI YIGYEKLMEG TSYLDELSGE PKKKESIWRV FWNIPKVLKQ
510 520 530 540 550
KYGQVVVNFG EPIALNDVLA ELAPEWEGQA LNENEKPAWL SSTVNHLARQ
560 570 580 590 600
IQTRINSAAD VNPINLLALA LLSTPKHAMG EADLIAQITL CKKILLELPY
610 620 630 640 650
SNRVTITPHT PERIIAHAEQ INILTRVHHP LGDVLRVDGD NAVLLSYFRN
660 670 680 690 700
NVLHLFTASA WVACCFKNNR RMSRIALIRL GVGMYPFLQA ELFLPWTEDQ
710 720 730 740 750
FAQHIQQVIE LFVREGLLLS AGNEEEDPLT RNTSQTDEVF RLRAISHSLQ
760 770 780 790 800
QAFERYYITI SILVKNGPGT LSASELESLC QLAAQRLSLL YASTAPEFFD
810 820 830 840 850
KGLFRGFIQK LRELNLVWPD TYSKLLFDER LDTSAKDAQV ILGRELRHTI
860
ERISPEATKP APK
Length:863
Mass (Da):97,619
Last modified:June 10, 2008 - v1
Checksum:iD700BB120F14ECC6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001011 Genomic DNA. Translation: ACB91759.1.
RefSeqiWP_004089351.1. NC_010577.1.

Genome annotation databases

EnsemblBacteriaiACB91759; ACB91759; XfasM23_0310.
KEGGixfn:XfasM23_0310.
PATRICi24142471. VBIXylFas85937_0423.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001011 Genomic DNA. Translation: ACB91759.1.
RefSeqiWP_004089351.1. NC_010577.1.

3D structure databases

ProteinModelPortaliB2I7N1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACB91759; ACB91759; XfasM23_0310.
KEGGixfn:XfasM23_0310.
PATRICi24142471. VBIXylFas85937_0423.

Phylogenomic databases

HOGENOMiHOG000218231.
KOiK00631.
OMAiEVIYVPC.

Enzyme and pathway databases

UniPathwayiUPA00557; UER00612.
BioCyciXFAS405441:GJJI-328-MONOMER.

Family and domain databases

HAMAPiMF_00393. Glyc3P_acyltrans. 1 hit.
InterProiIPR022284. GPAT/DHAPAT.
IPR028354. GPAT_PlsB.
IPR002123. Plipid/glycerol_acylTrfase.
[Graphical view]
PANTHERiPTHR12563. PTHR12563. 2 hits.
PfamiPF01553. Acyltransferase. 1 hit.
[Graphical view]
PIRSFiPIRSF500064. GPAT. 1 hit.
PIRSF000437. GPAT_DHAPAT. 1 hit.
SMARTiSM00563. PlsC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03703. plsB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPLSB_XYLF2
AccessioniPrimary (citable) accession number: B2I7N1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 10, 2008
Last modified: September 7, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.