Reviewed, UniProtKB/Swiss-Prot B2I1P1 (PNCB_ACIBC)

Names and origin

Protein names

Recommended name:
    Nicotinate phosphoribosyltransferase
      Short name=NAPRTase
    EC=2.4.2.11

Gene names

Name:	pncB
Ordered Locus Names:	ACICU_03580

Organism

Acinetobacter baumannii (strain ACICU) [Complete proteome] [HAMAP]

Taxonomic identifier

405416 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	404 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00570
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP MF_00570
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the NAPRTase family.

Ontologies

Keywords
Biological process	Pyridine nucleotide biosynthesis
Cellular component	Cytoplasm
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	NAD biosynthetic process Inferred from electronic annotation. Source: HAMAP nicotinate nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nicotinate phosphoribosyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 404	404	Nicotinate phosphoribosyltransferase HAMAP MF_00570		PRO_1000129458

Sequences

	Sequence		Length	Mass (Da)
	B2I1P1-1 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: E675054A84B7FE9F	FASTA	404	47,299
	10 20 30 40 50 60 MSPIIHSLLD TDLYKFTMLQ VVLHKFPQTH SVYHFRCRNL EDTVYPLVDI LDDLNEQLDH 70 80 90 100 110 120 LCNLKYKEDE LQYLRKLRFI KSDFVDYLEL FQLKRRFIHA SIDEEGRLDI RIEGPMVQAM 130 140 150 160 170 180 MFEIFVLAIV NELYFSRIKT DEVWAEGERR LQAKLELIQQ YEKSQQPNDP PFLVSDFGTR 190 200 210 220 230 240 RRYSFEWQKH VVAAFHNTVP NVFRGTSNVL LAKELNITPI GTMAHEFLQA FQALDVRLRD 250 260 270 280 290 300 FQKAALETWV QEYRGDLGIA LTDVVGMDAF LRDFDLYFAK LFDGLRHDSG DPYEWGDKAY 310 320 330 340 350 360 AHYRKLKIDT KTKMLTFSDG LNLPKAWELH QYFKDRFQVS FGIGTNLTND MGQTPLNIVL 370 380 390 400 KLVECNGQSV AKISDSPGKT MTDNDTFLAY LRQVFQIEEL DEAI

References

[1]

"Whole-genome pyrosequencing of an epidemic multidrug-resistant Acinetobacter baumannii strain belonging to the European clone II group." Iacono M., Villa L., Fortini D., Bordoni R., Imperi F., Bonnal R.J., Sicheritz-Ponten T., De Bellis G., Visca P., Cassone A., Carattoli A. Antimicrob. Agents Chemother. 52:2616-2625(2008) [PubMed: 18411315] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000863 Genomic DNA. Translation: ACC58889.1.
RefSeq	YP_001848236.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6236047.
GenomeReviews	Gene locus ACICU_03580 in contig CP000863_GR.
KEGG	abc:ACICU_03580.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	VGMDAFL.
Family and domain databases
HAMAP	MF_00570. [Tree]
InterPro	IPR006406. Nic_PRibTrfase. IPR015977. Nic_PRibTrfase-like. IPR007229. Nic_PRibTrfase-rel. [Graphical view]
PANTHER	PTHR11098:SF1. NAPRTase. 1 hit.
Pfam	PF04095. NAPRTase. 1 hit. [Graphical view]
PIRSF	PIRSF000484. NAPRT. 1 hit.
TIGRFAMs	TIGR01514. NAPRTase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PNCB_ACIBC

Accession

Primary (citable) accession number: B2I1P1

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	June 10, 2008
Last modified:	November 3, 2009
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)