Reviewed,
UniProtKB/Swiss-Prot B2HUN5 (COAD_ACIBC)
Last modified
November 3, 2009.
Version 12.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Phosphopantetheine adenylyltransferase EC=2.7.7.3 Alternative name(s): Pantetheine-phosphate adenylyltransferase Short name=PPAT Dephospho-CoA pyrophosphorylase | ||||
| Gene names |
| ||||
| Organism | Acinetobacter baumannii (strain ACICU) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 405416 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter |
Protein attributes
| Sequence length | 163 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate By similarity. |
| Catalytic activity | ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA. HAMAP MF_00151 |
| Pathway | Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5. HAMAP MF_00151 |
| Subunit structure | Homohexamer By similarity. |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the bacterial coaD family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Coenzyme A biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Nucleotidyltransferase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | coenzyme A biosynthetic process Inferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW pantetheine-phosphate adenylyltransferase activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 163 | 163 | Phosphopantetheine adenylyltransferase HAMAP MF_00151 | PRO_1000096751 | |||
Sequences
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References
| [1] | "Whole-genome pyrosequencing of an epidemic multidrug-resistant Acinetobacter baumannii strain belonging to the European clone II group." Iacono M., Villa L., Fortini D., Bordoni R., Imperi F., Bonnal R.J., Sicheritz-Ponten T., De Bellis G., Visca P., Cassone A., Carattoli A. Antimicrob. Agents Chemother. 52:2616-2625(2008) [PubMed: 18411315] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| CP000863 Genomic DNA. Translation: ACC56110.1. | |
| RefSeq | YP_001845457.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 6235363. |
| GenomeReviews | Gene locus ACICU_00798 in contig CP000863_GR. |
| KEGG | abc:ACICU_00798. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| OMA | AMSDFEY. |
Family and domain databases | |
| HAMAP | MF_00151. [Tree] |
| InterPro | IPR004821. Cyt_trans_rel. IPR004820. Cytidylyltransf. IPR001980. LPS_biosynth. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view] |
| Gene3D | G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit. |
| Pfam | PF01467. CTP_transf_2. 1 hit. [Graphical view] |
| PRINTS | PR01020. LPSBIOSNTHSS. |
| TIGRFAMs | TIGR01510. coaD_prev_kdtB. 1 hit. TIGR00125. cyt_tran_rel. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | COAD_ACIBC | ||||||||
| Accession | Primary (citable) accession number: B2HUN5 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


