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Reviewed, UniProtKB/Swiss-Prot B2HUI0 (DCD_ACIBC)

Last modified November 3, 2009. Version 10. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13
Gene names
Name: dcd
Ordered Locus Names: ACICU_00743
OrganismAcinetobacter baumannii (strain ACICU) [Complete proteome] [HAMAP]
Taxonomic identifier405416 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacter

Protein attributes

Sequence length189 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

dCTP + H2O = dUTP + NH3. HAMAP MF_00146

Pathway

Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146

Sequence similarities

Belongs to the dCTP deaminase family.

Ontologies

Keywords
   Biological processNucleotide metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processdUTP biosynthetic process

Inferred from electronic annotation. Source: InterPro

pyrimidine ribonucleotide biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Molecular functiondCTP deaminase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 189189Deoxycytidine triphosphate deaminase HAMAP MF_00146
PRO_1000096398

Sequences

Sequence LengthMass (Da)Tools
B2HUI0-1 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: 80F7A026AC9D7CF8

FASTA18921,442
        10         20         30         40         50         60 
MAIKSDRWIR EMSEKHGMIE PYAENQVRFD KNGEKLISYG VSSYGYDVRC AREFKVFTNV 

        70         80         90        100        110        120 
HSAIVDPKNF DEKSFIDIES DVCIIPPNSF ALARTIEYFR IPRNVLTVCL GKSTYARCGI 

       130        140        150        160        170        180 
IVNVTPLEPE WEGHVTLEFS NTTNLPARIY AGEGVAQMLF FESDEVCETS YKDRGGKYQG 


QTGVTLPKT 

« Hide

References

[1]"Whole-genome pyrosequencing of an epidemic multidrug-resistant Acinetobacter baumannii strain belonging to the European clone II group."
Iacono M., Villa L., Fortini D., Bordoni R., Imperi F., Bonnal R.J., Sicheritz-Ponten T., De Bellis G., Visca P., Cassone A., Carattoli A.
Antimicrob. Agents Chemother. 52:2616-2625(2008) [PubMed: 18411315] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000863 Genomic DNA. Translation: ACC56055.1.
RefSeqYP_001845402.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID6237318.
GenomeReviewsGene locus ACICU_00743 in contig CP000863_GR.
KEGGabc:ACICU_00743.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMACAQVLFF.

Family and domain databases

HAMAPMF_00146.
[Tree]
InterProIPR011962. dCTP_deam.
IPR008180. DeoxyUTP_pyroPase_dom.
[Graphical view]
PfamPF00692. dUTPase. 1 hit.
[Graphical view]
TIGRFAMsTIGR02274. dCTP_deam. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDCD_ACIBC
AccessionPrimary (citable) accession number: B2HUI0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: June 10, 2008
Last modified: November 3, 2009
This is version 10 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents