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Protein

Glucose-1-phosphate adenylyltransferase

Gene

glgC

Organism
Mycobacterium marinum (strain ATCC BAA-535 / M)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans.UniRule annotation

Catalytic activityi

ATP + alpha-D-glucose 1-phosphate = diphosphate + ADP-glucose.UniRule annotation

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMMAR216594:GJOB-4258-MONOMER.
UniPathwayiUPA00164.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-1-phosphate adenylyltransferaseUniRule annotation (EC:2.7.7.27UniRule annotation)
Alternative name(s):
ADP-glucose pyrophosphorylaseUniRule annotation
Short name:
ADPGlc PPaseUniRule annotation
ADP-glucose synthaseUniRule annotation
Gene namesi
Name:glgCUniRule annotation
Ordered Locus Names:MMAR_4225
OrganismiMycobacterium marinum (strain ATCC BAA-535 / M)
Taxonomic identifieri216594 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000001190 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 404404Glucose-1-phosphate adenylyltransferasePRO_1000130492Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi216594.MMAR_4225.

Structurei

3D structure databases

ProteinModelPortaliB2HS55.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QQ4. Bacteria.
COG0448. LUCA.
HOGENOMiHOG000278607.
KOiK00975.
OMAiFGCIDSD.
OrthoDBiPOG091H09L2.

Family and domain databases

Gene3Di3.90.550.10. 2 hits.
HAMAPiMF_00624. GlgC. 1 hit.
InterProiIPR005836. ADP_Glu_pyroP_CS.
IPR011831. GlgC.
IPR023049. GlgC_bac.
IPR005835. NTP_transferase_dom.
IPR029044. Nucleotide-diphossugar_trans.
IPR011004. Trimer_LpxA-like.
[Graphical view]
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF51161. SSF51161. 1 hit.
SSF53448. SSF53448. 2 hits.
TIGRFAMsiTIGR02091. glgC. 1 hit.
PROSITEiPS00808. ADP_GLC_PYROPHOSPH_1. 1 hit.
PS00809. ADP_GLC_PYROPHOSPH_2. 1 hit.
PS00810. ADP_GLC_PYROPHOSPH_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2HS55-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MREAPHVLGI VLAGGEGKRL YPLTADRAKP AVPFGGAYRL IDFVLSNLVN
60 70 80 90 100
ARYLRICVLT QYKSHSLDRH ISQNWRLSGL AGEYITPVPA QQRLGPRWYT
110 120 130 140 150
GSADAIYQSL NLIYDEDPDY IVVFGADHVY RMDPEQMVRF HIDSGAGVTV
160 170 180 190 200
AGIRVPRADA SAFGCIDADD AGTIRDFVEK PLEPPGTPDD PTSTFVSMGN
210 220 230 240 250
YVFTTKVLID AIRADADDDH SDHDMGGDII PRLVADGMAA VYDFSNNEVP
260 270 280 290 300
GATDRDRAYW RDVGTLDAFY DAHMDLVSVH PVFNLYNKRW PIRGESENLA
310 320 330 340 350
PAKFVNGGSA QESVVGAGSI ISAASVRNSV LSSNVVVEDG AIVEGSVIMP
360 370 380 390 400
GARVGRGAVV RHAILDKNVV VGPGEMVGVD LDKDRERFAI SAGGVVAVGK

GVWI
Length:404
Mass (Da):43,627
Last modified:June 10, 2008 - v1
Checksum:i8092ADFF4B7140F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000854 Genomic DNA. Translation: ACC42633.1.
RefSeqiWP_012395797.1. NC_010612.1.

Genome annotation databases

EnsemblBacteriaiACC42633; ACC42633; MMAR_4225.
KEGGimmi:MMAR_4225.
PATRICi18069739. VBIMycMar75906_4536.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000854 Genomic DNA. Translation: ACC42633.1.
RefSeqiWP_012395797.1. NC_010612.1.

3D structure databases

ProteinModelPortaliB2HS55.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi216594.MMAR_4225.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACC42633; ACC42633; MMAR_4225.
KEGGimmi:MMAR_4225.
PATRICi18069739. VBIMycMar75906_4536.

Phylogenomic databases

eggNOGiENOG4107QQ4. Bacteria.
COG0448. LUCA.
HOGENOMiHOG000278607.
KOiK00975.
OMAiFGCIDSD.
OrthoDBiPOG091H09L2.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciMMAR216594:GJOB-4258-MONOMER.

Family and domain databases

Gene3Di3.90.550.10. 2 hits.
HAMAPiMF_00624. GlgC. 1 hit.
InterProiIPR005836. ADP_Glu_pyroP_CS.
IPR011831. GlgC.
IPR023049. GlgC_bac.
IPR005835. NTP_transferase_dom.
IPR029044. Nucleotide-diphossugar_trans.
IPR011004. Trimer_LpxA-like.
[Graphical view]
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF51161. SSF51161. 1 hit.
SSF53448. SSF53448. 2 hits.
TIGRFAMsiTIGR02091. glgC. 1 hit.
PROSITEiPS00808. ADP_GLC_PYROPHOSPH_1. 1 hit.
PS00809. ADP_GLC_PYROPHOSPH_2. 1 hit.
PS00810. ADP_GLC_PYROPHOSPH_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLGC_MYCMM
AccessioniPrimary (citable) accession number: B2HS55
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 10, 2008
Last modified: September 7, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.