B2HR26 (B2HR26_MYCMM) Unreviewed, UniProtKB/TrEMBL
Last modified
May 1, 2013.
Version 45.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: N-acetyl-gamma-glutamyl-phosphate reductase HAMAP-Rule MF_00150 Short name=AGPR HAMAP-Rule MF_00150 EC=1.2.1.38 HAMAP-Rule MF_00150 Alternative name(s): N-acetyl-glutamate semialdehyde dehydrogenase HAMAP-Rule MF_00150 | ||||
| Gene names |
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| Organism | Mycobacterium marinum (strain ATCC BAA-535 / M) [Complete proteome] [HAMAP] EMBL ACC40912.1 | ||||
| Taxonomic identifier | 216594 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › ![]() |
Protein attributes
| Sequence length | 350 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH. HAMAP-Rule MF_00150 SAAS SAAS023013 |
| Pathway | Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4. HAMAP-Rule MF_00150 SAAS SAAS023013 |
| Subcellular location | Cytoplasm By similarity HAMAP-Rule MF_00150 SAAS SAAS023013. |
| Sequence similarities | Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. HAMAP-Rule MF_00150 |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Arginine biosynthesis HAMAP-Rule MF_00150 SAAS SAAS023013 |
| Cellular component | Cytoplasm HAMAP-Rule MF_00150 SAAS SAAS023013 |
| Ligand | NADP HAMAP-Rule MF_00150 SAAS SAAS023013 |
| Molecular function | Oxidoreductase HAMAP-Rule MF_00150 SAAS SAAS023013 |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological_process | arginine biosynthetic process Inferred from electronic annotation. Source: HAMAP |
| Cellular_component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular_function | N-acetyl-gamma-glutamyl-phosphate reductase activity Inferred from electronic annotation. Source: HAMAP NAD bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Sites | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Active site | 156 | 1 | By similarity HAMAP-Rule MF_00150 | ||||||
Sequences
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References
| [1] | "Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis." Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K., Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C., Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K., Lord A., Moule S. Cole S.T.Genome Res. 18:729-741(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-535 / M. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000854 Genomic DNA. Translation: ACC40912.1. |
| RefSeq | YP_001850767.1. NC_010612.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 216594.MMAR_2462. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | ACC40912; ACC40912; MMAR_2462. |
| GeneID | 6226728. |
| KEGG | mmi:MMAR_2462. |
| PATRIC | 18065885. VBIMycMar75906_2623. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0002. |
| HOGENOM | HOG000254904. |
| KO | K00145. |
| OMA | VCRIAVH. |
| ProtClustDB | PRK00436. |
Enzyme and pathway databases | |
| BioCyc | MMAR216594:GJOB-2479-MONOMER. |
| UniPathway | UPA00068; UER00108. |
Family and domain databases | |
| Gene3D | 3.40.50.720. 1 hit. |
| HAMAP | MF_00150. ArgC_type1. |
| InterPro | IPR023013. AGPR_AS. IPR000706. AGPR_type-1. IPR016040. NAD(P)-bd_dom. IPR000534. Semialdehyde_DH_NAD-bd. IPR012280. Semialdhyde_DH_dimer_dom. [Graphical view] |
| Pfam | PF01118. Semialdhyde_dh. 1 hit. PF02774. Semialdhyde_dhC. 1 hit. [Graphical view] |
| SMART | SM00859. Semialdhyde_dh. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR01850. argC. 1 hit. |
| PROSITE | PS01224. ARGC. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | B2HR26_MYCMM | ||||||||
| Accession | Primary (citable) accession number: B2HR26 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

Clusters with
