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B2HR20 (B2HR20_MYCMM) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phenylalanine--tRNA ligase alpha chain HAMAP MF_00281
EC=6.1.1.20 HAMAP MF_00281
Alternative name(s):
Phenylalanyl-tRNA synthetase alpha chain HAMAP MF_00281
Gene names
Name:pheS HAMAP MF_00281 EMBL ACC40906.1
Ordered Locus Names:MMAR_2456
OrganismMycobacterium marinum (strain ATCC BAA-535 / M) [Complete proteome] [HAMAP]
Taxonomic identifier216594 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length347 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe). HAMAP MF_00281

Cofactor

Binds 2 magnesium ions per tetramer By similarity. HAMAP MF_00281

Subunit structure

Tetramer of two alpha and two beta chains By similarity. HAMAP MF_00281

Subcellular location

Cytoplasm By similarity HAMAP MF_00281.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily. HAMAP MF_00281

Sequences

Sequence LengthMass (Da)Tools
B2HR20 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: 1D0CC6F8012D33E4

FASTA34738,215
        10         20         30         40         50         60 
MGDQPVDLSP QGLANVVKLA HQAFASADDL EALARAKTEH LGDRSPLALA RQSLGTLPKE 

        70         80         90        100        110        120 
QRADAGKAVN LARGDAQCSY DERLAVLRAE RDAAVLVAER IDVTLPSTRQ PTGARHPITI 

       130        140        150        160        170        180 
LAEHIADTFI AMGWELAEGP EVETEQFNFD ALNFPPDHPA RSEQDTFYIA PEDSRQLLRT 

       190        200        210        220        230        240 
HTSPVQVRTL LERELPVYII SIGRTFRTDE LDATHTPVFH QVEGLAVDRG LTMAHLRGTL 

       250        260        270        280        290        300 
DAFARSEFGP LARTRIRPHF FPFTEPSAEV DVWFANKKGG ADWVEWGGCG MVHPNVLRAA 

       310        320        330        340 
GIDPEVYSGF AFGMGLERTL QFRNGIPDMR DMVEGDVRFS LPFGVGA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000854 Genomic DNA. Translation: ACC40906.1.
RefSeqYP_001850761.1. NC_010612.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB2HR20.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000031190; EBMYCP00000029630; EBMYCG00000031185.
GeneID6226722.
GenomeReviewsGene locus MMAR_2456 in contig CP000854_GR.
KEGGmmi:MMAR_2456.
PATRIC18065873. VBIMycMar75906_2617.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000016426.
HOGENOMHBG284353.
OMAFRASYFP.
ProtClustDBPRK00488.

Family and domain databases

HAMAPMF_00281. Phe_tRNA_synth_alpha1.
[Tree]
InterProIPR006195. aa-tRNA-synth_II.
IPR004529. Phe-tRNA-synth_IIc_asu.
IPR004188. Phe-tRNA_synth_II_N.
IPR022911. Phe_tRNA_synth_alpha1_bac.
IPR002319. Phenylalanyl-tRNA_Synthase.
IPR010978. tRNA-bd_arm.
[Graphical view]
KOK01889.
PfamPF02912. Phe_tRNA-synt_N. 1 hit.
PF01409. tRNA-synt_2d. 1 hit.
[Graphical view]
SUPFAMSSF46589. tRNA_binding_arm. 1 hit.
TIGRFAMsTIGR00468. PheS. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB2HR20_MYCMM
AccessionPrimary (citable) accession number: B2HR20
Entry history
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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