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B2HQX7 (TRPC_MYCMM) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Indole-3-glycerol phosphate synthase
Short name=IGPS
EC=4.1.1.48
Gene names
Name:trpC
Ordered Locus Names:MMAR_2413
OrganismMycobacterium marinum (strain ATCC BAA-535 / M) [Complete proteome] [HAMAP]
Taxonomic identifier216594 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length272 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134_B

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134_B

Sequence similarities

Belongs to the TrpC family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 272272Indole-3-glycerol phosphate synthase HAMAP MF_00134_B
PRO_1000095872

Sequences

Sequence LengthMass (Da)Tools
B2HQX7 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: 51743B48EC48F8F6

FASTA27228,115
        10         20         30         40         50         60 
MSPATVLDSI LEGVRADVAA REALVGMTEI KAAAAAAPPP LDVMAALRQP GIGVIAEVKR 

        70         80         90        100        110        120 
ASPSAGSLAP ITDPAKLARA YEDGGARIIS VLTEGRRFQG SLDDLDAVRA AVSIPLLRKD 

       130        140        150        160        170        180 
FVVQPYQIHE ARAHGADMLL LIVAALDQSA LVSMLDRTES LGMTALVEVH TEQEADRALK 

       190        200        210        220        230        240 
AGAKVIGVNA RDLTTLEVDR DCFARIAPGL PSNVIRIAES GVRGTNDLLA YAGAGADAVL 

       250        260        270 
VGEGLVKSGD PRAAVADLVT AGTHPSCPKP AR

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000854 Genomic DNA. Translation: ACC40863.1.
RefSeqYP_001850718.1. NC_010612.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB2HQX7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000034776; EBMYCP00000033216; EBMYCG00000034771.
GeneID6226678.
GenomeReviewsGene locus MMAR_2413 in contig CP000854_GR.
KEGGmmi:MMAR_2413.
PATRIC18065779. VBIMycMar75906_2571.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000017090.
HOGENOMHBG540956.
OMALEYAVPH.
ProtClustDBPRK00278.

Family and domain databases

HAMAPMF_00134_B. IGPS_B.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR013798. Indole-3-glycerol_P_synth.
IPR001468. Indole-3-GlycerolPSynthase_CS.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01609.
PfamPF00218. IGPS. 1 hit.
[Graphical view]
SUPFAMSSF51366. RibP_bind_barrel. 1 hit.
PROSITEPS00614. IGPS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTRPC_MYCMM
AccessionPrimary (citable) accession number: B2HQX7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: June 10, 2008
Last modified: January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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