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B2HQP4 (PSD_MYCMM) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:MMAR_0754
OrganismMycobacterium marinum (strain ATCC BAA-535 / M) [Complete proteome] [HAMAP]
Taxonomic identifier216594 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length240 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00664

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphatidylethanolamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncofactor binding

Inferred from electronic annotation. Source: InterPro

phosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 208208Phosphatidylserine decarboxylase beta chain By similarity
PRO_1000131472
Chain209 – 24032Phosphatidylserine decarboxylase alpha chain By similarity
PRO_1000131473

Sites

Site208 – 2092Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2091Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
B2HQP4 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: B277DD03CEA13681

FASTA24025,179
        10         20         30         40         50         60 
MARRPRRSDS SSAEPTLSPQ HLLALVRSTI PPIHPAGRPF IAAGLAVAGV GYRHRWARRT 

        70         80         90        100        110        120 
GLLAAGACAG FFRHPPRVPP SRAGAIVAPA DGVICVIDTA APPAELSMGD APLPRVSIFL 

       130        140        150        160        170        180 
SVFDAHVQRA PVSGEVVAVQ HRPGRFGSAD LPAASDDNER NSVRIRTANG AEVVAVQVAG 

       190        200        210        220        230        240 
LVARRIVCDA HVGDKLAIGD TYGLIRFGSR LDTYLPPGTE PVVRVGQRTI AGETILADLP

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000854 Genomic DNA. Translation: ACC39214.1.
RefSeqYP_001849069.1. NC_010612.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB2HQP4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000030972; EBMYCP00000029412; EBMYCG00000030967.
GeneID6225004.
GenomeReviewsGene locus MMAR_0754 in contig CP000854_GR.
KEGGmmi:MMAR_0754.
PATRIC18062227. VBIMycMar75906_0806.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000017584.
HOGENOMHBG541103.
OMAIFMSVFN.
ProtClustDBPRK05305.

Family and domain databases

HAMAPMF_00664. PS_decarb_type3.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR004428. PtdSer_deCO2ase-related.
[Graphical view]
KOK01613.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00164. PS_decarb_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_MYCMM
AccessionPrimary (citable) accession number: B2HQP4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 10, 2008
Last modified: January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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