B2HPE8 (B2HPE8_MYCMM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Methylmalonyl-CoA mutase large subunit, MutB EMBL ACC40752.1

Gene names

Name:	mutB EMBL ACC40752.1
Ordered Locus Names:	MMAR_2303 EMBL ACC40752.1

Organism

Mycobacterium marinum (strain ATCC BAA-535 / M) [Complete proteome] [HAMAP] EMBL ACC40752.1

Taxonomic identifier

216594 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium marinum

Protein attributes

Sequence length	753 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	cobalamin binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro methylmalonyl-CoA mutase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2HPE8 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: 67DBF3729D2278A2	FASTA	753	80,803
	10 20 30 40 50 60 MTTTASAIGS FADVPLHGER AVASATEAAV EKQVAATAAA HGYATDQLRW QTPEGIEVKP 70 80 90 100 110 120 VYIGADRRAA QADGYPVNSF PGEPPYVRGP YPTMYVNQPW TIRQYAGFST AADSNAFYRR 130 140 150 160 170 180 NLAAGQKGLS VAFDLATHRG YDSDHPRVQG DVGMAGVAID SILDMRQLFD GIDLSSVSVS 190 200 210 220 230 240 MTMNGAVLPI LALYVVAAEE QGVPPEKLAG TIQNDILKEF MVRNTYIYPP KPSMRIISDI 250 260 270 280 290 300 FAYTSAKMPK FNSISISGYH IQEAGATADL ELAYTLADGV DYIKAGLDAG LDIDKFAPRL 310 320 330 340 350 360 SFFWGIGMNF FMEVAKLRAG RLLWSELVAK FEPKNSKSRS LRTHSQTSGW SLTAQDVFNN 370 380 390 400 410 420 VARTCIEAMA ATQGHTQSLH TNALDEALAL PTDFSARIAR NTQLLLQQES GTTRPIDPWG 430 440 450 460 470 480 GSYYVEWLTH QLAQRARAHI NEVAELGGMA AAISEGIPKL RIEEAAARTQ ARIDSGQQPV 490 500 510 520 530 540 IGVNKYQVDE DQQIEVLKVE NSRVRAEQLA KLQELRAGRD QAAVDAALAE LTRAAAAHGR 550 560 570 580 590 600 AGDDGLGNNL LALAIDAARA KATVGEISDA LEQVYGRHQA EIRTIAGVYR DEVQGGGNIT 610 620 630 640 650 660 PLSKATELVE KFAEADGRRP RILVAKMGQD GHDRGQKVIA TAFADIGFDV DVGSLFSTPE 670 680 690 700 710 720 EVAREAADND VHVVGVSSLA AGHLTLVPAL RDALAKVGRP DIMIVVGGVI PPGDFDELYA 730 740 750 AGATAIYPPG TVIADAAIGL LHKLAERLGY PLD

References

[1]

"Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis." Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K., Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C., Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K., Lord A., Moule S. , Mungall K., Norbertczak H., Quail M.A., Rabbinowitsch E., Walker D., White B., Whitehead S., Small P.L., Brosch R., Ramakrishnan L., Fischbach M.A., Parkhill J., Cole S.T. Genome Res. 18:729-741(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-535 / M.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000854 Genomic DNA. Translation: ACC40752.1.
RefSeq	YP_001850607.1. NC_010612.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	216594.MMAR_2303.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACC40752; ACC40752; MMAR_2303.
GeneID	6226567.
KEGG	mmi:MMAR_2303.
PATRIC	18065553. VBIMycMar75906_2458.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2185.
HOGENOM	HOG000003917.
KO	K01847.
OMA	NDVHILG.
ProtClustDB	PRK09426.
Enzyme and pathway databases
BioCyc	MMAR216594:GJOB-2318-MONOMER.
Family and domain databases
Gene3D	3.20.20.240. 1 hit. 3.40.50.280. 1 hit.
InterPro	IPR006159. Acid_CoA_mut_C. IPR016176. Cbl-dep_enz_cat. IPR014348. Cbl-dep_enz_cat-sub. IPR006158. Cobalamin-bd. IPR006099. MeMalonylCoA_mutase_a/b_cat. IPR006098. MMCoA_mutase_a_cat. [Graphical view]
Pfam	PF02310. B12-binding. 1 hit. PF01642. MM_CoA_mutase. 1 hit. [Graphical view]
SUPFAM	SSF52242. Cbl-bd. 1 hit. SSF51703. Cbl-dep_enz_cat. 1 hit.
TIGRFAMs	TIGR00640. acid_CoA_mut_C. 1 hit. TIGR00641. acid_CoA_mut_N. 1 hit.
PROSITE	PS51332. B12_BINDING. 1 hit. PS00544. METMALONYL_COA_MUTASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2HPE8_MYCMM

Accession

Primary (citable) accession number: B2HPE8

Entry history

Integrated into UniProtKB/TrEMBL:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)