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B2HP45 (PYRF_MYCMM) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Orotidine 5'-phosphate decarboxylase

EC=4.1.1.23
Alternative name(s):
OMP decarboxylase
Short name=OMPDCase
Short name=OMPdecase
Gene names
Name:pyrF
Ordered Locus Names:MMAR_2200
OrganismMycobacterium marinum (strain ATCC BAA-535 / M) [Complete proteome] [HAMAP]
Taxonomic identifier216594 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium

Protein attributes

Sequence length278 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processPyrimidine biosynthesis
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_process'de novo' UMP biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

'de novo' pyrimidine nucleobase biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionorotidine-5'-phosphate decarboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 278278Orotidine 5'-phosphate decarboxylase HAMAP-Rule MF_01215
PRO_1000213894

Sites

Active site951Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
B2HP45 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: 65F60EDB8D5E794D

FASTA27827,837
        10         20         30         40         50         60 
MTGFGARLAE AKAHRGPLCL GIDPHPELLR AWDLPATADG LAAFCDICVA AFAGFAVVKP 

        70         80         90        100        110        120 
QVAFFEAYGA AGFAVLEGTM AALRANGVLV LADAKRGDIG STMAAYAAAW AGDSPLAADA 

       130        140        150        160        170        180 
VTVSPFLGFG SLRPLLEVAT ANDRGVFVLA ATSNPEGATI QRADADGRTV AQLIVDQVGL 

       190        200        210        220        230        240 
FNSEVGEVTG PEPGSVGVVV GATVLNPPDV SGLGGPVLVP GVGVQGGRPE ALGGLGGAAP 

       250        260        270 
QQLLPAVSRE VLRAGPSISE VRAAAERMLD SVAYLSAV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000854 Genomic DNA. Translation: ACC40649.1.
RefSeqYP_001850504.1. NC_010612.1.

3D structure databases

ProteinModelPortalB2HP45.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING216594.MMAR_2200.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACC40649; ACC40649; MMAR_2200.
GeneID6226464.
KEGGmmi:MMAR_2200.
PATRIC18065339. VBIMycMar75906_2351.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0284.
HOGENOMHOG000245748.
KOK01591.
OMAGSTMGAY.
OrthoDBEOG6DZF33.

Enzyme and pathway databases

BioCycMMAR216594:GJOB-2215-MONOMER.
UniPathwayUPA00070; UER00120.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_01215. OMPdecase_type2.
InterProIPR013785. Aldolase_TIM.
IPR018089. OMPdecase_AS.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
TIGRFAMsTIGR02127. pyrF_sub2. 1 hit.
PROSITEPS00156. OMPDECASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePYRF_MYCMM
AccessionPrimary (citable) accession number: B2HP45
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 10, 2008
Last modified: May 14, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways