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Protein
Submitted name:

Formamidopyrimidine-DNA glycosylase

Gene

MMAR_3812

Organism
Mycobacterium marinum (strain ATCC BAA-535 / M)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.SAAS annotation

Cofactori

Zn2+SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingSAAS annotation, GlycosidaseSAAS annotation, Hydrolase, LyaseSAAS annotation
Biological processDNA damage, DNA repairSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Formamidopyrimidine-DNA glycosylaseImported
Gene namesi
Ordered Locus Names:MMAR_3812Imported
OrganismiMycobacterium marinum (strain ATCC BAA-535 / M)Imported
Taxonomic identifieri216594 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000001190 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi216594.MMAR_3812.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini234 – 268FPG-typeInterPro annotationAdd BLAST35

Sequence similaritiesi

Belongs to the FPG family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CY4. Bacteria.
COG0266. LUCA.
HOGENOMiHOG000020880.
KOiK05522.
OMAiMGRPPRV.
OrthoDBiPOG091H01RH.

Family and domain databases

Gene3Di3.20.190.10. 1 hit.
InterProiView protein in InterPro
IPR015886. DNA_glyclase/AP_lyase_DNA-bd.
IPR015887. DNA_glyclase_Znf_dom_DNA_BS.
IPR012319. FPG_cat.
IPR035937. MutM-like_N-ter.
IPR010979. Ribosomal_S13-like_H2TH.
IPR000214. Znf_DNA_glyclase/AP_lyase.
IPR010663. Znf_FPG/IleRS.
PfamiView protein in Pfam
PF01149. Fapy_DNA_glyco. 1 hit.
PF06831. H2TH. 1 hit.
PF06827. zf-FPG_IleRS. 1 hit.
SMARTiView protein in SMART
SM00898. Fapy_DNA_glyco. 1 hit.
SM01232. H2TH. 1 hit.
SUPFAMiSSF46946. SSF46946. 1 hit.
SSF81624. SSF81624. 1 hit.
PROSITEiView protein in PROSITE
PS01242. ZF_FPG_1. 1 hit.
PS51066. ZF_FPG_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B2HNG9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPEGHTLHRL ARLHQRRFAG APVVVSSPQG KFADSAGAVD GRVLRAASAW
60 70 80 90 100
GKHLFHHYAG GPVVHVHLGL YGAFTEWARS AGELLPDPVG QVRMRMVGAE
110 120 130 140 150
YGTDLRGPTV CEVIDDAQVA DVLARLGPDP LRKDADPSWA WARIAKSRRP
160 170 180 190 200
IGALLMDQKV MAGVGNVYRS ELLFRHRIDP YRSGQRITEA EFSAAWTDLV
210 220 230 240 250
ALMKVGLRGG KIVVVRPEHD HGAPSYAAGR PRTYVYRRAG DPCRVCGATV
260
GTAVLEGRNV FWCPSCQA
Length:268
Mass (Da):29,203
Last modified:June 10, 2008 - v1
Checksum:i8F0DB320AE2A3764
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000854 Genomic DNA. Translation: ACC42222.1.
RefSeqiWP_012395412.1. NC_010612.1.

Genome annotation databases

EnsemblBacteriaiACC42222; ACC42222; MMAR_3812.
KEGGimmi:MMAR_3812.

Similar proteinsi

Entry informationi

Entry nameiB2HNG9_MYCMM
AccessioniPrimary (citable) accession number: B2HNG9
Entry historyiIntegrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: October 25, 2017
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Multifunctional enzymeSAAS annotation, Reference proteomeImported