B2HKL5 (B2HKL5_MYCMM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Bifunctional Mta/Sah nucleosidase Mtn EMBL ACC38720.1

Gene names

Name:	mtn EMBL ACC38720.1
Ordered Locus Names:	MMAR_0251

Organism

Mycobacterium marinum (strain ATCC BAA-535 / M) [Complete proteome] [HAMAP]

Taxonomic identifier

216594 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	251 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

S-adenosyl-L-homocysteine + H2O = S-(5-deoxy-D-ribos-5-yl)-L-homocysteine + adenine. SAAS SAAS010049 S-methyl-5'-thioadenosine + H2O = S-methyl-5-thio-D-ribose + adenine. SAAS SAAS010049

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Methionine biosynthesis SAAS SAAS010049
Molecular function	Hydrolase SAAS SAAS010049
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	L-methionine salvage from methylthioadenosine Inferred from electronic annotation. Source: InterPro nucleoside catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	adenosylhomocysteine nucleosidase activity Inferred from electronic annotation. Source: InterPro methylthioadenosine nucleosidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2HKL5 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: A1582E857C6C3335	FASTA	251	26,874
	10 20 30 40 50 60 MTIGVICAIP QELAYLRTNL VAADQQEIAQ ICFYAGQLGD RRVVLTAAGM GKVNAGLVAT 70 80 90 100 110 120 LLADRFDCHT VIFTGVAGGL DPALSIGDIV IADRVVQHDC GLLTDDGLQP YQPGHVPFIK 130 140 150 160 170 180 PTEQLGYRVD PELLDRVKHR LEDFTLPALS AAAGGGARPP RINYGTILTG DQYLHSARTR 190 200 210 220 230 240 DQLYNDFAGM AIEMEGGALA QVCESFAIPW LVIRALSDLA GAGSGLDFNR FVDEVSVSSA 250 RILLHLLSVV D

References

[1]

"Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis." Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K., Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C., Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K., Lord A., Moule S. , Mungall K., Norbertczak H., Quail M.A., Rabbinowitsch E., Walker D., White B., Whitehead S., Small P.L., Brosch R., Ramakrishnan L., Fischbach M.A., Parkhill J., Cole S.T. Genome Res. 18:729-741(2008) [PubMed: 18403782] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000854 Genomic DNA. Translation: ACC38720.1.
RefSeq	YP_001848575.1. NC_010612.1.
3D structure databases
ProteinModelPortal	B2HKL5.
ModBase	Search...
Protein-protein interaction databases
STRING	B2HKL5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000033126; EBMYCP00000031566; EBMYCG00000033121.
GeneID	6224467.
GenomeReviews	Gene locus MMAR_0251 in contig CP000854_GR.
KEGG	mmi:MMAR_0251.
PATRIC	18061189. VBIMycMar75906_0288.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000018357.
HOGENOM	HBG367723.
OMA	NVFWINT.
ProtClustDB	CLSK790256.
Family and domain databases
InterPro	IPR010049. MTA_SAH_Nsdase. IPR018017. Nucleoside_phosphorylase. IPR000845. Nucleoside_phosphorylase_d. [Graphical view]
KO	K01243.
PANTHER	PTHR21234. PNP_UDP. 1 hit. PTHR21234:SF6. PTHR21234:SF6. 1 hit.
Pfam	PF01048. PNP_UDP_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR01704. MTA/SAH-Nsdase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B2HKL5_MYCMM

Accession

Primary (citable) accession number: B2HKL5

Entry history

Integrated into UniProtKB/TrEMBL:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)