B2HK97 (B2HK97_MYCMM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Selenide, water dikinase HAMAP MF_00625
EC=2.7.9.3 HAMAP MF_00625

Alternative name(s):
Selenium donor protein HAMAP MF_00625
Selenophosphate synthase HAMAP MF_00625

Gene names

Name:	selD HAMAP MF_00625
Ordered Locus Names:	MMAR_5189

Organism

Mycobacterium marinum (strain ATCC BAA-535 / M) [Complete proteome] [HAMAP]

Taxonomic identifier

216594 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	338 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Synthesizes selenophosphate from selenide and ATP By similarity. HAMAP MF_00625 SAAS SAAS023061
Catalytic activity	ATP + selenide + H2O = AMP + selenophosphate + phosphate. HAMAP MF_00625 SAAS SAAS023061
Cofactor	Magnesium By similarity. HAMAP MF_00625 SAAS SAAS023061
Sequence similarities	Belongs to the selenophosphate synthase 1 family. Class I subfamily. HAMAP MF_00625

Ontologies

Keywords
Ligand	ATP-binding HAMAP MF_00625 SAAS SAAS023061 Magnesium HAMAP MF_00625 SAAS SAAS023061 Nucleotide-binding Selenium HAMAP MF_00625 SAAS SAAS023061
Molecular function	Kinase HAMAP MF_00625 SAAS SAAS023061 EMBL ACC43594.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP selenide, water dikinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	234 – 240	7	ATP By similarity HAMAP MF_00625
Sites
	Active site	21	1	By similarity HAMAP MF_00625
	Site	24	1	Important for catalytic activity By similarity HAMAP MF_00625

Sequences

	Sequence		Length	Mass (Da)
	B2HK97 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: D3799FA7D488E05A	FASTA	338	34,565
	10 20 30 40 50 60 MGMVTDQGTY RLTQYAHGGG CACKIPPGEL EDVVRGLGAA APRDPVGELL VGLESGDDAA 70 80 90 100 110 120 AVLIAEGTAL IATTDFFTPV VDDPYDWGRI AATNALSDVY AMGGRPVVAV NLLGWPRDVL 130 140 150 160 170 180 PFELATETLR GGRDVCASAG CHLAGGHSVD DPEPKYGLAV TGIADPNRLL RNDSGRPGTP 190 200 210 220 230 240 LSLTKPLGIG VLNSRHKATG ERFAQAIDAM TTLNADAAAA AVAAGVECAT DITGFGLLGH 250 260 270 280 290 300 LHKLARASGV TAVIDSTAVP YLDGARQALA AGYVSGGTRR NLEWVGPHVD LSAVDESEAL 310 320 330 LLADAQTSGG LLIAGEIPGA PVIGELVARR AGHTIVVR

References

[1]

"Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis." Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K., Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C., Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K., Lord A., Moule S. , Mungall K., Norbertczak H., Quail M.A., Rabbinowitsch E., Walker D., White B., Whitehead S., Small P.L., Brosch R., Ramakrishnan L., Fischbach M.A., Parkhill J., Cole S.T. Genome Res. 18:729-741(2008) [PubMed: 18403782] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000854 Genomic DNA. Translation: ACC43594.1.
RefSeq	YP_001853449.1. NC_010612.1.
3D structure databases
ProteinModelPortal	B2HK97.
ModBase	Search...
Protein-protein interaction databases
STRING	B2HK97.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000031548; EBMYCP00000029988; EBMYCG00000031543.
GeneID	6229483.
GenomeReviews	Gene locus MMAR_5189 in contig CP000854_GR.
KEGG	mmi:MMAR_5189.
PATRIC	18071801. VBIMycMar75906_5555.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000016380.
HOGENOM	HBG383791.
OMA	DYIAQGC.
ProtClustDB	CLSK924712.
Family and domain databases
HAMAP	MF_00625. SelD. [Tree]
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR016188. PurM_N-like. IPR004536. SelD. IPR023061. SelD_I. [Graphical view]
KO	K01008.
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
PIRSF	PIRSF036407. Selenphspht_syn. 1 hit.
SUPFAM	SSF56042. AIR_synth_C. 1 hit. SSF55326. PurM_N-like. 1 hit.
TIGRFAMs	TIGR00476. SelD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B2HK97_MYCMM

Accession

Primary (citable) accession number: B2HK97

Entry history

Integrated into UniProtKB/TrEMBL:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)